메뉴 건너뛰기




Volumn 39, Issue 1, 2009, Pages 178-191

Photodynamic vaccination of hamsters with inducible suicidal mutants of Leishmania amazonensis elicits immunity against visceral leishmaniasis

Author keywords

Porphyrinogenic mutant; Suicidal vaccination; T cell adoptive transfer; Visceral leishmaniasis

Indexed keywords

AMINOLEVULINIC ACID; GAMMA INTERFERON; IMMUNOGLOBULIN G2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; LEISHMANIA VACCINE; CYTOKINE; PHOTOSENSITIZING AGENT; PORPHYRINOGEN; PROTOZOON ANTIBODY;

EID: 60549098684     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838389     Document Type: Article
Times cited : (39)

References (58)
  • 1
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: Current situation and new perspectives
    • Desjeux, P., Leishmaniasis: Current situation and new perspectives. Comp. Immunol. Microbiol. Infect. Dis. 2004. 27: 305-318.
    • (2004) Comp. Immunol. Microbiol. Infect. Dis , vol.27 , pp. 305-318
    • Desjeux, P.1
  • 3
    • 0035067363 scopus 로고    scopus 로고
    • Leishmaniasis: Current status of vaccine development
    • Handman, E., Leishmaniasis: Current status of vaccine development. Clin. Microbiol. Rev. 2001. 14: 229-243.
    • (2001) Clin. Microbiol. Rev , vol.14 , pp. 229-243
    • Handman, E.1
  • 4
    • 0034780949 scopus 로고    scopus 로고
    • Drug resistance in Indian visceral leishmaniasis
    • Sundar, S., Drug resistance in Indian visceral leishmaniasis. Trop. Med. Int. Health 2001. 6: 849-854.
    • (2001) Trop. Med. Int. Health , vol.6 , pp. 849-854
    • Sundar, S.1
  • 5
    • 0027172259 scopus 로고
    • T-cell and cytokine responses in leishmaniasis
    • Reed, S. G. and Scott, P., T-cell and cytokine responses in leishmaniasis. Curr. Opin. Immunol. 1993. 5: 524-531.
    • (1993) Curr. Opin. Immunol , vol.5 , pp. 524-531
    • Reed, S.G.1    Scott, P.2
  • 6
    • 0031948654 scopus 로고    scopus 로고
    • Cloning of Syrian hamster (Mesocricetus auratus) cytokine cDNAs and analysis of cytokine mRNA expression in experimental visceral leishmaniasis
    • Melby, P. C., Tryon, V. V., Chandrasekar, B. and Freeman, G. L., Cloning of Syrian hamster (Mesocricetus auratus) cytokine cDNAs and analysis of cytokine mRNA expression in experimental visceral leishmaniasis. Infect. Immun. 1998. 66: 2135-2142.
    • (1998) Infect. Immun , vol.66 , pp. 2135-2142
    • Melby, P.C.1    Tryon, V.V.2    Chandrasekar, B.3    Freeman, G.L.4
  • 7
    • 33745199610 scopus 로고    scopus 로고
    • Animal models for vaccine studies for visceral leishmaniasis
    • Garg, R. and Dube, A., Animal models for vaccine studies for visceral leishmaniasis. Indian J. Med. Res. 2006. 123: 439-454.
    • (2006) Indian J. Med. Res , vol.123 , pp. 439-454
    • Garg, R.1    Dube, A.2
  • 8
    • 0019251264 scopus 로고
    • The present and future of vaccination for cutaneous leishmaniasis
    • Greenblatt, C. L., The present and future of vaccination for cutaneous leishmaniasis. Prog. Clin. Biol. Res. 1980. 47: 259-285.
    • (1980) Prog. Clin. Biol. Res , vol.47 , pp. 259-285
    • Greenblatt, C.L.1
  • 9
    • 25444511090 scopus 로고    scopus 로고
    • Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis
    • Breton, M., Tremblay, M. J., Ouellette, M. and Papadopoulou, B., Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis. Infect. Immun. 2005. 73: 6372-6382.
