Characterization of macroprolactin and assessment of markers of autoimmunity in macroprolactinaemic patients

Clinical Endocrinology

Volumn 70, Issue 4, 2009, Pages 599-605

  Kavanagh Wright, Lucille ^a   Smith, Thomas P ^a   Gibney, James ^b   McKenna, T Joseph ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b ADELAIDE AND MEATH HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; ANTINUCLEAR ANTIBODY; C REACTIVE PROTEIN; CD5 ANTIGEN; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; MACROGOL; MACROPROLACTIN; PROLACTIN DERIVATIVE; PROTEIN A; PROTEIN A SEPHAROSE; PROTEIN G; PROTEIN G SEPHAROSE; THIOCYANATE SODIUM; THYROID ANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; AUTOIMMUNITY; B LYMPHOCYTE; COHORT ANALYSIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISSOCIATION; ENDOCRINE DISEASE; FEMALE; GEL FILTRATION CHROMATOGRAPHY; HUMAN; HYPERPROLACTINEMIA; MACROPROLACTINEMIA; MAJOR CLINICAL STUDY; MALE; MOLECULAR WEIGHT; PRIORITY JOURNAL; SERUM; ULTRAFILTRATION;

AUTOIMMUNITY; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHROMATOGRAPHY, AGAROSE; CHROMATOGRAPHY, GEL; FEMALE; HUMANS; HYPERPROLACTINEMIA; IMMUNOGLOBULIN G; IMMUNOPRECIPITATION; MALE; PROLACTIN; ULTRAFILTRATION;

EID: 61449139247     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2008.03402.x     Document Type: Article

References (38)

