Calcium Signalling: Mitofusins Promote Interorganellar Crosstalk

Current Biology

Volumn 19, Issue 5, 2009, Pages

  Parekh, Anant ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DYNAMIN; MEMBRANE PROTEIN; MFN2 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN;

ANIMAL; CALCIUM SIGNALING; ENDOPLASMIC RETICULUM; GENETICS; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SHORT SURVEY;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CHARCOT-MARIE-TOOTH DISEASE; DYNAMINS; ENDOPLASMIC RETICULUM; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS;

EID: 61449152887     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2009.01.012     Document Type: Short Survey

References (20)

1. Berridge M.J., Bootman M.D., and Roderick H.L. Calcium signalling: dynamics, homeostasis and remodelling. Nat. Rev. Mol. Cell Biol. 4 (2003) 517-529
2. Rizzuto R., Pinton P., Ferrari D., Chami M., Szabadkai G., Magalhaes P.J., Di Virgilio F., and Pozzan T. Calcium and apoptosis: facts and hypotheses. Oncogene 22 (2003) 8619-8627
3. de Brito O.M., and Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456 (2008) 605-610
4. Rizzuto R., and Pozzan T. Microdomains of intracellular calcium: molecular determinants and functional consequences. Physiol. Rev. 86 (2006) 369-408
5. McCormack J.G., Halestrap A.P., and Denton R.M. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70 (1990) 391-425
6. Landolfi B., Curci S., Debellis L., Pozzan T., and Hofer A.M. Ca2+ homeostasis in the agonist-sensitive internal store: functional interactions between mitochondria and the ER measured in situ in intact cells. J. Cell Biol. 142 (1998) 1235-1243
7. Gunter T.E., and Pfeiffer D.R. Mechanisms by which mitochondria transport calcium. Am. J. Physiol. 258 (1990) C755-C786
8. Rizzuto R., Brini M., Murgia M., and Pozzan T. Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria. Science 262 (1993) 744-747
9. Moreau B., Nelson C., and Parekh A.B. Biphasic regulation of mitochondrial Ca uptake by cytosolic Ca concentration. Curr. Biol. 16 (2006) 1672-1677
10. Csordas G., Renken C., Varnai P., Walter L., Weaver D., Buttle K.F., Balla T.M., Mannella C.A., and Hajnoczky G. Structural and functional features and significance of the physical linkage between ER and mitochondria. J. Cell Biol. 174 (2006) 915-921
11. Vance J.E. Phospholipid synthesis in a membrane fraction associated with mitochondria. J. Biol. Chem. 265 (1990) 7248-7256
12. Hayashi T., and Su T.P. Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca2+ signalling and cell survival. Cell 131 (2007) 596-610
13. Simmen T., Aslan J.E., Blagoveschenskaya A.D., Thomas L., Wan L., Xiang Y., Feliciangeli S.F., Hung C.H., Crump C.M., and Thomas G. PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis. EMBO J. 24 (2005) 717-729
14. Szabadkai G., Bianchi K., Varnai P., De Stefani D., Wieckowski M.R., Cavagna D., Nagy A.I., Balla T., and Rizzuto R. Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. J. Cell Biol. 175 (2006) 901-911
15. Bereiter-Hahn J., and Voth M. Dynamics of mitochondria in living cells: shape changes, dislocation, fusion, and fission of mitochondria. Micros. Res. Tech. 27 (1994) 198-219
16. Chen H., Detmer S.A., Ewald A.J., Griffin E.E., Fraser S.E., and Chan D.C. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol. 160 (2003) 189-200
17. Lewis R.S. The molecular choreography of a store-operated calcium channel. Nature 446 (2007) 284-287
18. Parekh A.B. Ca2+ microdomains near plasma membrane Ca2+ channels: impact on cell function. J. Physiol. 586 (2008) 3043-3054
19. Chang W.C., Di Capite J., Singaravelu K., Nelson C., Halse V., and Parekh A.B. Local calcium influx through calcium release-activated calcium (CRAC) channels stimulates production of an intracellular messenger and an intercellular pro-inflammatory signal. J. Biol. Chem. 283 (2008) 4622-4631
20. Mogami H., Nakano K., Tepikin A.V., and Petersen O.H. Ca2+ flow via tunnels in polarized cells: recharging of apical Ca2+ stores by focal Ca2+ entry through basal membrane patch. Cell 88 (1997) 49-55