메뉴 건너뛰기




Volumn 72, Issue 6, 2009, Pages 410-427

Two-generation reproductive toxicity study of implanted depleted uranium (DU) in CD rats

Author keywords

[No Author keywords available]

Indexed keywords

URANIUM;

EID: 60549105381     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390802647344     Document Type: Article
Times cited : (15)

References (71)
  • 2
    • 0035384490 scopus 로고    scopus 로고
    • A review of the effects of uranium and depleted uranium exposure on reproduction and fetal development
    • Arfsten, D. P., Still, K. R., and Ritchie, G. D. 2001. A review of the effects of uranium and depleted uranium exposure on reproduction and fetal development. Toxicol. Ind. Health 17:180-191.
    • (2001) Toxicol. Ind. Health , vol.17 , pp. 180-191
    • Arfsten, D.P.1    Still, K.R.2    Ritchie, G.D.3
  • 4
    • 31544465707 scopus 로고    scopus 로고
    • Evaluation of the effect of implanted depleted uranium on male reproductive success, sperm concentration, and sperm velocity
    • Arfsten, D. P., Schaeffer, D. J., Johnson, E. W., Cunningham, J. R., Still, K. R., and Wilfong, E. R. 2006. Evaluation of the effect of implanted depleted uranium on male reproductive success, sperm concentration, and sperm velocity. Environ. Res. 100:205-215.
    • (2006) Environ. Res , vol.100 , pp. 205-215
    • Arfsten, D.P.1    Schaeffer, D.J.2    Johnson, E.W.3    Cunningham, J.R.4    Still, K.R.5    Wilfong, E.R.6
  • 6
    • 61649120253 scopus 로고    scopus 로고
    • BBC News. 2004. Gulf soldier wins pension fight. February 2.
    • BBC News. 2004. Gulf soldier wins pension fight. February 2.
  • 7
    • 0031747919 scopus 로고    scopus 로고
    • Long-term changes in rat social behavior following treatment with trimethylolpropane
    • Bekkedal, M. Y., Panksepp, J., and Rossi, J. III. 1998. Long-term changes in rat social behavior following treatment with trimethylolpropane. Neurotoxicol. Teratol. 20:307-316.
    • (1998) Neurotoxicol. Teratol , vol.20 , pp. 307-316
    • Bekkedal, M.Y.1    Panksepp, J.2    Rossi III, J.3
  • 8
    • 0033059031 scopus 로고    scopus 로고
    • Fetal and neonatal exposure to trimethylolpropane phosphate alters rat social behavior and emotional responsivity
    • Bekkedal, M. Y., Rossi, J. III, and Panksepp, J. 1999. Fetal and neonatal exposure to trimethylolpropane phosphate alters rat social behavior and emotional responsivity. Neurotoxicol. Teratol. 21:435-443.
    • (1999) Neurotoxicol. Teratol , vol.21 , pp. 435-443
    • Bekkedal, M.Y.1    Rossi III, J.2    Panksepp, J.3
  • 10
    • 0012566148 scopus 로고    scopus 로고
    • Evaluation of the health risks of embedded depleted uranium (DU) shrapnel on pregnancy and offspring development
    • Annual Report 19981118 065. Ft. Detrick, MD: U. S. Army Medical Research and Material Command, October
    • Benson, K. A. 1998. Evaluation of the health risks of embedded depleted uranium (DU) shrapnel on pregnancy and offspring development. Annual Report 19981118 065. Ft. Detrick, MD: U. S. Army Medical Research and Material Command, October.
    • (1998)
    • Benson, K.A.1
  • 11
    • 0000426772 scopus 로고    scopus 로고
    • Uranium levels in the fetus and placenta of female rats implanted with depleted uranium pellets prior to breeding
    • Benson, K. A., and McBride, S. A. 1997. Uranium levels in the fetus and placenta of female rats implanted with depleted uranium pellets prior to breeding. Toxicologist 36:258.
