Noninvasive imaging of transplanted cells

Current Opinion in Organ Transplantation

Volumn 13, Issue 6, 2008, Pages 654-658

  Modo, Michel ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Bioluminescence; Cell transplant; Cellular imaging; MRI; Optical imaging; Positron emission tomography; Single photon emission computed tomography; Transplantation; Ultrasound

Indexed keywords

CELL FATE; CELL TRANSPLANTATION; CELLULAR DISTRIBUTION; HUMAN; IMAGING SYSTEM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ANIMAL; DIAGNOSTIC IMAGING; ECHOGRAPHY; FLUORESCENCE MICROSCOPY; IMAGE PROCESSING; METHODOLOGY; REPORTER GENE; STAINING;

CONTRAST MEDIUM; FLUORESCENT DYE;

ANIMALS; CELL TRANSPLANTATION; CONTRAST MEDIA; DIAGNOSTIC IMAGING; FLUORESCENT DYES; GENES, REPORTER; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MICROSCOPY, FLUORESCENCE; POSITRON-EMISSION TOMOGRAPHY; STAINING AND LABELING; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; ULTRASONOGRAPHY;

EID: 60849094842     PISSN: 10872418     EISSN: 15317013     Source Type: Journal    
DOI: 10.1097/MOT.0b013e328317a43c     Document Type: Review

References (45)

