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16
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0008610732
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2O
-
The stereoview of structure II has been adapted from the crystal structure of cholic acid: AM1 calculations have shown that the structure is slightly distorted in the presence of oxo groups. Functions at C-3, C-7, C-12 and side chain have been omitted for clarity
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Note that the nomenclature axial-equatorial refers to ring B and the configurational assignment of the proton at C-6 as axial is proposed by analogy with other protons under discussion. The experimental results and the dihedral angle of ca. 90°, however, are consistent with both axial and equatorial configuration for the proton at C-6
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Note that the nomenclature axial-equatorial refers to ring B and the configurational assignment of the proton at C-6 as axial is proposed by analogy with other protons under discussion. The experimental results and the dihedral angle of ca. 90°, however, are consistent with both axial and equatorial configuration for the proton at C-6.
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18
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0342817500
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