Detection of MAGE-1 MAGE-3 and AFP mRNA as multimarker by real-time quantitative PCR assay: A possible predictor of hematogenous micrometastasis of hepatocellular carcinoma

Hepato-Gastroenterology

Volumn 55, Issue 88, 2008, Pages 2200-2206

  Zhang, Yuqing ^a   Li, Qiang ^a   Liu, Ning ^a   Song, Tianqiang ^a   Liu, Zhisheng ^a   Guo, Rende ^a   Meng, Lingxin ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

AFP; Hepatocellular carcinoma; MAGE 1; MAGE 3; Micrometastasis; Real time Q PCR

Indexed keywords

ALPHA FETOPROTEIN; MELANOMA ANTIGEN 1; MELANOMA ANTIGEN 3; MESSENGER RNA; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER STAGING; CHRONIC LIVER DISEASE; CONTROLLED STUDY; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; MICROMETASTASIS; PORTAL VEIN THROMBOSIS; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TUMOR DIFFERENTIATION; TUMOR VOLUME; VOLUNTEER;

ADULT; AGED; ALPHA-FETOPROTEINS; ANTIGENS, NEOPLASM; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE OF TESTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 60849135133     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Parkin DM, Bray F, Ferlay J, et al. Global Cancer Statistics. CA Cancer J Clin 2005; 55:74-108.
2. Llovet JM, Fuster J, Bruix J. Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation. Hepatology 1999; 30:1434-1440.
3. Lam CM, Lo CM, Yuen WK, et al. Prolonged survival in selected patients following surgical resection for pulmonary metastasis from hepatocellular carcinoma. Br J Surg 1998; 85:1198-1200.
4. Schlitt HJ, Neipp M, Weimann A, et al. Recurrence patterns of hepatocellular and fibrolamellar carcinoma after liver transplantation. J Clin Oncol 1999;17:324-331.
5. Yamamoto J, Kosuge T, Takayama T, et al. Recurrence of hepatocellular carcinoma after surgery. Br J Surg 1996; 83:1219-1222.
6. Tang ZY, Zhou XD, Lin ZY, et al. Surgical treatment of hepatocellular carcinoma and related basic research with special reference to recurrence and metastasis. Chin Med J 1999; 112: 887-891.
7. Arvelo F, Poupon MF. Molecular and cell aspects of the cancer metastasis. Acta Cient Venez 2001; 52:304-312.
8. Sakon M,Nagano H,Nakamori S, et al. Intrahepatic recurrences of hepatocellula carcinoma afterhepatectomy: analysis based on tumor hemodynamics. Arch Surg 2002; 137: 94-99.
9. Hillaire S, Barbu V, Boucher E, et al. Albumin messenger RNA as a marker of circulating hepatocytes in hepatocelular carcinoma. Gastroenterology 1994; 106:239-242.
10. Ijichi M, Takayama T, Matsumura M, et al. Alpha-tetoprotein mRNA in the circulation as a predictor of postsurgical recurrence of hepatocellular carcinoma: a prospective study. Hepatology 2002; 35:853-860.
11. Chou HC, Sheu JC, Huang GT, et al. Albumin messenger RNA is not specific for circulating hepatoma cells. Gastro-enterology 1994; 107:630-631.
12. Cillo U,Naraglia F,Vitale A, et al. Clinical significance of alpha-fetoprotein mRNA in blood of patients with hepatocellual carcinoma. Clin Chim Acta 2004; 347:129-138.
13. De-Plaen E, Arden K, Traversal C, et al. Structure, chromosomal localization, and expression of 12 genes of the MAGE family. Immunogenetics 1994; 40:360-369.
14. Yang SZ, Dong JH, Li K, et al. Detection of AFPmRNA and melanoma antigen gene-1mRNA as markers of disseminated hepatocellularcarcinoma cells in blood. Hepatobiliary Pancreat Dis Int 2005; 4:227-233.
