Forced IFIT-2 expression represses LPS induced TNF-alpha expression at posttranscriptional levels

BMC Immunology

Volumn 9, Issue , 2008, Pages

  Berchtold, Susanne ^a   Manncke, Birgit ^a   Klenk, Juliane ^a   Geisel, Julia ^a   Autenrieth, Ingo B ^a   Bohn, Erwin ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GENE PRODUCT; INTERFERON INDUCED TETRATRICOPEPTIDE REPEAT PROTEIN 2; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PROTEIN MIP 2; TETRATRICOPEPTIDE REPEAT PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BETA INTERFERON; CARRIER PROTEIN; CXCL2 CHEMOKINE; CXCL2 PROTEIN, MOUSE; HYBRID PROTEIN; IFIT1 PROTEIN, MOUSE; IFIT2 PROTEIN, MOUSE; MESSENGER RNA; PROTEIN;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; GENE EXPRESSION; GENETIC STABILITY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MACROPHAGE; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECT; GENE DELETION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOUSE; PROTEIN BINDING; PROTEIN SYNTHESIS; REGULATORY RNA SEQUENCE; RNA PROCESSING; RNA STABILITY; SECRETION; TRANSCRIPTION INITIATION; TRANSGENE;

3' UNTRANSLATED REGIONS; ANIMALS; CARRIER PROTEINS; CELL LINE; CHEMOKINE CXCL2; IMMUNITY, INNATE; INTERFERON-BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEINS; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, RIBONUCLEIC ACID; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; SEQUENCE DELETION; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TRANSGENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 60749128384     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-9-75     Document Type: Article

References (38)