    • (2005) Infect. Immun , vol.73 , pp. 6372-6382
    • Breton, M.1    Tremblay, M.J.2    Ouellette, M.3    Papadopoulou, B.4
  • 10
    • 61449223415 scopus 로고    scopus 로고
    • Coming Back: WHO/TDR initiative to support live attenuated vaccines
    • WHO/TDR, September
    • WHO/TDR, Coming Back: WHO/TDR initiative to support live attenuated vaccines. TDR News September 2005. No. 75.
    • (2005) TDR News , Issue.75
  • 11
    • 0030024793 scopus 로고    scopus 로고
    • Towards a strategy of universally efficacious vaccination against pathogens uniquely susceptible to cell-mediated attack
    • Bretscher, P. A., Menon, J. N. and Ogunremi, O., Towards a strategy of universally efficacious vaccination against pathogens uniquely susceptible to cell-mediated attack. J. Biotechnol. 1996. 44: 1-4.
    • (1996) J. Biotechnol , vol.44 , pp. 1-4
    • Bretscher, P.A.1    Menon, J.N.2    Ogunremi, O.3
  • 12
    • 0038583505 scopus 로고    scopus 로고
    • Leishmania mexicana and Leishmania major: Attenuation of wild-type parasites and vaccination with the attenuated lines
    • Daneshvar, H., Coombs, G. H., Hagan, P. and Phillips, R. S., Leishmania mexicana and Leishmania major: Attenuation of wild-type parasites and vaccination with the attenuated lines. J. Infect. Dis. 2003. 187: 1662-1668.
    • (2003) J. Infect. Dis , vol.187 , pp. 1662-1668
    • Daneshvar, H.1    Coombs, G.H.2    Hagan, P.3    Phillips, R.S.4
  • 13
    • 0242286543 scopus 로고    scopus 로고
    • Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice
    • Dumas, C., Muyombwe, A., Roy, G., Matte, C., Ouellette, M., Olivier, M. and Papadopoulou, B., Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice. Infect. Immun. 2003. 71: 6499-6509.
    • (2003) Infect. Immun , vol.71 , pp. 6499-6509
    • Dumas, C.1    Muyombwe, A.2    Roy, G.3    Matte, C.4    Ouellette, M.5    Olivier, M.6    Papadopoulou, B.7
  • 14
    • 0031985934 scopus 로고    scopus 로고
    • Protection against Leishmania major challenge infection in mice vaccinated with live recombinant parasites expressing a cytotoxic gene
    • Muyombwe, A., Olivier, M., Harvie, P., Bergeron, M. G., Ouellette, M. and Papadopoulou, B., Protection against Leishmania major challenge infection in mice vaccinated with live recombinant parasites expressing a cytotoxic gene. J. Infect. Dis. 1998. 177: 188-195.
    • (1998) J. Infect. Dis , vol.177 , pp. 188-195
    • Muyombwe, A.1    Olivier, M.2    Harvie, P.3    Bergeron, M.G.4    Ouellette, M.5    Papadopoulou, B.6
  • 15
    • 0041322722 scopus 로고    scopus 로고
    • Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous leishmaniasis but maintains its potency and durability
    • Mendez, S., Tabbara, K., Belkaid, Y., Bertholet, S., Verthelyi, D., Klinman, D., Seder, R. A. and Sacks, D. L., Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous leishmaniasis but maintains its potency and durability. Infect. Immun. 2003. 71: 5121-5129.
    • (2003) Infect. Immun , vol.71 , pp. 5121-5129
    • Mendez, S.1    Tabbara, K.2    Belkaid, Y.3    Bertholet, S.4    Verthelyi, D.5    Klinman, D.6    Seder, R.A.7    Sacks, D.L.8
  • 16
    • 0037177902 scopus 로고    scopus 로고
    • Genetic rescue of Leishmania deficiency in porphyrin biosynthesis creates mutants suitable for analysis of cellular events in uroporphyria and for photodynamic therapy
    • Sah, J. F., Ito, H., Kolli, B. K., Peterson, D. A., Sassa, S. and Chang, K. P., Genetic rescue of Leishmania deficiency in porphyrin biosynthesis creates mutants suitable for analysis of cellular events in uroporphyria and for photodynamic therapy. J. Biol. Chem. 2002. 277: 14902-14909.
