Burning mouth syndrome and saliva: Detection of salivary trace elements and cytokines

Journal of Oral Pathology and Medicine

Volumn 38, Issue 3, 2009, Pages 269-275

  Pekiner, F N ^a   Gumru B ^a   Demirel, G Y ^b   Ozbayrak S ^a  

^a MARMARA UNIVERSITY   (Turkey)

^b Centro Laboratories   (Turkey)

Author keywords

Anxiety; Burning mouth syndrome; Cytokines; Magnesium; Saliva; Trace elements

Indexed keywords

COPPER; INTERLEUKIN 2; INTERLEUKIN 6; MAGNESIUM; ZINC;

ADULT; ANXIETY; ARTICLE; BURNING MOUTH SYNDROME; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; FEMALE; HUMAN; MALE; PATHOGENESIS; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; SALIVA ANALYSIS; SALIVA LEVEL; SALIVATION; STATE TRAIT ANXIETY INVENTORY; XEROSTOMIA;

ANXIETY; BURNING MOUTH SYNDROME; CASE-CONTROL STUDIES; COPPER; DEPRESSION; FEMALE; HUMANS; INTERLEUKIN-2; INTERLEUKIN-6; MAGNESIUM; MALE; MIDDLE AGED; PSYCHOMETRICS; SALIVA; TRACE ELEMENTS; XEROSTOMIA; ZINC;

EID: 61349138356     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2008.00734.x     Document Type: Article

References (66)