1. Modo M, Hoehn M, Bulte JW. Cellular MR imaging. Mol Imaging 2005; 4:143-164.
2. Arbab AS, Yocum GT, Kalish H, et al. Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood 2004; 104:1217-1223.
3. Walczak P, Kedziorek DA, Gilad AA, et al. Instant MR labeling of stem cells using magnetoelectroporation. Magn Reson Med 2005; 54:769-774.
4. Brekke C, Morgan SC, Lowe AS, et al. The in vitro effects of a bimodal contrast agent on cellular functions and relaxometry. NMR Biomed 2007; 20:77-89.
5. Modo M, Beech JS, Meade TJ, et al. A chronic 1 year assessment of MRI contrast agent-loaded neural stem cell transplants in stroke. Neuroimage (in press). doi: 10.101 6/j.neuroimage.2008.06.01 7.
6. Pawelczyk E, Arbab AS, Chaudhry A, et al. In vitro model of bromodeoxyur-idineor iron oxide nanoparticle uptake by activated macrophages from labeled stem cells: implications for cellular therapy. Stem Cells 2008; 26:1366-1375.
7. Choi D, Kim JH, Lim M, et al. Hepatocyte-like cells from human mesenchymal stem cells engrafted in regenerating rat liver tracked with in vivo magnetic resonance imaging. Tissue Eng Part C Methods 2008; 14:15-23.
8. Ju S, Teng GJ, Lu H, et al. In vivo MR tracking of mesenchymal stem cells in rat liver after intrasplenic transplantation. Radiology 2007; 245:206-215.
9. Sun JH, Teng GJ, Ju SH, et al. MR tracking of magnetically labeled mesenchymal stem cells in rat kidneys with acute renal failure. Cell Transplant 2008; 17:279-290.
10. Cai J, Zhang X, Wang X, et al. In vivo MR imaging of magnetically labeled mesenchymal stem cells transplanted into rat liver through hepatic arterial injection. Contrast Media Mol Imag 2008; 3:61-66.
11. Barnett BP, Arepally A, Karmarkar PV, et al. Magnetic resonance-guided, realtime targeted delivery and imaging of magnetocapsules immunoprotecting pancreatic islet cells. Nat Med 2007; 13:986-991.
12. de Vries IJ, Lesterhuis WJ, Barentsz JO, et al. Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 2005; 23:1407-1413.
13. Wirth EDr, Reier PJ, Fessler RG, et al. Feasibility and safety of neural tissue transplantation in patients with syringomyelia. J Neurotrauma 2001; 18:911-929.
14. Carr CA, Stuckey DJ, Tatton L, et al. Bone marrow-derived stromal cells home to and remain in the infarcted rat heart, but fail to improve function: an in vivo cine MRI study. Am J Physiol Heart Circ Physiol 2008; 295:H533-H542.
15. Roberts TJ, Price J, Williams SC, Modo M. Pharmacological MRI of stem cell transplants in the 3-nitropropionic acid-damaged striatum. Neuroscience 2007; 144:100-109.
16. Roberts TJ, Price J, Williams SC, Modo M. Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease. Neuroscience 2006; 139:1187-1199.
17. Manganas LN, Zhang X, Li Y, et al. Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science 2007; 318:980-985.
18. Jansen JF, Shamblott MJ, van Zijl PC, et al. Stem cell profiling by nuclear magnetic resonance spectroscopy. Magn Reson Med 2006; 56:666-670.
19. Cohen B, Ziv K, Plaks V, et al. MRI detection of transcriptional regulation of gene expression in transgenic mice. Nat Med 2007; 13:498-503.
20. Genove G, DeMarco U, Xu H, et al. A new transgene reporter for in vivo magnetic resonance imaging. Nat Med 2005; 11:450-454.
21. Piccini P, Lindvall O, Bjorklund A, et al. Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts. Ann Neurol 2000; 48:689-695.
22. Huang J, Lee CC, Sutcliffe JL, et al. Radiolabeling rhesus monkey CD34(+) hematopoietic and mesenchymal stem cells with (64)Cu-Pyruvaldehyde- Bis(N4-methylthiosemicarbazone) for MicroPET imaging. Mol Imaging 2008; 7:1-11.
23. Lappalainen RS, Narkilahti S, HuhtalaT, et al. The SPECT imaging shows the accumulation of neural progenitor cells into internal organs after systemic administration in middle cerebral artery occlusion rats. Neurosci Lett 2008; 440:246-250.
24. Stodilka RZ, Blackwood KJ, Prato FS. Tracking transplanted cells using dualradionuclide SPECT. Phys Med Biol 2006; 51:2619-2632.
25. Jin Y, Kong H, Stodilka RZ, et al. Determining the minimum number of detectable cardiac-transplanted 111In-tropolone-labelled bone-marrow-derived mesenchymal stem cells by SPECT. Phys Med Biol 2005; 50: 4445-4455.
26. Stodilka RZ, Blackwood KJ, Kong H, Prato FS. A method for quantitative cell tracking using SPECT for the evaluation of myocardial stem cell therapy. Nucl Med Commun 2006; 27:807-813.
27. Acton PD, Zhou R. Imaging reporter genes for cell tracking with PET and SPECT. Q J Nucl Med Mol Imaging 2005; 49:349-360.
28. Kang JH, Lee DS, Paeng JC, et al. Development of a sodium/iodide symporter (NIS)-transgenic mouse for imaging of cardiomyocyte-specific reporter gene expression. J Nucl Med 2005; 46:479-483.
29. Tran N, Franken PR, Maskali F, et al. Intramyocardial Implantation of bone marrow-derived stem cells enhances perfusion in chronic myocardial infarction: dependency on initial perfusion depth and follow-up assessed by gated pinhole SPECT. J Nucl Med 2007; 48:405-412.
30. Zhou R, Thomas DH, Qiao H, et al. In vivo detection of stem cells grafted in infarcted rat myocardium. J Nucl Med 2005; 46:816-822.
31. Weller GE, Lu E, Csikari MM, et al. Ultrasound imaging of acute cardiac transplant rejection with microbubbles targeted to intercellular adhesion molecule-1. Circulation 2003; 108:218-224.
32. Kondo I, Ohmori K, Oshita A, et al. Leukocyte-targeted myocardial contrast echocardiography can assess the degree of acute allograft rejection in a rat cardiac transplantation model. Circulation 2004; 109:1056-1061.
33. Von Buttlar M, Twerdowski E, Wannemacher R, Grill W. Noninvasive monitoring of mesenchymal stem cells by 1.2 GHz acoustic microscopy. J Acoust Soc Am 2008; 123:3915.
34. Kim K, Jeong CG, Hollister SJ. Noninvasive monitoring of tissue scaffold degradation using ultrasound elasticity imaging. Acta Biomater 2008; 4:783-790.
35. Weir C, Morel-Kopp MC, Gill A, et al. Mesenchymal stem cells: isolation, characterisation and in vivo fluorescent dye tracking. Heart Lung Circ 2008; 17:395-403.
36. Muller-Borer BJ, Collins MC, Gunst PR, et al. Quantum dot labeling of mesenchymal stem cells. J Nanobiotechnol 2007; 5:9.
37. Gao X, Chung LW, Nie S. Quantum dots for in vivo molecular and cellular imaging. Methods Mol Biol 2007; 374:135-145.
38. Pinaud F, Michalet X, Bentolila LA, et al. Advances in fluorescence imaging with quantum dot bio-probes. Biomaterials 2006; 27:1679-1687.
39. Kim D-E, Schellingerhout D, Ishii K, et al. Imaging of stem cell recruitment to ischemic infarcts in a murine model. Stroke 2004; 35:952-957.
40. Swijnenburg RJ, Schrepfer S, Cao F, et al. In vivo imaging of embryonic stem cells reveals patterns of survival and rejection following transplantation. Stem Cells Dev 2008. doi: 10.1089/scd.2008.0091. [Epub ahead of print]
41. Couillard-Despres S, Finkl R, Winner B, et al. In vivo optical imaging of neurogenesis: watching new neurons in the intact brain. Mol Imaging 2008; 7:28-34.
42. Shah K, Hingtgen S, Kasmieh R, et al. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci 2008; 28:4406-4413.
43. Huinink HP, Sanders HM, Erich SJ, et al. High-resolution NMR imaging of paramagnetic liposomes targeted to a functionalized surface. Magn Reson Med 2008; 59:1282-1286.
44. Modo M, Cash D, Mellodew K, et al. Tracking transplanted stem cell migration using bifunctional, contrast agent-enhanced, magnetic resonance imaging. Neuroimage 2002; 17:803-811.
45. Walczak P, Zhang J, Gilad AA, et al. Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke 2008; 39:1569-1574.