The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 7, 2009, Pages 2313-2318

  Gruhne, Bettina ^a   Sompallae, Ramakrishna ^a   Marescotti, Diego ^a,b   Kamranvar, Siamak Akbari ^a   Gastaldello, Stefano ^a,c   Masucci, Maria G ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

DNA damage; EBNA 1; EBV; ROS

Indexed keywords

EPSTEIN BARR VIRUS ANTIGEN; EPSTEIN BARR VIRUS ANTIGEN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; GENE INDUCTION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; LEUKOCYTE; PRIORITY JOURNAL; RNA INTERFERENCE; TRANSCRIPTION INITIATION;

ANTIGENS, VIRAL; ANTIOXIDANTS; CATALYTIC DOMAIN; CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; DNA DAMAGE; EPSTEIN-BARR VIRUS NUCLEAR ANTIGENS; GENOMIC INSTABILITY; HUMANS; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; NADP; NADPH OXIDASE; NEOPLASMS; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL ACTIVATION;

HUMAN HERPESVIRUS 4;

EID: 60549111976     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0810619106     Document Type: Article

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