1. Merskey H, Bogduk N. Classification of chronic pain. Description of chronic pain, pain syndromes and definition of pain terms. Seattle : IASP Press, 1994.
2. Maltsman-Tseikhin A, Moricca P, Niv D. Burning mouth syndrome: will better understanding yield better management? Pain Pract 2007 7 : 151 62.
3. Grushka M, Kawalec J, Epstein JB. Burning mouth syndrome: evolving concepts. Oral Maxillofac Surg Clin North Am 2000 12 : 287 95.
4. Barker KE, Savage NW. Burning mouth syndrome: an update on recent findings. Aust Dent J 2005 50 : 220 3.
5. Pedersen AM, Smidt D, Nauntofte B, Christiani CJ, Jerlang BB. Burning mouth syndrome: etiopathogenic mechanisms, symptomatology, diagnosis and therapeutic approaches. Oral Biol Sci Med 2004 1 : 3 19.
6. Scala A, Checchi L, Montevecchi M, Marini I, Giamberardino MA. Update on burning mouth syndrome: overview and patient management. Crit Rev Oral Biol Med 2003 14 : 275 91.
7. Demarosi F, Tarozzi M, Lodi G, Canegallo L, Rimondini L, Sardella A. The effect of levosulpiride in burning mouth syndrome. Minerva Stomatol 2007 56 : 21 6.
8. Gorsky M, Silverman S JR, Chinn H. Clinical characteristics and management outcome in the burning mouth syndrome. An open study of 130 patients. Oral Surg Oral Med Oral Pathol 1991 72 : 192 5.
9. Lamey PJ, Lamb AB. Prospective study of aetiological factors in burning mouth syndrome. Br Med J 1988 296 : 1243 6.
10. Suarez P, Clark GT. Burning mouth syndrome: an update on diagnosis and treatment methods. J Calif Dent Assoc 2006 34 : 611 22.
11. Woda A, Pionchon P. A unified concept of idiopathic orofacial pain: clinical features. J Orofac Pain 1999 13 : 172 84.
12. Grushka M, Sessle BJ, Miller R. Pain and personality profiles in burning mouth syndrome. Pain 1987 28 : 155 67.
13. Grushka M. Clinical features of burning mouth syndrome. Oral Surg Oral Med Oral Pathol 1987 63 : 30 6.
14. Paterson AJ, Lamb AB, Clifford TJ, Lamey PJ. Burning mouth syndrome: the relationship between the HAD scale and parafunctional habits. J Oral Pathol Med 1995 24 : 289 92.
15. Mignogna MD, Fedele S, Lo Russo L, Leuci S, Lo Muzio L. The diagnosis of burning mouth syndrome represents a challenge for clinicians. J Orofac Pain 2005 19 : 168 73.
16. Simcic D, Pezelj-Ribaric S, Grzic R, Horvat J, Brumini G, Muhvic-Urek M. Detection of salivary interleukin 2 and interleukin 6 in patients with burning mouth syndrome. Mediators Inflamm 2006 2006 (Suppl. 1 54632.
17. Sardella A, Lodi G, Demarosi F, Uglietti D, Carrassi A. Causative or precipitating aspects of burning mouth syndrome: a case-control study. J Oral Pathol Med 2006 35 : 466 71.
18. Pinto A, Sollecito TP, Derossi SS. Burning mouth syndrome. A retrospective analysis of clinical characteristics and treatment outcomes. NY State Dent J 2003 69 : 18 24.
19. Bergdahl M, Bergdahl J. Low unstimulated salivary flow and subjective oral dryness: association with medication, anxiety, depression, and stress. J Dent Res 2000 79 : 1652 8.
20. Vucicevic-Boras V, Topic B, Zadro R, Stavljenic-Rukavina A. Quantity of salivary immunoglobulin A, lysozyme and magnesium in patients with burning mouth syndrome and xerostomia. Acta Stomatol Croat 2001 35 : 211 4.
21. Bergdahl M, Bergdahl J. Burning mouth syndrome: prevalence and associated factors. J Oral Pathol Med 1999 28 : 350 4.
22. Femiano F, Gombos F, Scully C. Burning mouth syndrome: open trial of psychotherapy alone, medication with alpha-lipoic acid (thioctic acid), and combination therapy. Med Oral 2004 9 : 8 13.
23. Savage NW. Burning mouth syndrome: patient management. Aust Dent J 1996 41 : 363 6.
24. Chimenos-Kustner E, Marques-Soares MS. Burning mouth and saliva. Med Oral 2002 7 : 244 53.
25. Syrjanen S, Piironen P, Yli-Urpo A. Salivary content of patients with subjective symptoms resembling galvanic pain. Oral Surg Oral Med Oral Pathol 1984 58 : 387 93.
26. Lamey PJ, Murray BM, Eddie SA, Freeman RE. The secretion of parotid saliva as stimulated by 10% citric acid is not related to precipitating factors in burning mouth syndrome. J Oral Pathol Med 2001 30 : 121 4.
27. Soares MS, Chimenos-Küstner E, Subirá-Pifarrè C, Rodríguez De Rivera-Campillo ME, López-López J. Association of burning mouth syndrome with xerostomia and medicines. Med Oral Patol Oral Cir Bucal 2005 10 : 301 8.
28. Lundy FT, Al-Hashimi I, Rees TD, Lamey PJ. Evaluation of major parotid glycoproteins in patients with burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997 83 : 252 8.
29. Tammiala-Salonen T, Söderling E. Protein composition, adhesion, and agglutination properties of saliva in burning mouth syndrome. Scand J Dent Res 1993 101 : 215 8.
30. Granot M, Nagler RM. Association between regional idiopathic neuropathy and salivary involvement as the possible mechanism for oral sensory complaints. J Pain 2005 6 : 581 7.
31. Schlegel-Zawadzka M, Zieba A, Dudek D, Zak-Knapik J, Nowak G. Is serum copper a "trait marker" of unipolar depression? A preliminary clinical study. Pol J Pharmacol 1999 51 : 535 8.
32. Banki CM, Vojnik M, Papp Z, Balla KZ, Arató M. Cerebrospinal fluid magnesium and calcium related to amine metabolites, diagnosis, and suicide attempts. Biol Psychiatry 1985 20 : 163 71.
33. Galland L. Magnesium and inflammatory bowel disease. Magnesium 1988 7 : 78 83.