15. Miyamoto A, Fujiwara Y, Sakon M, et al. Development of a multiple-marker RT-PCR assay for detection of micro-metastases of hepatocellular carcinoma. Dig Dis Sci 2000; 45:1376-1382.
16. Mou DC, Cai SL, Peng JR, et al. Evaluation of MAGE-1 and MAGE-3 as tumour-specific markers to detect blood dissemination of hepatocellular carcinoma cells. Br J Cancer 2002; 86:110-116.
17. Pantel K, Schlimok G, Kutter D, et al. Frequent down-regulation of major histocompatibility class I antigen expression on individual micrometastatic carcinoma cells. Cancer Res 1991; 51:4712-4715.
18. Pelosi G, Pastorino U, Pasini F, et al. Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer. Br J Cancer 2003; 88:537-547.
19. Kufer P, Zippelius A, Lutterbuse R, Mecklenburg I, Enzmann T, Montag A, et al. Heterogeneous expression of MAGE-A genes in occult disseminated tumor cells: a novel multimarker reverse transcription-polymerase chain reaction for diagnosis of micrometastatic disease. Cancer Res 2002; 62:251-261.
20. Sher YP, Shih JY, Yang PC, et al. Prognosis of non-small cell lung cancer patients by detecting circulating cancer cells in the peripheral blood with multiple marker genes. Clin Cancer Res 2005; 11:173-179.
21. Jeng KS, Sheen IS, Tsai YC. Does the presence of circulating hepatocellular carcinoma cells indicate a risk of recurrence after resection? Am J Gastroenterol 2004; 99:1503-1509.
22. Morimoto O, Nagano H, Miyamoto A, et al. Association between recurrence of hepatocellular carcinoma and alpha-fetoprotein messenger RNA levels in peripheral blood. Surg Today 2005; 35:1033-1041.
23. Miyashiro I, Kuo C, Huynh K, et al. Molecular strategy for detecting metastatic cancers with use of multiple tumor-specific MAGE-A genes. Clin Chem 2001; 47:505-512.
24. Wang YL, Li G, Wu D, et al. Analysis of alpha-fetoprotein mRNA level on the tumor cell hematogenous spread of patients with hepatocellular carcinoma undergoing orthotopic liver transplantation. Transplant Proc 2007; 39:166-168.
25. Yanaga K. Current status of hepatic resection for hepato-cellular carcinoma. J Gastroenterol 2004; 39: 919-26.
26. Imamura H, Matsuyama Y, Tanaka E, et al. Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy. J Hepatol 2003; 38: 200-207.
27. Pfleiderer C, Zoubek A, Gruber B, et al. Detection of tumor cells in peripheral blood and bone marrow from Ewing tumor patients by RT-PCR. Int J Cancer 1995; 64:135-139.
28. Matsumura M, Niwa Y, Kato N, et al. Detection of α-Fetoprotein mRNA, an indicator of hematogenous spreading hepatocellar carcinoma, in the circulation: a possible predictor of metastatic hepatocellular carcinoma. Hepatology 1994; 20:1418-1425.
29. Komeda T, Pukuda Y, Sando T, et al. Sensitive detection of circulating hepatocellular carcinoma cells in peripheral venous blood. Cancer 1995; 75:2214-2219.
30. Kedda MA, Kew MC, Skelton M, et al. Non-specificity of messenger RNA of alpha- fetoprotein in peripheral blood in detecting early spread of hepatocellular carcinoma in black Africans. J Gastroenterol Hepatol 1998; 13:885-891.
31. Funaki NO, Tanaka J, Seto SI, et al. Hematogenous spreading of hepatocellular carcinoma cells: possible participation in recurrence in the liver. Hepatology 1997; 25:564-568.
32. Yuasa T, Okamoto K, Kawakami T et al. Expression patterns of cancer testis antigens in testicular germ cell tumors and adjacent testicular tissue. J Urol 2001; 165:1790-1794.
33. Tahara K, Mori M, Sadanaga N, et al. Expression of the MAGE gene family in human hepatocellular carcinoma. Cancer 1999; 85:1234-1240.