    • (1997) Toxicologist , vol.36 , pp. 258
    • Benson, K.A.1    McBride, S.A.2
  • 12
    • 0027064619 scopus 로고
    • Embryotoxicity of uranium in mice. Variability with the day of exposure
    • Bosque, M. A., Domingo, J. L., and Corbella, J. 1992. Embryotoxicity of uranium in mice. Variability with the day of exposure. Rev. Toxicol. 9:107-110.
    • (1992) Rev. Toxicol , vol.9 , pp. 107-110
    • Bosque, M.A.1    Domingo, J.L.2    Corbella, J.3
  • 13
    • 0027537235 scopus 로고
    • Embryotoxicity and teratogenicity of uranium in mice following SC administration of uranyl acetate
    • Bosque, M. A., Domingo, J. L., Llobet, J. M., and Corbella, J. 1993. Embryotoxicity and teratogenicity of uranium in mice following SC administration of uranyl acetate. Biol. Trace Elem. Res. 36:109-118.
    • (1993) Biol. Trace Elem. Res , vol.36 , pp. 109-118
    • Bosque, M.A.1    Domingo, J.L.2    Llobet, J.M.3    Corbella, J.4
  • 14
    • 12844283105 scopus 로고    scopus 로고
    • Altered open-field performance in depleted uranium exposed rats
    • Briner, W. 2002. Altered open-field performance in depleted uranium exposed rats. Metal Ions Biol. Med. 7:342-345.
    • (2002) Metal Ions Biol. Med , vol.7 , pp. 342-345
    • Briner, W.1
  • 15
    • 12844256180 scopus 로고    scopus 로고
    • Lipid oxidation and behavior are correlated in depleted uranium exposed mice
    • Briner, W., and Davis, D. 2002. Lipid oxidation and behavior are correlated in depleted uranium exposed mice. Metal Ions Biol. Med. 7:59-63.
    • (2002) Metal Ions Biol. Med , vol.7 , pp. 59-63
    • Briner, W.1    Davis, D.2
  • 16
    • 12844273624 scopus 로고    scopus 로고
    • Effects of short-term and long-term depleted uranium exposure on open-field behavior and brain lipid oxidation in rats
    • Briner, W., and Murray, J. 2005. Effects of short-term and long-term depleted uranium exposure on open-field behavior and brain lipid oxidation in rats. Neurotoxicol. Teratol. 27:135-144.
    • (2005) Neurotoxicol. Teratol , vol.27 , pp. 135-144
    • Briner, W.1    Murray, J.2
  • 17
    • 61649092700 scopus 로고    scopus 로고
    • Centre for Health Promotion and Preventative Medicine. 2000. Depleted uranium - Human exposure assessment and health risk characterization in support of the environmental exposure report Depleted Uranium in the Gulf of the Office of the Special Assistant to the Secretary of Defense for Gulf War Illnesses, Medical Readiness and Military Deployments (OSAGWI). Aberdeen Proving Ground, MD: Health Risk Consultation 26-MF-7555-00D. Army Centre for Health Promotion and Preventative Medicine, September.
    • Centre for Health Promotion and Preventative Medicine. 2000. Depleted uranium - Human exposure assessment and health risk characterization in support of the environmental exposure report "Depleted Uranium in the Gulf" of the Office of the Special Assistant to the Secretary of Defense for Gulf War Illnesses, Medical Readiness and Military Deployments (OSAGWI). Aberdeen Proving Ground, MD: Health Risk Consultation 26-MF-7555-00D. Army Centre for Health Promotion and Preventative Medicine, September.
  • 18
    • 84944661914 scopus 로고
    • Rank transformations as a bridge between parametric and nonparametric statistics
    • Conover, W. J., and Iman, R. L. 1981. Rank transformations as a bridge between parametric and nonparametric statistics. Am. Stat. 35:124-133.
    • (1981) Am. Stat , vol.35 , pp. 124-133
    • Conover, W.J.1    Iman, R.L.2
  • 20
    • 0035658190 scopus 로고    scopus 로고
    • Reproductive and developmental toxicity of natural and depleted uranium: A review
    • Domingo, J. L. 2001. Reproductive and developmental toxicity of natural and depleted uranium: A review. Reprod. Toxicol. 15:603-609.
