Biotransformation of methyl cholate by Aspergillus niger

Steroids

Volumn 74, Issue 4-5, 2009, Pages 483-486

  Al Aboudi, Amal ^a   Mohammad, Mohammad Y ^b   Haddad, Salim ^a   Al Far, Rawhi ^a,c   Choudhary, M Iqbal ^b   Atta ur Rahman, ^b  

^a UNIVERSITY OF JORDAN   (Jordan)

^b UNIVERSITY OF KARACHI   (Pakistan)

^c AL BALQA APPLIED UNIVERSITY   (Jordan)

Author keywords

Aspergillus niger; Biotransformation; Methyl 3 ,12 dihydroxy 7 oxo 5 cholan 24 oate; Methyl 3 ,7 ,12 ,15 tetrahydroxy 5 cholan 24 oate; Methylcholate

Indexed keywords

CHOLIC ACID; CHOLIC ACID DERIVATIVE;

ARTICLE; ASPERGILLUS NIGER; BIOTRANSFORMATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; ISOLATION PROCEDURE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

ASPERGILLUS NIGER; BIOTRANSFORMATION; CHOLATES; CRYSTALLOGRAPHY, X-RAY; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR;

ASPERGILLUS NIGER;

EID: 61349203805     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2009.01.002     Document Type: Article

References (17)

1. Virtanen E., and Kolehmainen E. Use of bile acids in pharmacological and supramolecular applications. Eur J Org Chem 16 (2004) 3385-3399
2. Colombo C., Setchell K.D.R., Podda M., Curcio L., Ronchi M., and Giunta A. The effects of ursodeoxycholic acid therapy in liver disease associated with cystic fibrosis. J Pediatr 117 (1990) 482-489
3. Crosignani A., Setchell K.D.R., Invernizzi P., Larghi A., Rodrigues C.M.P., and Podda M. Clinical pharmacokinetics of therapeutic bile acids. Clin Pharmacokinet 30 (1996) 333-358
4. Bortolini O., Medici A., and Poli S. Biotransformations on steroid nucleus of bile acids. Steroids 62 (1997) 564-577
5. Fantin G., Ferrarini S., Medici A., Pedrini P., and Poli S. Regioselective microbial oxidation of bile acids. Tetrahedron 54 (1998) 1937-1942
6. Canzi E., Maconi E., Aragozzini F., and Ferrari A. Cooperative 3-epimerization of chenodeoxycholic acid by Clostridium innocuum and Eubacterium lentum. Curr Microbiol 18 (1989) 335-338
7. Hirano S., and Masuda N. Epimerization of the 7-hydroxy group of bile acids by the combination of two kinds of microorganisms with 7α- and 7β-hydroxysteroid dehydrogenase activity, respectively. J Lipid Res 22 (1981) 1060-1068
8. Carlstrom K., Kirk D., and Sjovall J. Microbial synthesis of 1β- and 15β-hydroxylated bile acids. J Lipid Res 22 (1981) 1225-1234
9. Hayakawa S. Microbial transformation of bile acids, a unified scheme for bile acid degradation and hydroxylation of bile acids. Zeitschrift Allgemeine Mikrobiologie 22 (1982) 309-326
10. Sawada H., Kulprecha S., and Nilubol N. Microbial production of ursodeoxycholic acid from lithocholic acid by Fusarium equiseti M41. Appl Environ Mirob 44 (1982) 1249-1252
11. Rigaku. Crystal clear. Rigaku Corporation, Tokyo, Japan; 2000.
12. Bruker, SHELXTL (including XPREP, XCIF, XL, XP, XS) Version 6.10. Bruker AXS Inc., Madison, WI, USA; 2001.
13. Iida T., Hikosaka M., Kakiyama G., Shiraishi K., Schteingart C., Hagey L., et al. Potential bile acid metabolites. 25. Synthesis and chemical properties of stereoisomeric 3α,7α,16- and 3α,7α,15-trihydroxy-5β-cholan-24-oic acids. Chem Pharm Bull 50 (2002) 1327-1334
14. 13C NMR study. Il Farmaco 55 (2000) 51-55
15. Kulprecha S., Nihira T., Shimomura C., Yamada K., Nilubol N., Yoshida T., et al. 15β-Hydroxylation of lithocholic acid by Cunninghamella sp. Tetrahedron 40 (1984) 2843-2846
16. Riva S., Bovara R., Pasta P., and Carrea G. Preparative-scale regio- and stereospecific oxidoreduction of cholic acid and dehydrocholic acid catalyzed by hydroxysteroid dehydrogenases. J Org Chem 51 (1986) 2902-2906
17. Bovarar R., Carrea G., Riva S., and Secundo F. A new enzymatic route to the sun thesis of 12-ketoursodeoxycholic acid. Biotechnol Lett 18 (1996) 305-308