    • (2002) J. Biol. Chem , vol.277 , pp. 14902-14909
    • Sah, J.F.1    Ito, H.2    Kolli, B.K.3    Peterson, D.A.4    Sassa, S.5    Chang, K.P.6
  • 17
    • 0021075679 scopus 로고
    • Cell-mediated immune response in Indian kala-azar and post-kala-azar dermal leishmaniasis
    • Haldar, J. P., Ghose, S., Saha, K. C. and Ghose, A. C., Cell-mediated immune response in Indian kala-azar and post-kala-azar dermal leishmaniasis. Infect. Immun. 1983. 42: 702-707.
    • (1983) Infect. Immun , vol.42 , pp. 702-707
    • Haldar, J.P.1    Ghose, S.2    Saha, K.C.3    Ghose, A.C.4
  • 18
    • 0024442306 scopus 로고
    • Comparison of T-cell responses in self-limiting versus progressive visceral Leishmania donovani infections in golden hamsters
    • Gifawesen, C. and Farrell, J. P., Comparison of T-cell responses in self-limiting versus progressive visceral Leishmania donovani infections in golden hamsters. Infect. Immun. 1989. 57: 3091-3096.
    • (1989) Infect. Immun , vol.57 , pp. 3091-3096
    • Gifawesen, C.1    Farrell, J.P.2
  • 19
    • 33846847777 scopus 로고    scopus 로고
    • Leishmania vaccines: Progress and problems
    • Kedzierski, L., Zhu, Y. and Handman, E., Leishmania vaccines: Progress and problems. Parasitology 2006. 133: S87-S112.
    • (2006) Parasitology , vol.133
    • Kedzierski, L.1    Zhu, Y.2    Handman, E.3
  • 21
    • 0031883851 scopus 로고    scopus 로고
    • Detection of Leishmania (Viannia) braziliensis complex in wild mammals from Colombian coffee plantations by PCR and DNA hybridization
    • Alexander, B., Lozano, C., Barker, D. C., McCann, S. H., and Adler, G. H., Detection of Leishmania (Viannia) braziliensis complex in wild mammals from Colombian coffee plantations by PCR and DNA hybridization. Acta Trop. 1998. 69: 41-50.
    • (1998) Acta Trop , vol.69 , pp. 41-50
    • Alexander, B.1    Lozano, C.2    Barker, D.C.3    McCann, S.H.4    Adler, G.H.5
  • 22
    • 0036137174 scopus 로고    scopus 로고
    • Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination
    • Papadopoulou, B., Roy, G., Breton, M., Kundig, C., Dumas, C., Fillion, I., Singh, A. K. et al., Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination. Infect. Immun. 2002. 70: 62-68.
    • (2002) Infect. Immun , vol.70 , pp. 62-68
    • Papadopoulou, B.1    Roy, G.2    Breton, M.3    Kundig, C.4    Dumas, C.5    Fillion, I.6    Singh, A.K.7
  • 23
    • 0043180475 scopus 로고    scopus 로고
    • The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts
    • Spath, G. F., Garraway, L. A., Turco, S. J. and Beverley, S. M., The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts. Proc. Natl. Acad. Sci. USA 2003. 100: 9536-9541.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9536-9541
    • Spath, G.F.1    Garraway, L.A.2    Turco, S.J.3    Beverley, S.M.4
  • 24
    • 0042322609 scopus 로고    scopus 로고
    • Persistence without pathology in phosphoglycan-deficient Leishmania major
    • Spath, G. F., Lye, L. F., Segawa, H., Sacks, D. L., Turco, S. J. and Beverley, S. M., Persistence without pathology in phosphoglycan-deficient Leishmania major. Science 2003. 301: 1241-1243.
