Forces determining the adsorption of a monoclonal antibody onto an aluminium hydroxide adjuvant: Influence of interstitial fluid components

Vaccine

Volumn 27, Issue 12, 2009, Pages 1834-1840

  Wolff, Lena ^a,c   Flemming, Jens ^a   Schmitz, Reinhard ^a   Gröger, Karsten ^a   Goso, Cristina ^b   Müller Goymann, Christel ^c  

^a Berlin Chemie AG   (Germany)

^b Menarini Ricerche SpA   (Italy)

^c TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

Abagovomab; Adsorption; Aluminium containing adjuvants

Indexed keywords

ABAGOVOMAB; ALUMINUM HYDROXIDE; ANTIIDIOTYPIC ANTIBODY; PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ADSORPTION; DRUG FORMULATION; ELECTROCHEMISTRY; ELUTION; HYDROPHOBICITY; INTERSTITIAL FLUID; IONIC STRENGTH; ISOELECTRIC FOCUSING; PH; PRIORITY JOURNAL; SIMULATION;

ADJUVANTS, IMMUNOLOGIC; ADSORPTION; ALUMINUM HYDROXIDE; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; CANCER VACCINES; ELECTROCHEMISTRY; ENZYME-LINKED IMMUNOSORBENT ASSAY; ETHYLENE GLYCOL; EXTRACELLULAR FLUID; HUMANS; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; ISOELECTRIC FOCUSING; THERMODYNAMICS;

EID: 61349141174     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.01.037     Document Type: Article

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