Phase II trial of neoadjuvant docetaxel and gefitinib followed by radical prostatectomy in patients with high-risk, locally advanced prostate cancer

Cancer

Volumn 115, Issue 4, 2009, Pages 784-791

  Vuky, Jacqueline ^a   Porter, Christopher ^a   Isacson, Christina ^a   Vaughan, Matthew ^a   Kozlowski, Paul ^a   Picozzi, Vincent ^a   Corman, John ^a  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

Author keywords

Docetaxel; Gefitinib; Neoadjuvant chemotherapy; Pathologic complete response; Prostate cancer

Indexed keywords

ALANINE AMINOTRANSFERASE; DEXAMETHASONE; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEFITINIB; PROSTATE SPECIFIC ANTIGEN;

ABDOMINAL CRAMP; ADULT; ADVANCED CANCER; AGED; ALOPECIA; ANEMIA; ARTICLE; BEDTIME DOSAGE; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER LOCALIZATION; CANCER PATIENT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DRUG DOSE ESCALATION; DRUG DOSE REDUCTION; DRUG TOLERABILITY; DRUG WITHDRAWAL; EVENING DOSAGE; FATIGUE; FEBRILE NEUTROPENIA; GLEASON SCORE; HIGH RISK PATIENT; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER FUNCTION; LIVER FUNCTION TEST; LYMPHADENOPATHY; MALE; MINIMAL RESIDUAL DISEASE; MORNING DOSAGE; MOUTH PAIN; MULTIPLE CYCLE TREATMENT; NEUROPATHY; NEUTROPENIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROSTATECTOMY; RASH; SIDE EFFECT; SKIN TOXICITY; THROMBOCYTOPENIA; TREATMENT RESPONSE;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; FOLLOW-UP STUDIES; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; PROSTATECTOMY; PROSTATIC NEOPLASMS; QUINAZOLINES; RISK FACTORS; TAXOIDS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 60849093184     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24092     Document Type: Article

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