    • (2003) Science , vol.301 , pp. 1241-1243
    • Spath, G.F.1    Lye, L.F.2    Segawa, H.3    Sacks, D.L.4    Turco, S.J.5    Beverley, S.M.6
  • 25
    • 0036524670 scopus 로고    scopus 로고
    • The use of 5-aminolaevulinic acid as a photosensitiser in photodynamic therapy and photodiagnosis
    • Kelty, C. J., Brown, N. J., Reed, M. W. and Ackroyd, R., The use of 5-aminolaevulinic acid as a photosensitiser in photodynamic therapy and photodiagnosis. Photochem. Photobiol. Sci. 2002. 1: 158-168.
    • (2002) Photochem. Photobiol. Sci , vol.1 , pp. 158-168
    • Kelty, C.J.1    Brown, N.J.2    Reed, M.W.3    Ackroyd, R.4
  • 26
    • 23844437566 scopus 로고    scopus 로고
    • Killed but metabolically active microbes: A new vaccine paradigm for eliciting effector T-cell responses and protective immunity
    • Brockstedt, D. G., Bahjat, K. S., Giedlin, M. A., Liu, W., Leong, M., Luckett, W., Gao, Y. et al., Killed but metabolically active microbes: A new vaccine paradigm for eliciting effector T-cell responses and protective immunity. Nat. Med. 2005. 11: 853-860.
    • (2005) Nat. Med , vol.11 , pp. 853-860
    • Brockstedt, D.G.1    Bahjat, K.S.2    Giedlin, M.A.3    Liu, W.4    Leong, M.5    Luckett, W.6    Gao, Y.7
  • 27
    • 1542619246 scopus 로고    scopus 로고
    • Vaccination with phosphoglycan-deficient Leishmania major protects highly susceptible mice from virulent challenge without inducing a strong Th1 response
    • Uzonna, J. E., Spath, G. F., Beverley, S. M. and Scott, P., Vaccination with phosphoglycan-deficient Leishmania major protects highly susceptible mice from virulent challenge without inducing a strong Th1 response. J. Immunol. 2004. 172: 3793-3797.
    • (2004) J. Immunol , vol.172 , pp. 3793-3797
    • Uzonna, J.E.1    Spath, G.F.2    Beverley, S.M.3    Scott, P.4
  • 29
    • 27644473049 scopus 로고    scopus 로고
    • Photodynamic sensitization of Leishmania amazonensis in both extracellular and intracellular stages with aluminum phthalocyanine chloride for photolysis in vitro
    • Dutta, S., Ray, D., Kolli, B. K. and Chang, K. P., Photodynamic sensitization of Leishmania amazonensis in both extracellular and intracellular stages with aluminum phthalocyanine chloride for photolysis in vitro. Antimicrob. Agents Chemother. 2005. 49: 4474-4484.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 4474-4484
    • Dutta, S.1    Ray, D.2    Kolli, B.K.3    Chang, K.P.4
  • 30
    • 28044441564 scopus 로고    scopus 로고
    • Immunologic memory in cutaneous leishmaniasis
    • Scott, P., Immunologic memory in cutaneous leishmaniasis. Cell. Microbiol. 2005. 7: 1707-1713.
    • (2005) Cell. Microbiol , vol.7 , pp. 1707-1713
    • Scott, P.1
  • 31
    • 23344449993 scopus 로고    scopus 로고
    • Conditions influencing the efficacy of vaccination with live organisms against Leishmania major infection
    • Tabbara, K. S., Peters, N. C., Afrin, F., Mendez, S., Bertholet, S., Belkaid, Y. and Sacks, D. L., Conditions influencing the efficacy of vaccination with live organisms against Leishmania major infection. Infect. Immun. 2005. 73: 4714-4722.
    • (2005) Infect. Immun , vol.73 , pp. 4714-4722
    • Tabbara, K.S.1    Peters, N.C.2    Afrin, F.3    Mendez, S.4    Bertholet, S.5    Belkaid, Y.6    Sacks, D.L.7
  • 32
    • 17444429293 scopus 로고    scopus 로고
    • Second-generation vaccines against leishmaniasis
    • Coler, R. N. and Reed, S. G., Second-generation vaccines against leishmaniasis. Trends Parasitol. 2005. 21: 244-249.
    • (2005) Trends Parasitol , vol.21 , pp. 244-249
    • Coler, R.N.1    Reed, S.G.2
  • 33
    • 0031934169 scopus 로고    scopus 로고
    • Vaccination of langur monkeys (Presbytis entellus) against Leishmania donovani with autoclaved L. major plus BCG
    • Dube, A., Sharma, P., Srivastava, J. K., Misra, A., Naik, S. and Katiyar, J. C., Vaccination of langur monkeys (Presbytis entellus) against Leishmania donovani with autoclaved L. major plus BCG. Parasitology 1998. 116: 219-221.
    • (1998) Parasitology , vol.116 , pp. 219-221
    • Dube, A.1    Sharma, P.2    Srivastava, J.K.3    Misra, A.4    Naik, S.5    Katiyar, J.C.6
  • 34
    • 0035858116 scopus 로고    scopus 로고
    • Successful vaccination against Leishmania donovani infection in Indian langur using alum-precipitated autoclaved Leishmania major with BCG
    • Misra, A., Dube, A., Srivastava, B., Sharma, P., Srivastava, J. K., Katiyar, J. C. and Naik, S., Successful vaccination against Leishmania donovani infection in Indian langur using alum-precipitated autoclaved Leishmania major with BCG. Vaccine 2001. 19: 3485-3492.
    • (2001) Vaccine , vol.19 , pp. 3485-3492
    • Misra, A.1    Dube, A.2    Srivastava, B.3    Sharma, P.4    Srivastava, J.K.5    Katiyar, J.C.6    Naik, S.7
  • 36
    • 1542360794 scopus 로고    scopus 로고
    • Safety, immunogenecity, and efficacy of an autoclaved Leishmania amazonensis vaccine plus BCG adjuvant against New World cutaneous leishmaniasis
    • Armijos, R. X., Weigel, M. M., Calvopina, M., Hidalgo, A., Cevallos, W. and Correa, J., Safety, immunogenecity, and efficacy of an autoclaved Leishmania amazonensis vaccine plus BCG adjuvant against New World cutaneous leishmaniasis. Vaccine 2004. 22: 1320-1326.
    • (2004) Vaccine , vol.22 , pp. 1320-1326
    • Armijos, R.X.1    Weigel, M.M.2    Calvopina, M.3    Hidalgo, A.4    Cevallos, W.5    Correa, J.6
  • 37
    • 0035253601 scopus 로고    scopus 로고
    • The hamster as a model of human visceral leishmaniasis: Progressive disease and impaired generation of nitric oxide in the face of a prominent Th1-like cytokine response
    • Melby, P. C., Chandrasekar, B., Zhao, W. and Coe, J. E., The hamster as a model of human visceral leishmaniasis: Progressive disease and impaired generation of nitric oxide in the face of a prominent Th1-like cytokine response. J. Immunol. 2001. 166: 1912-1920.
    • (2001) J. Immunol , vol.166 , pp. 1912-1920
    • Melby, P.C.1    Chandrasekar, B.2    Zhao, W.3    Coe, J.E.4
  • 38
    • 33644928988 scopus 로고    scopus 로고
    • Leishmania donovani: Identification of stimulatory soluble antigenic proteins using cured human and hamster lymphocytes for their prophylactic potential against visceral leishmaniasis
    • Garg, R., Gupta, S. K., Tripathi, P., Hajela, K., Sundar, S., Naik, S. and Dube, A., Leishmania donovani: Identification of stimulatory soluble antigenic proteins using cured human and hamster lymphocytes for their prophylactic potential against visceral leishmaniasis. Vaccine 2006. 24: 2900-2909.
    • (2006) Vaccine , vol.24 , pp. 2900-2909
    • Garg, R.1    Gupta, S.K.2    Tripathi, P.3    Hajela, K.4    Sundar, S.5    Naik, S.6    Dube, A.7
  • 39
    • 0028940974 scopus 로고
    • The role of the innate immune response in Th1 cell development following Leishmania major infection
    • Scharton-Kersten, T. and Scott, P., The role of the innate immune response in Th1 cell development following Leishmania major infection. J. Leukoc. Biol. 1995. 57: 515-522.
    • (1995) J. Leukoc. Biol , vol.57 , pp. 515-522
    • Scharton-Kersten, T.1    Scott, P.2
  • 40
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immuno-regulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G., Interleukin-12: A proinflammatory cytokine with immuno-regulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 1995. 13: 251-276.
