Analysis of the sfaXII locus in the Escherichia coli meningitis isolate IHE3034 reveals two novel regulatory genes within the promoter-distal region of the main S fimbrial operon

Microbial Pathogenesis

Volumn 46, Issue 3, 2009, Pages 150-158

  Sjöström, Annika E ^a   Sondén, Berit ^a   Müller, Claudia ^a   Rydström, Anna ^a   Dobrindt, Ulrich ^b   Wai, Sun Nyunt ^a   Uhlin, Bernt Eric ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Fimbrial genes; NMEC; Regulation; sfaXII; sfaYII

Indexed keywords

FIMBRIA PROTEIN; GENE PRODUCT; HISTONE LIKE NUCLEOID STRUCTURING PROTEIN; PHOSPHODIESTERASE;

ARTICLE; BACTERIAL GENE; BACTERIAL MENINGITIS; BACTERIUM ISOLATE; BIOFILM; BIOGENESIS; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; IMMUNOFLUORESCENCE MICROSCOPY; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; REPORTER GENE; S FIMBRIAL ADHESIN GENE; UROPATHOGENIC ESCHERICHIA COLI; VIBRIO CHOLERAE;

AMINO ACID SEQUENCE; ARTIFICIAL GENE FUSION; BASE SEQUENCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FIMBRIAE, BACTERIAL; GENE DELETION; GENE EXPRESSION PROFILING; GENE ORDER; GENES, BACTERIAL; GENES, REGULATOR; GENES, REPORTER; HUMANS; MENINGITIS, ESCHERICHIA COLI; MOLECULAR SEQUENCE DATA; OPERON; PHOSPHORIC DIESTER HYDROLASES; VIBRIO CHOLERAE;

ESCHERICHIA COLI; VIBRIO CHOLERAE;

EID: 60649088055     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2008.12.001     Document Type: Article

References (56)

