Synthesis and anticonvulsant activity of 7-alkoxyl-4,5-dihydro-[1,2,4] triazolo[4,3-a]quinolines

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 21, 2005, Pages 4803-4805

  Xie, Zhi Feng ^a   Chai, Kyu Yun ^b   Piao, Hu Ri ^a   Kwak, Kyung Chell ^b   Quan, Zhe Shan ^a  

^a YANBIAN UNIVERSITY   (China)

^b Wonkwang University   (South Korea)

Author keywords

1,2,4 Triazolo 4,3 a quinolines; Anticonvulsant; Maximal electroshock; Neurotoxicity; Pentylenetetrazol

Indexed keywords

6 HYDROXY 3,4 DIHYDRO 1H QUINOLIN 2 ONE; 7 (4 FLUOROBENZYLOXY) 4,5 DIHYDRO[1,2,4]TRIAZOLO[4,3 A]QUINOLINE; ANTICONVULSIVE AGENT; PENTETRAZOLE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CONVULSION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ELECTRIC SHOCK; MOUSE; NEUROTOXICITY; NONHUMAN; ROTAROD TEST;

ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; MICE; NEUROTOXICITY SYNDROMES; QUINOLINES; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 25144491192     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.051     Document Type: Article

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