    • (1995) Annu. Rev. Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 41
    • 0031910758 scopus 로고    scopus 로고
    • Splenic cytokine responses in Indian kala-azar before and after treatment
    • Kenney, R. T., Sacks, D. L., Gam, A. A., Murray, H. W. and Sundar, S., Splenic cytokine responses in Indian kala-azar before and after treatment. J. Infect. Dis. 1998. 177: 815-818.
    • (1998) J. Infect. Dis , vol.177 , pp. 815-818
    • Kenney, R.T.1    Sacks, D.L.2    Gam, A.A.3    Murray, H.W.4    Sundar, S.5
  • 43
    • 1842338027 scopus 로고    scopus 로고
    • Interleukin-10 and interleukin-4 inhibit intracellular killing of Leishmania infantum and Leishmania major by human macrophages by decreasing nitric oxide generation
    • Vouldoukis, I., Becherel, P. A., Riveros-Moreno, V., Arock, M., da Silva, O., Debre, P., Mazier, D. and Mossalayi, M. D., Interleukin-10 and interleukin-4 inhibit intracellular killing of Leishmania infantum and Leishmania major by human macrophages by decreasing nitric oxide generation. Eur. J. Immunol. 1997. 27: 860-865.
    • (1997) Eur. J. Immunol , vol.27 , pp. 860-865
    • Vouldoukis, I.1    Becherel, P.A.2    Riveros-Moreno, V.3    Arock, M.4    da Silva, O.5    Debre, P.6    Mazier, D.7    Mossalayi, M.D.8
  • 45
    • 34547578743 scopus 로고    scopus 로고
    • Leishmanial antigens in liposomes promote protective immunity and provide immunotherapy against visceral leishmaniasis via polarized Th1 response
    • Bhowmick, S., Ravindran, R. and Ali, N., Leishmanial antigens in liposomes promote protective immunity and provide immunotherapy against visceral leishmaniasis via polarized Th1 response. Vaccine 2007. 25: 6544-6556.
    • (2007) Vaccine , vol.25 , pp. 6544-6556
    • Bhowmick, S.1    Ravindran, R.2    Ali, N.3
  • 46
    • 0026586443 scopus 로고
    • Selective inability of spleen antigen presenting cells from Leishmania donovani infected hamsters to mediate specific T cell proliferation to parasite antigens
    • Rodrigues, V., Jr., Da Silva, J. S. and Campos-Neto, A., Selective inability of spleen antigen presenting cells from Leishmania donovani infected hamsters to mediate specific T cell proliferation to parasite antigens. Parasite Immunol. 1992. 14: 49-58.
    • (1992) Parasite Immunol , vol.14 , pp. 49-58
    • Rodrigues Jr., V.1    Da Silva, J.S.2    Campos-Neto, A.3
  • 47
    • 18944378937 scopus 로고    scopus 로고
    • Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: Evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis
    • Basu, R., Bhaumik, S., Basu, J. M., Naskar, K., De, T. and Roy, S., Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: Evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis. J. Immunol. 2005. 174: 7160-7171.
    • (2005) J. Immunol , vol.174 , pp. 7160-7171
    • Basu, R.1    Bhaumik, S.2    Basu, J.M.3    Naskar, K.4    De, T.5    Roy, S.6
  • 48
    • 0018849566 scopus 로고
    • Immunological responses of L. donovani infection in mice and significance of T cell in resistance to experimental leishmaniasis
    • Rezai, H. R., Farrell, J. and Soulsby, E. L., Immunological responses of L. donovani infection in mice and significance of T cell in resistance to experimental leishmaniasis. Clin. Exp. Immunol. 1980. 40: 508-514.
    • (1980) Clin. Exp. Immunol , vol.40 , pp. 508-514
    • Rezai, H.R.1    Farrell, J.2    Soulsby, E.L.3
  • 49
    • 0030248690 scopus 로고    scopus 로고
    • Leishmaniasis: Immunological and clinical aspects and vaccines in Venezuela
    • Convit, J., Leishmaniasis: Immunological and clinical aspects and vaccines in Venezuela. Clin. Dermatol. 1996. 14: 479-487.
    • (1996) Clin. Dermatol , vol.14 , pp. 479-487
    • Convit, J.1
  • 50
    • 0019301138 scopus 로고
    • Immunological regulation of experimental cutaneous leishmaniasis. 1. Immunogenetic aspects of susceptibility to Leishmania tropica in mice
    • Howard, J. G., Hale, C. and Chan-Liew, W. L., Immunological regulation of experimental cutaneous leishmaniasis. 1. Immunogenetic aspects of susceptibility to Leishmania tropica in mice. Parasite Immunol. 1980. 2: 303-314.
    • (1980) Parasite Immunol , vol.2 , pp. 303-314
    • Howard, J.G.1    Hale, C.2    Chan-Liew, W.L.3
  • 51
    • 0024236111 scopus 로고
    • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
    • Scott, P., Natovitz, P., Coffman, R. L., Pearce, E. and Sher, A., Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J. Exp. Med. 1988. 168: 1675-1684.
    • (1988) J. Exp. Med , vol.168 , pp. 1675-1684
    • Scott, P.1    Natovitz, P.2    Coffman, R.L.3    Pearce, E.4    Sher, A.5
  • 52
    • 0022375891 scopus 로고
    • Adoptive transfer of vaccine-induced resistance to Leishmania donovani
    • Jarecki-Black, J. C., Glassman, A. B. and James, E. R., Adoptive transfer of vaccine-induced resistance to Leishmania donovani. Am. J. Trop. Med. Hyg. 1985. 34: 1095-1097.
    • (1985) Am. J. Trop. Med. Hyg , vol.34 , pp. 1095-1097
    • Jarecki-Black, J.C.1    Glassman, A.B.2    James, E.R.3
  • 53
    • 0024412321 scopus 로고
    • Characterization of protective T cells in the acquired response to Leishmania donovani in genetically determined cure (H-2b) and noncure (H-2d) mouse strains
    • Ulczak, O. M., Ghadirian, E., Skamene, E., Blackwell, J. M. and Kongshavn, P. A., Characterization of protective T cells in the acquired response to Leishmania donovani in genetically determined cure (H-2b) and noncure (H-2d) mouse strains. Infect. Immun. 1989. 57: 2892-2899.
    • (1989) Infect. Immun , vol.57 , pp. 2892-2899
    • Ulczak, O.M.1    Ghadirian, E.2    Skamene, E.3    Blackwell, J.M.4    Kongshavn, P.A.5
  • 54
    • 29644446928 scopus 로고    scopus 로고
    • Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen
    • Polley, R., Stager, S., Prickett, S., Maroof, A., Zubairi, S., Smith, D. F. and Kaye, P. M., Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen. Infect. Immun. 2006. 74: 773-776.
    • (2006) Infect. Immun , vol.74 , pp. 773-776
    • Polley, R.1    Stager, S.2    Prickett, S.3    Maroof, A.4    Zubairi, S.5    Smith, D.F.6    Kaye, P.M.7
  • 55
    • 16244405883 scopus 로고    scopus 로고
    • Immunostimulatory cellular responses of cured Leishmania-infected patients and hamsters against the integral membrane proteins and non-membranous soluble proteins of a recent clinical isolate of Leishmania donovani
    • Garg, R., Gupta, S. K., Tripathi, P., Naik, S., Sundar, S. and Dube, A., Immunostimulatory cellular responses of cured Leishmania-infected patients and hamsters against the integral membrane proteins and non-membranous soluble proteins of a recent clinical isolate of Leishmania donovani. Clin. Exp. Immunol. 2005. 140: 149-156.
    • (2005) Clin. Exp. Immunol , vol.140 , pp. 149-156
    • Garg, R.1    Gupta, S.K.2    Tripathi, P.3    Naik, S.4    Sundar, S.5    Dube, A.6
  • 57
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
    • Ding, A. H., Nathan, C. F. and Stuehr, D. J., Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 1988. 141: 2407-2412.
    • (1988) J. Immunol , vol.141 , pp. 2407-2412
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.