Multiplex expression cloning of blood-brain barrier membrane proteins

Proteomics

Volumn 9, Issue 4, 2009, Pages 1099-1108

  Agarwal, Nitin ^a   Shusta, Eric V ^a  

^a Wisconsin Electric Machines and Power Electronics Consortium   (United States)

Author keywords

Blood brain barrier; Brain endothelial cells; Brain microvasculature; Expression cloning; Membrane proteomics

Indexed keywords

MEMBRANE PROTEIN; POLYCLONAL ANTISERUM; PROTEOME;

ANIMAL CELL; ANTIBODY LABELING; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DNA ISOLATION; DNA LIBRARY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HOST CELL; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD-BRAIN BARRIER; CELL LINE; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COS CELLS; ELECTROPHORESIS, AGAR GEL; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE LIBRARY; HUMANS; IMMUNE SERA; MEMBRANE PROTEINS; REPRODUCIBILITY OF RESULTS;

MAMMALIA;

EID: 61349157892     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200800368     Document Type: Article

References (44)

1. Shusta, E. V., Blood-brain barrier genomics, proteomics, and new transporter discovery. Neuro Rx 2005, 2, 151-161.
2. Madden, S. L., Cook, B. P., Nacht, M., Weber, W. D. et al., Vascular gene expression in nonneoplastic and malignant brain. Am. J. Pathol. 2004, 165, 601-608.
3. Calabria, A. R., Shusta, E. V., Blood-brain barrier genomics and proteomics: Elucidating phenotype, identifying disease targets and enabling brain drug delivery. Drug Discov. Today 2006, 11, 792-799.
4. Enerson, B. E., Drewes, L. R., The rat blood-brain barrier transcriptome. J. Cereb. Blood Flow Metab. 2006, 26, 959-973.
5. Pardridge, W. M., Blood-brain barrier genomics. Stroke 2007, 38, 686-690.
6. Elias, J. E., Haas, W., Faherty, B. K., Gygi, S. P., Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations. Nat. Methods 2005, 2, 667-675.
7. Schindler, J., Lewandrowski, U., Sickmann, A., Friauf, E., Nothwang, H. G., Proteomic analysis of brain plasma membranes isolated by affinity two-phase partitioning. Mol. Cell. Proteomics 2006, 5, 390-400.
8. Wang, H., Qian, W. J., Chin, M. H., Petyuk, V. A. et al., Char-acterization of the mouse brain proteome using global proteomic analysis complemented with cysteinyl-peptide enrichment. J. Proteome Res. 2006, 5, 361-369.
9. Wu, L., Han, D. K., Overcoming the dynamic range problem in mass spectrometry-based shotgun proteomics. Expert Rev. Proteomics 2006, 3, 611-619.
10. Cech, N. B., Enke, C. G., Relating electrospray ionization response to nonpolar character of small peptides. Anal. Chem. 2000, 72, 2717-2723.
11. Grant, K. J., Wu, C. C., Advances in neuromembrane prote-omics: Efforts towards a comprehensive analysis of membrane proteins in the brain. Brief Funct. Genomic Proteomic 2007, 6, 59-69.
12. Shusta, E. V., Boado, R. J., Pardridge, W. M., Vascular proteomics and subtractive antibody expression cloning. Mol. Cell. Proteomics 2002, 1, 75-82.
13. Shusta, E. V., Zhu, C., Boado, R. J., Pardridge, W. M., Sub-tractive expression cloning reveals high expression of CD46 at the blood-brain barrier. J. Neuropathol. Exp. Neurol. 2002, 61, 97-604.
14. Shusta, E. V., Li, J. Y., Boado, R. J., Pardridge, W. M., The Ro52/SS-A autoantigen has elevated expression at the brain microvasculature. Neuroreport 2003, 14, 1861-1865.
15. Pardridge, W. M., Yang, J., Buciak, J. L., Boado, R. J., Differential expression of 53- and 45-kDa brain capillary-specific proteins by brain capillary endothelium and choroid plexus in vivo and by brain capillary endothelium in tissue culture. Mol. Cell. Neurosci. 1990, 1, 20-28.
16. Jordan, M., Wurm, F., Transfection of adherent and suspended cells by calcium phosphate. Methods 2004, 33, 136-143.
17. Mellon, P., Parker, V., Gluzman, Y., Maniatis, T., Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system. Cell 1981, 27, 279-288.
18. Chakrabarti, S., Joffe, S., Seidman, M. M., Recombination and deletion of sequences in shuttle vector plasmids in mammalian cells. Mol. Cell. Biol. 1985, 5, 2265-2271.
19. Graham, F. L., Smiley, J., Russell, W. C., Nairn, R., Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 1977, 36, 59-74.
20. Miller, J. H., Lebkowski, J. S., Greisen, K. S., Calos, M. P., Specificity of mutations induced in transfected DNA by mammalian cells. EMBO J. 1984, 3, 3117-3121.