1. Suh, H.K. Frantz, A.G. (1974) Size heterogeneity of human prolactin in plasma and pituitary extracts. Journal of Clinical Endocrinology and Metabolism, 39, 928 935.
2. Jackson, R.D., Wortsman, J. Malarkey, W.B. (1985) Characterization of a large molecular weight prolactin in women with idiopathic hyperprolactinemia and normal menses. Journal of Clinical Endocrinology and Metabolism, 61, 258 264.
3. Suliman, A.M., Smith, T.P., Gibney, J. et al. (2003) Frequent misdiagnosis and mismanagement of hyperprolactinemic patients before the introduction of macroprolactin screening: application of a new strict laboratory definition of macroprolactinemia. Clinical Chemistry, 49, 1504 1509.
4. Gibney, J., Smith, T.P. McKenna, T.J. (2005) The impact on clinical practice of routine screening for macroprolactin. Journal of Clinical Endocrinology and Metabolism, 90, 3927 3932.
5. Smith, T.P., Suliman, A.M., Fahie-Wilson, M.N. et al. (2002) Gross variability in the detection of prolactin in sera containing big big prolactin (macroprolactin) by commercial immunoassays. Journal of Clinical Endocrinology and Metabolism, 87, 5410 5415.
6. Olukoga, A.O., Dornan, T.L. Kane, J.W. (1999) Three cases of macroprolactinaemia. Journal of the Royal Society of Medicine, 92, 342 344.
7. Whittaker, P.G., Wilcox, T. Lind, T. (1981) Maintained fertility in a patient with hyperprolactinemia due to big, big prolactin. Journal of Clinical Endocrinology and Metabolism, 53, 863 866.
8. Pansini, F., Bergamini, C.M., Malfaccini, M. et al. (1985) Multiple molecular forms of prolactin during pregnancy in women. Journal of Endocrinology, 106, 81 85.
9. Tanaka, T., Yano, H., Umezawa, S. et al. (1989) Heterogeneity of big-big hPRL in hyperprolactinemia. Hormone and Metabolic Research, 21, 84 88.
10. Carlson, H.E., Markoff, E. Lee, D.W. (1992) On the nature of serum prolactin in two patients with macroprolactinemia. Fertility and Sterility, 58, 78 87.
11. Hattori, N. (1996) The frequency of macroprolactinemia in pregnant women and the heterogeneity of its etiologies. Journal of Clinical Endocrinology and Metabolism, 81, 586 590.
12. Mounier, C., Trouillas, J., Claustrat, B. et al. (2003) Macroprolactinaemia associated with prolactin adenoma. Human Reproduction, 18, 853 857.
13. Leite, V., Cosby, H., Sobrinho, L.G. et al. (1992) Characterization of big, big prolactin in patients with hyperprolactinaemia. Clinical Endocrinology, 37, 365 372.
14. Hattori, N., Ikekubo, K., Ishihara, T. et al. (1992) A normal ovulatory woman with hyperprolactinemia: presence of anti- prolactin autoantibody and the regulation of prolactin secretion. Acta Endocrinologica (Copenhagen), 126, 497 500.
15. Hattori, N., Ishihara, T., Ikekubo, K. et al. (1992) Autoantibody to human prolactin in patients with idiopathic hyperprolactinemia. Journal of Clinical Endocrinology and Metabolism, 75, 1226 1229.
16. Kavanagh, L., McKenna, T.J., Fahie-Wilson, M.N. et al. (2006) Specificity and clinical utility of methods for the detection of macroprolactin. Clinical Chemistry, 52, 1366 1372.
17. + B cells is associated with mild disease in chronic hepatitis C virus infection. Journal of Hepatology, 32, 121 125.
18. Barchet, W., Price, J.D., Cella, M. et al. (2006) Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation. Blood, 107, 1497 504.
19. Furumoto, Y., Brooks, S., Olivera, A. et al. (2006) Cutting Edge: Lentiviral short hairpin RNA silencing of PTEN in human mast cells reveals constitutive signals that promote cytokine secretion and cell survival. Journal of Immunology, 176, 5167 5171.
20. Bjoro, T., Morkrid, L., Wergeland, R. et al. (1995) Frequency of hyperprolactinaemia due to large molecular weight prolactin (150-170 kD PRL). Scandinavian Journal of Clinical Laboratory Investigations, 55, 139 147.
21. Hattori, N. Inagaki, C. (1997) Anti-prolactin (PRL) autoantibodies cause asymptomatic hyperprolactinemia: bioassay and clearance studies of PRL-immunoglobulin G complex. Journal of Clinical Endocrinology and Metabolism, 82, 3107 3110.
22. Walker, A.M., Montgomery, D.W., Saraiya, S. et al. (1995) Prolactin-immunoglobulin G complexes from human serum act as costimulatory ligands causing proliferation of malignant B lymphocytes. Proceedings of the National Academy of Sciences of the USA, 92, 3278 3282.
23. Lindmark, R., Thoren-Tolling, K. Sjoquist, J. (1983) Binding of immunoglobulins to protein A and immunoglobulin levels in mammalian sera. Journal of Immunological Methods, 62, 1 13.
24. Akerstrom, B., Brodin, T., Reis, K. et al. (1985) Protein G: a powerful tool for binding and detection of monoclonal and polyclonal antibodies. Journal of Immunology, 135, 2589 2592.
25. Vondra, K., Vrbikova, J. Dvorakova, K. (2005) Thyroid gland diseases in adult patients with diabetes mellitus. Minerva Endocrinologica, 30, 217 236.
26. Biro, E., Szekanecz, Z., Czirjak, L. et al. (2006) Association of systemic and thyroid autoimmune diseases. Clinical Rheumatology, 25, 240 245.
27. Leanos-Miranda, A. Cardenas-Mondragon, G. (2006) Serum free prolactin concentrations in patients with systemic lupus erythematosus are associated with lupus activity. Rheumatology, 45, 97 101.
28. Vanderpump, M.P., French, J.M., Appleton, D. et al. (1998) The prevalence of hyperprolactinaemia and association with markers of autoimmune thyroid disease in survivors of the Whickham Survey cohort. Clinical Endocrinology, 48, 39 44.
29. Kramer, C.K., Tourinho, T.F., de Castro, W.P. et al. (2005) Association between systemic lupus erythematosus, rheumatoid arthritis, hyperprolactinemia and thyroid autoantibodies. Archives of Medical Research, 36, 54 58.
30. Neidhart, M. (1996) Elevated serum prolactin or elevated prolactin/cortisol ratio are associated with autoimmune processes in systemic lupus erythematosus and other connective tissue diseases. Journal of Rheumatology, 23, 476 481.
31. Rezaieyazdi, Z. Hesamifard, A. (2006) Correlation between serum prolactin levels and lupus activity. Rheumatology International, 26, 1036 1039.
32. Reuman, P.D. (2004) First reported pediatric case of systemic lupus erythematosus associated with prolactinoma. Arthritis and Rheumatism, 50, 3616 3618.
33. Vera-Lastra, O., Mendez, C., Jara, L.J. et al. (2003) Correlation of prolactin serum concentrations with clinical activity and remission in patients with systemic lupus erythematosus. Effect of conventional treatment. Journal of Rheumatology, 30, 2140 2146.
34. Dauphinee, M., Tovar, Z. Talal, N. (1988) B cells expressing CD5 are increased in Sjogren's syndrome. Arthritis and Rheumatism, 31, 642 647.
35. + B lymphocytes, polyreactive antibodies and the human B-cell repertoire. Immunology Today, 10, 364 368.
36. + B lymphocytes and the activity of systemic autoimmunity. Clinical Immunology and Immunopathology, 56, 219 225.
37. + B cells and T cell receptor (TCR) Δ+ T cells are associated with younger age of onset in rheumatoid arthritis (RA). Clinical Experimental Immunology, 103, 353 356.
38. Hattori, N., Nakayama, Y., Kitagawa, K. et al. (2007) Development of anti-PRL (prolactin) autoantibodies by homologous PRL in rats: a model for macroprolactinemia. Endocrinology, 148, 2465 2470.