    • (2001) Reprod. Toxicol , vol.15 , pp. 603-609
    • Domingo, J.L.1
  • 24
    • 33748615712 scopus 로고    scopus 로고
    • Brain accumulation of depleted uranium in rats following 3- or 6-month treatment with implanted depleted uranium pellets
    • Fitsanakis, V. A., Erikson, K. M., Garcia, S. J., Evje, L., Syversen, T., and Aschner, M. 2006. Brain accumulation of depleted uranium in rats following 3- or 6-month treatment with implanted depleted uranium pellets. Biol. Trace Elem. Res. 111:185-197.
    • (2006) Biol. Trace Elem. Res , vol.111 , pp. 185-197
    • Fitsanakis, V.A.1    Erikson, K.M.2    Garcia, S.J.3    Evje, L.4    Syversen, T.5    Aschner, M.6
  • 25
    • 61649085777 scopus 로고    scopus 로고
    • Gulf veteran babies 'risk deformities'
    • August 11. Available at
    • Fleming, N., and Townsend, M. 2002. Gulf veteran babies 'risk deformities'. The Observer, August 11. Available at http://www.guardian. co.uk/policitics/2002/avg/11/uk.politicalnews.
    • (2002) The Observer
    • Fleming, N.1    Townsend, M.2
  • 26
    • 84872269687 scopus 로고    scopus 로고
    • Uran-geschosse:Schwergeschaedigte Soldaten, missgebildete Neugeborene, sterbende Kinder [Uranium projectiles severely maimed soldiers, deformed babies, dying children]
    • AHRIMAN-Verlag GmbH, Freiburg, Germany
    • Gunther, S. H. 2000. Uran-geschosse:Schwergeschaedigte Soldaten, missgebildete Neugeborene, sterbende Kinder [Uranium projectiles severely maimed soldiers, deformed babies, dying children]. Projectiles d'uranium: Militaires gravement mutiles, nouveau-nes defformes, enfants mourants AHRIMAN-Verlag GmbH, Freiburg, Germany.
    • (2000) Projectiles d'uranium: Militaires gravement mutiles, nouveau-nes defformes, enfants mourants
    • Gunther, S.H.1
  • 27
    • 0036151107 scopus 로고    scopus 로고
    • Implanted depleted uranium fragments cause soft tissue sarcomas in the muscles of rats
    • Hahn, F. F., Guilmette, R. A., and Hoover, M. D. 2002. Implanted depleted uranium fragments cause soft tissue sarcomas in the muscles of rats. Environ. Health Perspect. 110:51-59.
    • (2002) Environ. Health Perspect , vol.110 , pp. 51-59
    • Hahn, F.F.1    Guilmette, R.A.2    Hoover, M.D.3
  • 28
    • 13644256065 scopus 로고    scopus 로고
    • A review of the methods of studies on infant ultrasound production and maternal retrieval in small rodents
    • Hahn, M. E., and Lavooy, M. J. 2005. A review of the methods of studies on infant ultrasound production and maternal retrieval in small rodents. Behav. Genet. 35:31-52.
    • (2005) Behav. Genet , vol.35 , pp. 31-52
    • Hahn, M.E.1    Lavooy, M.J.2
  • 30
    • 26444606400 scopus 로고    scopus 로고
    • Teratogenicity of depleted uranium aerosols: A review from an epidemiological perspective
    • Hindin, R., Brugge, D., and Panikkar, B. 2005. Teratogenicity of depleted uranium aerosols: A review from an epidemiological perspective. Environ. Health 4:17.
    • (2005) Environ. Health , vol.4 , pp. 17
    • Hindin, R.1    Brugge, D.2    Panikkar, B.3
  • 31
    • 0024422982 scopus 로고
    • Isolation distress and maternal comfort responses of two-week-old rat pups reared in social isolation
    • Hofer, M. A., Shair, H. N., and Murowchick, E. 1989. Isolation distress and maternal comfort responses of two-week-old rat pups reared in social isolation. Dev. Psychobiol. 22:553-566.