1. Smith J.L., Fratamico P.M., and Gunther N.W. Extraintestinal pathogenic Escherichia coli. Foodborne Pathog Dis 4 2 (2007) 134-163
2. Hacker J., Schmidt G., Hughes C., Knapp S., Marget M., and Goebel W. Cloning and characterization of genes involved in production of mannose-resistant, neuraminidase-susceptible (X) fimbriae from a uropathogenic O6:K15:H31 Escherichia coli strain. Infect Immun 47 2 (1985) 434-440
3. Morschhauser J., Hoschützky H., Jann K., and Hacker J. Functional analysis of the sialic acid-binding adhesin SfaS of pathogenic Escherichia coli by site-specific mutagenesis. Infect Immun 58 7 (1990) 2133-2138
4. Hacker J., Kestler H., Hoschütsky H., Jann K., Lottspeich F., and Korhonen T.K. Cloning and characterization of the S fimbrial adhesin II complex of an Escherichia coli O18:K1 meningitis isolate. Infect Immun 61 2 (1993) 544-550
5. Dobrindt U., Blum-Oehler G., Hartsch T., Gottschalk G., Ron E.Z., Fünfstück R., et al. S-Fimbria-encoding determinant sfa(I) is located on pathogenicity island III(536) of uropathogenic Escherichia coli strain 536. Infect Immun 69 7 (2001) 4248-4256
6. Vetter V. Analysis of the S-fimbriae-minor-subunit-proteins mediating adherence of pathogenic Escherichia coli (1995), Institut für Molekulare Infektionsbiologie, Bayerischen Julius-Maximilians-Universität, Würzburg 167 [PhD Dissertation]
7. Norgren M., Normark S., Lark D., O'Hanley P., Schoolnik G., Falkow S., et al. Mutations in E coli cistrons affecting adhesion to human cells do not abolish Pap pili fiber formation. EMBO J 3 5 (1984) 1159-1165
8. Lindberg F.P., Lund B., and Normark S. Genes of pyelonephritogenic E. coli required for digalactoside-specific agglutination of human cells. EMBO J 3 5 (1984) 1167-1173
9. Marklund B.I., Tennent J.M., Garcia E., Hamers A., Bȧga M., Lindberg F., et al. Horizontal gene transfer of the Escherichia coli pap and prs pili operons as a mechanism for the development of tissue-specific adhesive properties. Mol Microbiol 6 16 (1992) 2225-2242
10. Simm R., Morr M., Kader A., Nimtz M., and Römling U. GGDEF and EAL domains inversely regulate cyclic di-GMP levels and transition from sessility to motility. Mol Microbiol 53 4 (2004) 1123-1134
11. Ryjenkov D.A., Tarutina M., Moskvin O.V., and Gomelsky M. Cyclic diguanylate is a ubiquitous signaling molecule in bacteria: insights into biochemistry of the GGDEF protein domain. J Bacteriol 187 5 (2005) 1792-1798
12. Schmidt A.J., Ryjenkov D.A., and Gomelsky M. The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains. J Bacteriol 187 14 (2005) 4774-4781
13. Mendez-Ortiz M.M., Hyodo M., Hayakawa Y., and Membrillo-Hernández J. Genome-wide transcriptional profile of Escherichia coli in response to high levels of the second messenger 3′,5′-cyclic diguanylic acid. J Biol Chem 281 12 (2006) 8090-8099
14. Korhonen T.K., Valtonen M.V., Parkkinen J., Väisänen-Rhen V., Finne J., et al. Serotypes, hemolysin production, and receptor recognition of Escherichia coli strains associated with neonatal sepsis and meningitis. Infect Immun 48 2 (1985) 486-491
15. Pouttu R., Westerlund-Wikström B., Lång H., Alsti K., Virkola R., Saarela U., et al. matB, a common fimbrillin gene of Escherichia coli, expressed in a genetically conserved, virulent clonal group. J Bacteriol 183 16 (2001) 4727-4736
16. Selander R.K., Korhonen T.K., Väisänen-Rhen V., Williams P.H., Pattison P.E., and Caugant D.A. Genetic relationships and clonal structure of strains of Escherichia coli causing neonatal septicemia and meningitis. Infect Immun 52 1 (1986) 213-222
17. Atlung T., and Ingmer H. H-NS: a modulator of environmentally regulated gene expression. Mol Microbiol 24 1 (1997) 7-17
18. Muller C.M., Dobridt U., Nagy G., Emödy L., Uhlin B.E., and Hacker J. Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli. J Bacteriol 188 15 (2006) 5428-5438
19. Schmoll T., Ott M., Oudega B., and Hacker J. Use of a wild-type gene fusion to determine the influence of environmental conditions on expression of the S fimbrial adhesin in an Escherichia coli pathogen. J Bacteriol 172 9 (1990) 5103-5111
20. Baga M., Göransson M., Normark S., and Uhlin B.E. Transcriptional activation of a Pap pilus virulence operon from uropathogenic Escherichia coli. EMBO J 4 13B (1985) 3887-3893
21. Goransson M., Forsman K., and Uhlin B.E. Regulatory genes in the thermoregulation of Escherichia coli pili gene transcription. Genes Dev 3 1 (1989) 123-130
22. Morschhauser J., Vetter V., Emödy L., and Hacker J. Adhesin regulatory genes within large, unstable DNA regions of pathogenic Escherichia coli: cross-talk between different adhesin gene clusters. Mol Microbiol 11 3 (1994) 555-566
23. Forsman K., Goransson M., and Uhlin B.E. Autoregulation and multiple DNA interactions by a transcriptional regulatory protein in E. coli pili biogenesis. EMBO J 8 4 (1989) 1271-1277
24. Xia Y., and Uhlin B.E. Mutational analysis of the PapB transcriptional regulator in Escherichia coli. Regions important for DNA binding and oligomerization. J Biol Chem 274 28 (1999) 19723-19730
25. Balsalobre C., Morschhäuser J., Jass J., Hacker J., and Uhlin B.E. Transcriptional analysis of the sfa determinant revealing mRNA processing events in the biogenesis of S fimbriae in pathogenic Escherichia coli. J Bacteriol 185 2 (2003) 620-629
26. Dobrindt U., Agerer F., Michaelis K., Janka A., Buchrieser C., Samuelson M., et al. Analysis of genome plasticity in pathogenic and commensal Escherichia coli isolates by use of DNA arrays. J Bacteriol 185 6 (2003) 1831-1840
27. Carniel E., Guilvout I., and Prentice M. Characterization of a large chromosomal "high-pathogenicity island" in biotype 1B Yersinia enterocolitica. J Bacteriol 178 23 (1996) 6743-6751
28. Bach S., de Almeida A., and Carniel E. The Yersinia high-pathogenicity island is present in different members of the family Enterobacteriaceae. FEMS Microbiol Lett 183 2 (2000) 289-294
29. II protein from newborn meningitis E. coli is involved in regulation of motility and type 1 fimbriae expression, Microb. Pathog, submitted for publication.
30. Simms A.N., and Mobley H.L. PapX, a P fimbrial operon-encoded inhibitor of motility in uropathogenic Escherichia coli. Infect Immun 76 11 (2008) 4833-4841
31. Waters C.M., Lu W., Rabinowitz J.D., and Bassler B.L. Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. J Bacteriol 190 7 (2008) 2527-2536
32. Vance R.E., Zhu J., and Mekalanos J.J. A constitutively active variant of the quorum-sensing regulator LuxO affects protease production and biofilm formation in Vibrio cholerae. Infect Immun 71 5 (2003) 2571-2576
33. Wai S.N., Mizunoe Y., Takade A., Kawabata S.I., and Yoshida S.I. Vibrio cholerae O1 strain TSI-4 produces the exopolysaccharide materials that determine colony morphology, stress resistance, and biofilm formation. Appl Environ Microbiol 64 10 (1998) 3648-3655
34. Sambrook J., and Russel D.W. Molecular cloning: a laboratory manual. 3rd ed (2001), Cold Spring Harbor Laboratory Press,, Cold Spring Harbor, NY
35. Link A.J., Phillips D., and Church G.M. Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization. J Bacteriol 179 20 (1997) 6228-6237
36. Willetts N.S., Clark A.J., and Low B. Genetic location of certain mutations conferring recombination deficiency in Escherichia coli. J Bacteriol 97 1 (1969) 244-249
37. Murphy K.C., and Campellone K.G. Lambda Red-mediated recombinogenic engineering of enterohemorrhagic and enteropathogenic E. coli. BMC Mol Biol 4 1 (2003) 11
38. Datsenko K.A., and Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A 97 12 (2000) 6640-6645
39. Miller J.H. A short course in bacterial genetics (1992), Cold Spring Harbor Laboratory Press,, Cold Spring Harbor, NY
40. Henning U., Schwarz H., and Chen R. Radioimmunological screening method for specific membrane proteins. Anal Biochem 97 1 (1979) 153-157
41. von Gabain A., Belasco J.G., Schottel J.L., Chang A.C., and Cohen S.N. Decay of mRNA in Escherichia coli: investigation of the fate of specific segments of transcripts. Proc Natl Acad Sci U S A 80 3 (1983) 653-657
42. Boyer H.W., and Roulland-Dussoix D. A complementation analysis of the restriction and modification of DNA in Escherichia coli. J Mol Biol 41 3 (1969) 459-472
43. Guyer M.S., Reed R.R., Steitz J.A., and Low K.B. Identification of a sex-factor-affinity site in E. coli as gamma delta. Cold Spring Harb Symp Quant Biol 45 Pt 1 (1981) 135-140
44. Aberg A., Shingler V., and Balsalobre C. Regulation of the fimB promoter: a case of differential regulation by ppGpp and DksA in vivo. Mol Microbiol 67 6 (2008) 1223-1241
45. Blomfield I.C., Calie P.J., Eberhardt K.J., McClain M.S., and Eisenstein B.I. Lrp stimulates phase variation of type 1 fimbriation in Escherichia coli K-12. J Bacteriol 175 1 (1993) 27-36
46. Johansson J., and Uhlin B.E. Differential protease-mediated turnover of H-NS and StpA revealed by a mutation altering protein stability and stationary-phase survival of Escherichia coli. Proc Natl Acad Sci U S A 96 19 (1999) 10776-10781
47. Thelin K.H., and Taylor R.K. Toxin-coregulated pilus, but not mannose-sensitive hemagglutinin, is required for colonization by Vibrio cholerae O1 El Tor biotype and O139 strains. Infect Immun 64 7 (1996) 2853-2856
48. Yanisch-Perron C., Vieira J., and Messing J. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33 1 (1985) 103-119
49. Bolivar F., Rodriguez R.L., Greene P.J., Betlach M.C., Heyneker H.L., and Boyer H.W. Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene 2 2 (1977) 95-113
50. Furste J.P., Pansegrau W., Frank R., Blöcker H., Scholz P., Bagdasarian M., et al. Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene 48 1 (1986) 119-131
51. Guzman L.M., Belin D., Carson M.J., and Beckwith J. Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J Bacteriol 177 14 (1995) 4121-4130
52. Brosius J. Superpolylinkers in cloning and expression vectors. DNA 8 10 (1989) 759-777
53. Kalogeraki V.S., and Winans S.C. Suicide plasmids containing promoterless reporter genes can simultaneously disrupt and create fusions to target genes of diverse bacteria. Gene 188 1 (1997) 69-75
54. Forsberg A.J., Pavitt G.D., and Higgins C.F. Use of transcriptional fusions to monitor gene expression: a cautionary tale. J Bacteriol 176 7 (1994) 2128-2132
55. Posfai G., Koob M.D., Kirkpatrick H.A., and Blattner F.R. Versatile insertion plasmids for targeted genome manipulations in bacteria: isolation, deletion, and rescue of the pathogenicity island LEE of the Escherichia coli O157:H7 genome. J Bacteriol 179 13 (1997) 4426-4428
56. Xia Y., Gally D., Forsman-Semb K., and Uhlin B.E. Regulatory cross-talk between adhesin operons in Escherichia coli: inhibition of type 1 fimbriae expression by the PapB protein. EMBO J 19 7 (2000) 1450-1457