21. Lebkowski, J. S., DuBridge, R. B., Antell, E. A., Greisen, K. S., Calos, M. P., Transfected DNA is mutated in monkey, mouse, and human cells. Mol. Cell. Biol. 1984, 4, 1951-1960.
22. Ghandour, M. S., Langley, O. K., Zhu, X. L., Waheed, A., Sly, W. S., Carbonic anhydrase IV on brain capillary endothelial cells: A marker associated with the blood-brain barrier. Proc. Natl. Acad. Sci. USA 1992, 89, 6823-6827.
23. Calabria, A. R., Shusta, E. V., A genomic comparison of in vivo and in vitro brain microvascular endothelial cells. J. Cereb. Blood Flow Metab. 2008, 28, 135-148.
24. Udani, M., Zen, Q., Cottman, M., Leonard, N. et al., Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin. J. Clin. Invest. 1998, 101, 2550-2558.
25. Boado, R. J., Li, J. Y., Pardridge, W. M., Selective Lutheran glycoprotein gene expression at the blood-brain barrier in normal brain and in human brain tumors. J. Cereb. Blood Flow Metab. 2000, 20, 1096-1102.
26. Seya, T., Hirano, A., Matsumoto, M., Nomura, M., Ueda, S., Human membrane cofactor protein (MCP, CD46): Multiple isoforms and functions. Int. J. Biochem. Cell Biol. 1999, 31, 1255-1260.
27. Wulfkuhle, J. D., Donina, I. E., Stark, N. H., Pope, R. K. et al., Domain analysis of supervillin, an F-actin bundling plasma membrane protein with functional nuclear localization signals. J. Cell. Sci. 1999, 112, 2125-2136.
28. Vidal, R., Delisle, M. B., Ghetti, B., Neurodegeneration caused by proteins with an aberrant carboxyl-terminus. J. Neuropathol. Exp. Neurol. 2004, 63, 787-800.
29. Bradshaw, A. D., Sage, E. H., SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury. J. Clin. Invest. 2001, 107, 1049-1054.
30. Goldblum, S. E., Ding, X., Funk, S. E., Sage, E. H., SPARC (secreted protein acidic and rich in cysteine) regulates endothelial cell shape and barrier function. Proc. Natl. Acad. Sci. USA 1994, 91, 3448-3452.
31. Pen, A., Moreno, M. J., Martin, J., Stanimirovic, D. B., Molecular markers of extracellular matrix remodeling in glio-blastoma vessels: Microarray study of laser-captured glioblastoma vessels. Glia 2007, 55, 559-572.
32. Backer, J. M., Myers, M. G. Jr,Shoelson, S. E., Chin, D. J. et al., Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation. EMBO J. 1992, 11, 3469-3479.
33. Draznin, B., Molecular mechanisms of insulin resistance: Serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: The two sides of a coin. Diabetes 2006, 55, 2392-2397.
34. Sklan, E. H., Podoly, E., Soreq, H., RACK1 has the nerve to act: Structure meets function in the nervous system. Prog. Neurobiol. 2006, 78, 117-134.
35. Castle, A., Castle, D., Ubiquitously expressed secretory carrier membrane proteins (SCAMPs) 1-4 mark different pathways and exhibit limited constitutive trafficking to and from the cell surface. J. Cell. Sci. 2005, 118, 3769-3780.
36. Bourges, I., Ramus, C., Mousson de Camaret, B., Beugnot, R. et al., Structural organization of mitochondrial human complex I: Role of the ND4 and ND5 mitochondria-encoded subunits and interaction with prohibitin. Biochem. J. 2004, 383, 491-499.
37. Yen, M. Y., Wang, A. G., Wei, Y. H., Leber's hereditary optic neuropathy: A multifactorial disease. Prog. Retin. Eye Res. 2006, 25, 381-396.
38. Vanniarajan, A., Rajshekher, G. P., Joshi, M. B., Reddy, A. G. et al., Novel mitochondrial mutation in the ND4 gene associated with Leigh syndrome. Acta Neurol. Scand. 2006, 114, 350-353.
39. Andrews, Z. B., Diano, S., Horvath, T. L., Mitochondrial uncoupling proteins in the CNS: In support of function and survival. Nat. Rev. Neurosci. 2005, 6, 829-840.
40. Trenker, M., Malli, R., Fertschai, I., Levak-Frank, S., Graier, W. F., Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2 + uniport. Nat. Cell Biol. 2007, 9, 445-452.
41. Eskelinen, E. L., Tanaka, Y., Saftig, P., At the acidic edge: Emerging functions for lysosomal membrane proteins. Trends Cell Biol. 2003, 13, 137-145.
42. Saitoh, O., Wang, W. C., Lotan, R., Fukuda, M., Differential glycosylation and cell surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinct metastatic potentials. J. Biol. Chem. 1992, 267, 5700-5711.
43. Sun, K. H., Liu, W. T., Tang, S. J., Tsai, C. Y. et al., The expression of acidic ribosomal phosphoproteins on the surface membrane of different tissues in autoimmune and normal mice which are the target molecules for anti-double- stranded DNA antibodies. Immunology 1996, 87, 362-371.
44. Tchorzewski, M., The acidic ribosomal P proteins. Int. J. Biochem. Cell Biol. 2002, 34, 911-915.