    • (1989) Dev. Psychobiol , vol.22 , pp. 553-566
    • Hofer, M.A.1    Shair, H.N.2    Murowchick, E.3
  • 32
    • 27944474827 scopus 로고    scopus 로고
    • Enriched but not depleted uranium affects central nervous system in long-term exposed rat
    • Houpert, P., Lestaevel, P., Bussy, C., Paquet, F., and Gourmelon, P. 2005. Enriched but not depleted uranium affects central nervous system in long-term exposed rat. Neurotoxicology 26:1015-1020.
    • (2005) Neurotoxicology , vol.26 , pp. 1015-1020
    • Houpert, P.1    Lestaevel, P.2    Bussy, C.3    Paquet, F.4    Gourmelon, P.5
  • 33
    • 0002164651 scopus 로고
    • The tiny victims of Desert Storm
    • Hudson, D., and Miller, K. 1995. The tiny victims of Desert Storm. Life Magazine 18:46-59.
    • (1995) Life Magazine , vol.18 , pp. 46-59
    • Hudson, D.1    Miller, K.2
  • 34
    • 61649107991 scopus 로고    scopus 로고
    • ICBUW, International Coalition to Ban Uranium Weapons. 22 November
    • ICBUW. 2006. European parliament makes fourth call for DU ban. International Coalition to Ban Uranium Weapons. 22 November 2006. http://www.bandepleteduranium.org/en/a/89.html
    • (2006) European parliament makes fourth call for DU ban
  • 35
    • 0029416888 scopus 로고
    • Strain as a determinant factor in the differential responsiveness of rats to chemicals
    • Kacew, S., Ruben, Z., and McConnell, R. F. 1995. Strain as a determinant factor in the differential responsiveness of rats to chemicals. Toxicol. Pathol. 23:701-714.
    • (1995) Toxicol. Pathol , vol.23 , pp. 701-714
    • Kacew, S.1    Ruben, Z.2    McConnell, R.F.3
  • 37
    • 0034847857 scopus 로고    scopus 로고
    • Pregnancy outcomes among U.S. Gulf War veterans: A population-based survey of 30,000 veterans
    • Kang, H., Magee, C., Mahan, C., Lee, K., Murphy, F., Jackson, L., and Matanoski, G. 2001. Pregnancy outcomes among U.S. Gulf War veterans: A population-based survey of 30,000 veterans. Ann. Epidemiol. 11:504-511.
    • (2001) Ann. Epidemiol , vol.11 , pp. 504-511
    • Kang, H.1    Magee, C.2    Mahan, C.3    Lee, K.4    Murphy, F.5    Jackson, L.6    Matanoski, G.7
  • 39
    • 77957188007 scopus 로고
    • Influence of chronic exposure to uranium on male reproduction in mice
    • Llobet, J. M., Sirvent, J.J., Ortega, A., and Domingo, J. L. 1991. Influence of chronic exposure to uranium on male reproduction in mice. Fundam. Appl. Toxicol. 16:821-829.
    • (1991) Fundam. Appl. Toxicol , vol.16 , pp. 821-829
    • Llobet, J.M.1    Sirvent, J.J.2    Ortega, A.3    Domingo, J.L.4
  • 40
    • 0018255057 scopus 로고
    • Effect of uranium on the induction and course of experimental autoimmune orchitis and thyroiditis
    • Malenchenko, A. F., Barkun, N. A., and Guseva, G. F. 1978. Effect of uranium on the induction and course of experimental autoimmune orchitis and thyroiditis. J. Hyg. Epidemiol. Microbiol. Immunol. 22:268-277.
    • (1978) J. Hyg. Epidemiol. Microbiol. Immunol , vol.22 , pp. 268-277
    • Malenchenko, A.F.1    Barkun, N.A.2    Guseva, G.F.3
  • 41
    • 0001423037 scopus 로고
    • Oral toxicity of uranium compounds
    • eds. C. Voegtlin and H.C. Hodge, pp, New York: McGraw-Hill
    • Maynard, E. A., Downs, W. L., and Hodge, H. C. 1953. Oral toxicity of uranium compounds. In Pharmacology and toxicology of uranium, vol. III, eds. C. Voegtlin and H.C. Hodge, pp. 1221-1369. New York: McGraw-Hill.
