Use of magnetic nanoparticles to monitor alginate-encapsulated βTC-tet cells

Magnetic Resonance in Medicine

Volumn 61, Issue 2, 2009, Pages 282-290

  Constantinidis, Ioannis ^a,b   Grant, Samuel C ^b,c,d   Simpson, Nicholas E ^a   Oca Cossio, Jose A ^a   Sweeney, Carol A ^a   Mao, Hui ^e   Blackband, Stephen J ^b,c   Sambanis, Athanassios ^f  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b FLORIDA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d FAMU FSU COLLEGE OF ENGINEERING   (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Georgia Institute of Technology   (United States)

Author keywords

Alginate; Cell encapsulation; MION; Tissue engineering; Tc tet

Indexed keywords

ALGINATE; CELL PROLIFERATION; CELLS; CYTOLOGY; IRON OXIDES; MAGNETIC NANOPARTICLES; MAGNETIC RESONANCE IMAGING; MOLECULAR IMAGING; NUCLEAR MAGNETIC RESONANCE; TISSUE; TISSUE ENGINEERING;

CELL ENCAPSULATIONS; EXTRACELLULAR COMPARTMENTS; INTRACELLULAR COMPARTMENTS; MION; MONOCRYSTALLINE IRON OXIDE NANOPARTICLE; NON-INVASIVE MONITORING; THERAPEUTIC EFFICACY; TISSUE ENGINEERED CONSTRUCTS;

CELL ENGINEERING;

ALGINIC ACID; MONOCRYSTALLINE IRON OXIDE NANOPARTICLE; POLYLYSINE;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL GROWTH; CELLULAR DISTRIBUTION; CHEMICAL LABELING; CONTROLLED STUDY; ENCAPSULATION; INTRACELLULAR SPACE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; TISSUE ENGINEERING;

EID: 60549097537     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.21833     Document Type: Article

References (44)

1. Kirkpatrick SJ, Hinds MT, Duncan DD. Acousto-optical characterization of the viscoelastic nature of a nuchal elastin tissue scaffold. Tissue Eng 2003;9:645-656.
2. Mason C, Markusen JF, Town MA, Dunnill P, Wang RK. The potential of optical coherence tomography in the engineering of living tissue. Phys Med Biol 2004;49:1097-1115.
3. Mertsching H, Walles T, Hofmann M, Schanz J, Knapp WH. Engineering of a vascularized scaffold for artificial tissue and organ generation. Biomaterials 2005;26:6610-6617.
4. Guldberg RE, Ballock RT, Boyan BD, Duvall CL, Lin AS, Nagaraja S, Oest M, Phillips J, Porter BD, Robertson G, Taylor WR. Analyzing bone, blood vessels, and biomaterials with microcomputed tomography. IEEE Eng Med Biol Mag 2003;22:77-83.
5. Jones AC, Milthorpe B, Averdunk H, Limaye A, Senden TJ, Sakellariou A, Sheppard AP, Sok RM, Knackstedt MA, Brandwood A, Rohner D, Hutmacher DW. Analysis of 3D bone ingrowth into polymer scaffolds via micro-computed tomography imaging. Biomaterials 2004;25:4947-4954.
6. Constantinidis I, Sambanis A. Non-invasive monitoring of tissue engineered constructs by nuclear magnetic resonance methodologies. Tissue Eng 1998;4:9-17.
7. Hartman EH, Pikkemaat JA, Vehof JW, Heerschap A, Jansen JA, Spauwen PH. In vivo magnetic resonance imaging explorative study of ectopic bone formation in the rat. Tissue Eng 2002;8:1029-1036.
8. Neves AA, Medcalf N, Brindle K. Functional assessment of tissue-engineered meniscal cartilage by magnetic resonance imaging and spectroscopy. Tissue Eng 2003;9:51-62.
9. Burg KJ, Delnomdedieu M, Beiler RJ, Culberson CR, Greene KG, Halberstadt CR, Holder WDJ, Loebsack AB, Roland WD, