Design, synthesis of 8-alkoxy-5,6-dihydro-[1,2,4]triazino[4,3-a]quinolin-1-ones with anticonvulsant activity

European Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2009, Pages 1265-1270

  Sun, Xian Yu ^a   Zhang, Lei ^a   Wei, Cheng Xi ^a   Piao, Hu Ri ^a   Quan, Zhe Shan ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

1,2,4 Triazino 4,3 a quinolin 1 one; 3 Mercaptopropionic acid; Anticonvulsant; Isoniazid; MES; Pentylenetetrazole; Strychnine; Thiosemicarbazide; Triazone

Indexed keywords

8 ALKOXY 5,6 DIHYDRO [1,2,4]TRIAZINO[4,3 A]QUINOLIN 1 ONE DERIVATIVE; 8 HEPTYLOXY 5,6 DIHYDRO [1,2,4]TRIAZINO[4,3 A]QUINOLIN 1 ONE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; MOUSE; NEUROTOXICITY; NONHUMAN; SEIZURE;

ANTICONVULSANTS; DRUG DESIGN; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; QUINOLONES; SPECTROPHOTOMETRY, INFRARED;

EID: 60849119528     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.09.003     Document Type: Article

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