1. Kawai T Akira S TLR signaling Cell Death Differ 2006, 13:816-825 16410796
2. Akira S TLR signaling Curr Top Microbiol Immunol 2006, 311:1-16 17048703
3. Sabroe I Parker LC Dower SK Whyte MK The role of TLR activation in inflammation J Pathol 2008, 214:126-135 18161748
4. Deonarain R Verma A Porter AC Gewert DR Platanias LC Fish EN Critical roles for IFN-beta in lymphoid development, myelopoiesis, and tumor development: Links to tumor necrosis factor alpha Proc Natl Acad Sci USA 2003, 100:13453-13458 263835 14597717
5. Zuniga EI Hahm B Oldstone MB Type I interferon during viral infections: multiple triggers for a multifunctional mediator Curr Top Microbiol Immunol 2007, 316:337-357 17969455
6. Mancuso G Midiri A Biondo C Beninati C Zummo S Galbo R Tomasello F Gambuzza M Macri G Ruggeri A Leanderson T Teti G Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria J Immunol 2007, 178:3126-3133 17312160
7. Swann JB Hayakawa Y Zerafa N Sheehan KC Scott B Schreiber RD Smyth MJ Type I IFN contributes to NK cell homeostasis, activation, and antitumor function J Immunol 2007, 178:7540-7549 17548588
8. Crow MK Type I interferon in systemic lupus erythematosus Curr Top Microbiol Immunol 2007, 316:359-386 17969456
9. Weighardt H Kaiser-Moore S Schlautkotter S Rossmann-Bloeck T Schleicher U Bogdan C Holzmann B Type I IFN modulates host defense and late hyperinflammation in septic peritonitis J Immunol 2006, 177:5623-5630 17015750
10. Carrero JA Calderon B Unanue ER Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection J Exp Med 2004, 200:535-540 2211931 15302900
11. Sen GC Sarkar SN The interferon-stimulated genes: Targets of direct signaling by interferons, double-stranded RNA, and viruses Curr Top Microbiol Immunol 2007, 316:233-250 17969451
12. de Veer MJ Holko M Frevel M Walker E Der S Paranjape JM Silverman RH Williams BR Functional classification of interferon-stimulated genes identified using microarrays J Leukoc Biol 2001, 69:912-920 11404376
13. Rani MR Shrock J Appachi S Rudick RA Williams BR Ransohoff RM Novel interferon-beta-induced gene expression in peripheral blood cells J Leukoc Biol 2007, 82:1353-1360 17709400
14. Terenzi F White C Pal S Williams BR Sen GC Tissue-specific and inducer-specific differential induction of ISG56 and ISG54 in mice J Virol 2007, 81:8656-8665 1951374 17553874
15. Handley SA Dube PH Miller VL Histamine signaling through the H(2) receptor in the Peyer's patch is important for controlling Yersinia enterocolitica infection Proc Natl Acad Sci USA 2006, 103:9268-9273 1482599 16717182
16. Bohn E Bechtold O Zahir N Frick JS Reimann J Jilge B Autenrieth IB Host gene expression in the colon of gnotobiotic interleukin-2-deficient mice colonized with commensal colitogenic or noncolitogenic bacterial strains: Common patterns and bacteria strain specific signatures Inflamm Bowel Dis 2006, 12:853-862 16954804
17. Bluyssen HA Vlietstra RJ Faber PW Smit EM Hagemeijer A Trapman J Structure, chromosome localization, and regulation of expression of the interferon-regulated mouse Ifi54/Ifi56 gene family Genomics 1994, 24:137-148 7896268
18. Bluyssen HA Vlietstra RJ van der Made A Trapman J The interferon-stimulated gene 54 K promoter contains two adjacent functional interferon-stimulated response elements of different strength, which act synergistically for maximal interferon-alpha inducibility Eur J Biochem 1994, 220:395-402 8125096
19. Terenzi F Pal S Sen GC Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54 Virology 2005, 340:116-124 16023166
20. Hui DJ Terenzi F Merrick WC Sen GC Mouse p56 blocks a distinct function of eukaryotic initiation factor 3 in translation initiation J Biol Chem 2005, 280:3433-3440 15561726
21. Terenzi F Hui DJ Merrick WC Sen GC Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56 J Biol Chem 2006, 281:34064-34071 16973618
22. Kapasi P Chaudhuri S Vyas K Baus D Komar AA Fox PL Merrick WC Mazumder B L13a blocks 48 S assembly: Role of a general initiation factor in mRNA-specific translational control Mol Cell 2007, 25:113-126 1810376 17218275
23. Mazumder B Sampath P Fox PL Regulation of macrophage ceruloplasmin gene expression: One paradigm of 3′-UTR-mediated translational control Mol Cells 2005, 20:167-172 16267389
24. Sampath P Mazumder B Seshadri V Gerber CA Chavatte L Kinter M Ting SM Dignam JD Kim S Driscoll DM Fox PL Noncanonical function of glutamyl-prolyl-tRNA synthetase: Gene-specific silencing of translation Cell 2004, 119(2):195-208 15479637
25. Stoecklin G Lu M Rattenbacher B Moroni C A constitutive decay element promotes tumor necrosis factor alpha mRNA degradation via an AU-rich element-independent pathway Mol Cell Biol 2003, 23:3506-3515 164766 12724409
26. Stoecklin G Stoeckle P Lu M Muehlemann O Moroni C Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements RNA 2001, 7:1578-1588 1370200 11720287
27. Wax SD Nakamura H Anderson PJ The tumor necrosis factor-alpha AU-rich element inhibits the stable association of the 40 S ribosomal subunit with RNA transcripts Biochem Biophys Res Commun 2005, 333:1100-1106 15967409
28. Mashima R Saeki K Aki D Minoda Y Takaki H Sanada T Kobayashi T Aburatani H Yamanashi Y Yoshimura A FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling J Biol Chem 2005, 280:41289-97 16221674
29. Chen CY Shyu AB AU-rich elements: Characterization and importance in mRNA degradation Trends Biochem Sci 1995, 20:465-470 8578590
30. Carballo E Lai WS Blackshear PJ Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin Science 1998, 281:1001-1005 9703499
31. Dean JL Sully G Clark AR Saklatvala J The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation Cell Signal 2004, 16:1113-1121 15240006
32. Zhang T Kruys V Huez G Gueydan C AU-rich element-mediated translational control: Complexity and multiple activities of trans-activating factors Biochem Soc Trans 2002, 30:952-958 12440953
33. Sheehan KC Lai KS Dunn GP Bruce AT Diamond MS Heutel JD Dungo-Arthur C Carrero JA White JM Hertzog PJ Schreiber RD Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection J Interferon Cytokine Res 2006, 26:804-819 17115899
34. Sheehan KC Calderon J Schreiber RD Generation and characterization of monoclonal antibodies specific for the human IFN-gamma receptor J Immunol 1988, 140:4231-4237 2453573
35. Shaner NC Campbell RE Steinbach PA Giepmans BN Palmer AE Tsien RY Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein Nat Biotechnol 2004, 22:1567-1572 15558047
36. Schulte R Autenrieth IB Yersinia enterocolitica-induced interleukin-8 secretion by human intestinal epithelial cells depends on cell differentiation Infect Immun 1998, 66:1216-1224 108036 9488416
37. Pfaffl MW A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 2001, 29:e45 55695 11328886
38. Schmittgen TD Real-time quantitative PCR Methods 2001, 25:383-385 11846607