    • (1953) Pharmacology and toxicology of uranium , vol.3 , pp. 1221-1369
    • Maynard, E.A.1    Downs, W.L.2    Hodge, H.C.3
  • 47
    • 23644448595 scopus 로고    scopus 로고
    • Effects of depleted uranium on survival, growth, and metamorphosis in the African clawed frog (Xenopus laevis)
    • Mitchell, S. E., Caldwell, C. A., Gonzales, G., Gould, W. R., and Arimoto, R. 2005. Effects of depleted uranium on survival, growth, and metamorphosis in the African clawed frog (Xenopus laevis). J. Toxicol. Environ. Health A 68:951-965.
    • (2005) J. Toxicol. Environ. Health A , vol.68 , pp. 951-965
    • Mitchell, S.E.1    Caldwell, C.A.2    Gonzales, G.3    Gould, W.R.4    Arimoto, R.5
  • 50
    • 24944552856 scopus 로고    scopus 로고
    • Bioaccumulation and behavioural effects of depleted uranium in rats exposed to repeated inhalations
    • Monleau, M., Bussy, C., Lestaevel, P., Houpert, P., Paquet, F., and Chazel, V. 2005. Bioaccumulation and behavioural effects of depleted uranium in rats exposed to repeated inhalations. Neurosci. Lett. 390:31-36.
    • (2005) Neurosci. Lett , vol.390 , pp. 31-36
    • Monleau, M.1    Bussy, C.2    Lestaevel, P.3    Houpert, P.4    Paquet, F.5    Chazel, V.6
  • 51
    • 0003913207 scopus 로고    scopus 로고
    • Guidance document on the recognition, assessment, and use of clinical signs as humane endpoints for experimental animals used in safety evaluation
    • Organization for Economic Cooperation and Development, Organization of Economic Cooperation and Development OECD, Paris:Environment Directorate, Organization for Economic Co-Operation and Development
    • Organization for Economic Cooperation and Development. 2000. Guidance document on the recognition, assessment, and use of clinical signs as humane endpoints for experimental animals used in safety evaluation. Organization of Economic Cooperation and Development (OECD) Environmental Health and Safety Publications Series on Testing and Assessment. No. 19. Paris:Environment Directorate, Organization for Economic Co-Operation and Development.
    • (2000) Environmental Health and Safety Publications Series on Testing and Assessment , vol.19
  • 52
    • 0021672689 scopus 로고
    • The psychobiology of play: Theoretical and methodological perspectives
    • Panksepp, J., Siviy, S., and Normansell, L. 1984. The psychobiology of play: Theoretical and methodological perspectives. Neurosci. Biobehav. Rev. 8:465-492.
    • (1984) Neurosci. Biobehav. Rev , vol.8 , pp. 465-492
    • Panksepp, J.1    Siviy, S.2    Normansell, L.3
  • 53
    • 0024338972 scopus 로고
    • The effects of uranium on reproduction, gestation, and postnatal survival in mice
    • Paternain, J. L., Domingo, J. L., Ortega, A., and Llobet, J. M. 1989. The effects of uranium on reproduction, gestation, and postnatal survival in mice. Ecotoxicol. Environ. Safety 17:291-296.
    • (1989) Ecotoxicol. Environ. Safety , vol.17 , pp. 291-296
    • Paternain, J.L.1    Domingo, J.L.2    Ortega, A.3    Llobet, J.M.4
  • 54
    • 35748933380 scopus 로고    scopus 로고
    • Health risk assessment of embedded depleted uranium: Behavior, physiology, histology, and biokinetic modeling
    • Fort Detrick, MD:U.S. Army Medical Research and Material Command
    • Pellmar, T. C. 1996. Health risk assessment of embedded depleted uranium: Behavior, physiology, histology, and biokinetic modeling. AD Number: ADB227638. Fort Detrick, MD:U.S. Army Medical Research and Material Command.