34. Maes M, De Vos N, Demedts P, Wauters A, Neels H. Lower serum zinc in major depression in relation to changes in serum acute phase proteins. J Affect Disord 1999 56 : 189 94.
35. Anisman H, Merali Z, Poulter MO, Hayley S. Cytokines as a precipitant of depressive illness: animal and human studies. Curr Pharm Des 2005 11 : 963 72.
36. Anisman H, Merali Z. Cytokines, stress and depressive illness: brain-immune interactions. Ann Med 2003 35 : 2 11.
37. Pekiner FN, Demirel GY, Gumru B, Ozbayrak S. Serum cytokine and T regulatory cell levels in patients with burning mouth syndrome. J Oral Pathol Med 2008 37 : 528 34.
38. Xia J, Lin M, Jin Z. Correlations among mood disorder, serum interleukin-2 and interleukin-6 in patients with burning mouth syndrome. Hua Xi Kou Qiang Yi Xue Za Zhi 2003 21 : 377 8.
39. Lamey PJ, Freeman R, Eddie SA, Pankhurst C, Rees T. Vulnerability and presenting symptoms in burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005 99 : 48 54.
40. Eli I, Kleinhauz M, Baht R, Littner M. Antecedents of burning mouth syndrome (glossodynia) - recent life events vs. psychopathologic aspects. J Dent Res 1994 73 : 567 72.
41. Pekiner FN, Gumru B, Ozbayrak S. Efficacy of moclobemide in burning mouth syndrome: a nonrandomized, open-label study. J Orofac Pain 2008 22 : 146 52.
42. Fenoll-Palomares C, Muñoz-Montagud JV, Sanchiz V, et al. Unstimulated salivary flow rate, pH and buffer capacity of saliva in healthy volunteers. Rev Esp Enferm Dig 2004 96 : 773 83.
43. Watanabe M, Asatsuma M, Ikui A, et al. Measurements of several metallic elements and matrix metalloproteinases (MMPs) in saliva from patients with taste disorder. Chem Senses 2005 30 : 121 5.
44. Burguera-Pascu M, Rodríguez-Archilla A, Baca P. Substantivity of zinc salts used as rinsing solutions and their effect on the inhibition of Streptococcus mutans. J Trace Elem Med Biol 2007 21 : 92 101.
45. Zung WW. A self-rating depression scale. Arch Gen Psychiatry 1965 12 : 63 70.
46. Pekiner FN, Ozbayrak S, Canakci E. Burning mouth syndrome in patients wearing protheses: evaluation of type I and type II. The Pain Clinic 2005 17 : 269 73.
47. Zhao M, Chen Q, Lin M. Relationship between the symptom of xerostomia and non-stimulated salivary flow rates in patients with burning mouth syndrome. Hua Xi Kou Qiang Yi Xue Za Zhi 2001 19 : 169 70.
48. Glick D, Ben-Aryeh H, Gutman D, Szargel R. Relation between idiopathic glossodynia and salivary flow rate and content. Int J Oral Surg 1976 5 : 161 5.
49. De Moura SA, De Sousa JM, Lima DF, Negreiros AN, Silva Fde V, Da Costa LJ. Burning mouth syndrome (BMS): sialometric and sialochemical analysis and salivary protein profile. Gerodontology 2007 24 : 173 6.
50. Eby GA, Eby KL. Rapid recovery from major depression using magnesium treatment. Med Hypotheses 2006 67 : 362 70.
51. Hashizume N, Mori M. An analysis of hypermagnesemia and hypomagnesemia. Jpn J Med 1990 29 : 368 72.
52. Siwek M, Wrobel A, Dudek D, Nowak G, Zieba A. The role of copper and magnesium in the pathogenesis and treatment of affective disorders. Psychiatr Pol 2005 39 : 911 20.
53. Al Quran FA. Psychological profile in burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004 97 : 339 44.
54. Van Der Ploeg HM, Van Der Wal N, Eijkman MA, Van Der Waal I. Psychological aspects of patients with burning mouth syndrome. Oral Surg Oral Med Oral Pathol 1987 63 : 664 8.
55. Feinmann C, Harris M, Cawley R. Psychogenic facial pain: presentation and treatment. Br Med J 1984 288 : 436 8.
56. Kronfol Z, Remick DG. Cytokines and the brain: implications for clinical psychiatry. Am J Pyschiatry 2000 157 : 683 94.
57. Maes M, Bosmans E, Meltzer HY, Scharpé S, Suy E. Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression? Am J Psychiatry 1993 150 : 1189 93.
58. Maes M, Meltzer HY, Bosmans E, et al. Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. J Affect Disord 1995 34 : 301 9.
59. Weizman R, Laor N, Podliszewski E, Notti I, Djaldetti M, Bessler H. Cytokine production in major depressed patients before and after clomipramine treatment. Biol Psychiatry 1994 35 : 42 7.
60. Rothwell NJ, Hopkins SJ. Cytokines and the nervous system II: Actions and mechanisms of action. Trends Neurosci 1995 18 : 130 6.
61. Rhodus NL, Cheng B, Myers S, Ho V, Ondrey F. NFkappaB dependent cytokines in different oral fluids from patients with oral lichen planus. J Clin Immunol 2005 97 : 231 7.
62. Anisman H, Kokkinidis L, Merali Z. Further evidence for the depressive effects of cytokines: anhedonia and neurochemical changes. Brain Behav Immun 2002 16 : 544 56.
63. Yamano S, Atkinson JC, Baum BJ, Fox PC. Salivary gland cytokine expression in NOD and normal BALB/c mice. Clin Immunol 1999 92 : 265 75.
64. O'brien SM, Scott LV, Dinan TG. Cytokines: abnormalities in major depression and implications for pharmacological treatment. Hum Psychopharmacol 2004 19 : 397 403.
65. Vucicevic-Boras V, Brailo V, Lukac J, Kordic D, Blazic-Potocki Z. Salivary interleukin-6 and tumor necrosis factor-α in patients with burning mouth syndrome. Oral Dis 2006 12 : 353 5.
66. Chen Q, Xia J, Lin M, Zhou H, Li B. Serum interleukin-6 in patients with burning mouth syndrome and relationship with depression and perceived pain. Mediators Inflamm 2007 2007 : 45327.