Methyl isobutyl ketone (MIBK) induction of α2u-globulin nephropathy in male, but not female rats

Toxicology

Volumn 258, Issue 2-3, 2009, Pages 131-138

  Borghoff, S J ^a   Hard, G C ^b   Berdasco, N M ^c   Gingell, R ^d   Green, S M ^e   Gulledge, W ^a  

^a INTEGRATED LABORATORY SYSTEMS   (United States)

^b Dow Chemical Company ^*

^c SHELL OIL COMPANY   (United States)

^d EASTMAN CHEMICAL COMPANY   (United States)

^e AMERICAN CHEMISTRY COUNCIL   (United States)

Author keywords

2u Globulin; Methyl isobutyl ketone; Protein droplet nephropathy

Indexed keywords

4 METHYL 2 PENTANONE; ALPHA GLOBULIN; ALPHA2U GLOBULIN; CORN OIL; CYCLINE; HYALIN; LIMONENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; KIDNEY CELL; KIDNEY MASS; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE;

ADMINISTRATION, ORAL; ALPHA-GLOBULINS; ANIMALS; CELL PROLIFERATION; FEMALE; IMMUNOHISTOCHEMISTRY; KIDNEY DISEASES; MALE; METHYL N-BUTYL KETONE; ORGAN SIZE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, INBRED F344;

RATTUS; ZEA MAYS;

EID: 61449109914     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.01.018     Document Type: Article

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