    • (1996) AD Number: ADB227638
    • Pellmar, T.C.1
  • 58
    • 0012566151 scopus 로고    scopus 로고
    • Toxic byproduct of fighting in Kosovo
    • January 14. Available at
    • Schoettler, C. 2001. Toxic byproduct of fighting in Kosovo. Baltimore Sun, January 14. Available at http://www.geocities.com/hebdo99/dossier/ BERRIGAN.htm?200911.
    • (2001) Baltimore Sun
    • Schoettler, C.1
  • 60
    • 31544483115 scopus 로고
    • Method of euthanasia does not affect sperm motility in the laboratory rat
    • Slott, V. L., Linder, R. E., and Dyer, C. J. 1994. Method of euthanasia does not affect sperm motility in the laboratory rat. Reprod. Toxicol. 12:105-114.
    • (1994) Reprod. Toxicol , vol.12 , pp. 105-114
    • Slott, V.L.1    Linder, R.E.2    Dyer, C.J.3
  • 61
    • 23844467418 scopus 로고    scopus 로고
    • Prediction of renal concentrations of depleted uranium and radiation dose in Gulf War veterans with embedded shrapnel
    • Squibb, K. S., Leggett, R. W., and McDiarmid, M. A. 2005. Prediction of renal concentrations of depleted uranium and radiation dose in Gulf War veterans with embedded shrapnel. Health Phys. 89:267-273.
    • (2005) Health Phys , vol.89 , pp. 267-273
    • Squibb, K.S.1    Leggett, R.W.2    McDiarmid, M.A.3
  • 62
    • 0030293842 scopus 로고    scopus 로고
    • Comparison of rat epididymal sperm counts by IVOS HTM-IDENT and hemacytometer
    • Strader, L. F., Linder, R. E., and Perreault, S. D. 1996. Comparison of rat epididymal sperm counts by IVOS HTM-IDENT and hemacytometer. Reprod. Toxicol. 10:529-533.
    • (1996) Reprod. Toxicol , vol.10 , pp. 529-533
    • Strader, L.F.1    Linder, R.E.2    Perreault, S.D.3
  • 63
    • 1542723559 scopus 로고    scopus 로고
    • Chemical and radiological toxicity of depleted uranium
    • Sztajnkrycer, M. D., and Otten, E. J. 2004. Chemical and radiological toxicity of depleted uranium. Mil. Med. 169:212-216.
    • (2004) Mil. Med , vol.169 , pp. 212-216
    • Sztajnkrycer, M.D.1    Otten, E.J.2
  • 64
    • 27644572227 scopus 로고    scopus 로고
    • Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on murine heart development: Alteration in fetal and postnatal cardiac growth, and postnatal cardiac chronotropy
    • Thackaberry, E. A., Nunez, B. A., Ivnitski-Steele, I. D., Friggins, M., and Walker, M. K. 2005. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on murine heart development: Alteration in fetal and postnatal cardiac growth, and postnatal cardiac chronotropy. Toxicol. Sci. 88:242-249.
    • (2005) Toxicol. Sci , vol.88 , pp. 242-249
    • Thackaberry, E.A.1    Nunez, B.A.2    Ivnitski-Steele, I.D.3    Friggins, M.4    Walker, M.K.5
  • 67
    • 38349052278 scopus 로고    scopus 로고
    • Depleted uranium, state crime and the politics of knowing
    • White, R. 2008. Depleted uranium, state crime and the politics of knowing. Theoret. Criminol. 12:31-54.
    • (2008) Theoret. Criminol , vol.12 , pp. 31-54
    • White, R.1
  • 68
    • 0029294090 scopus 로고
    • Isolation of rat sperm from the vas deferens for sperm motion analysis
    • Wier, P. J., and Rumberger, D. 1995. Isolation of rat sperm from the vas deferens for sperm motion analysis. Reprod. Toxicol. 9:327-330.
    • (1995) Reprod. Toxicol , vol.9 , pp. 327-330
    • Wier, P.J.1    Rumberger, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.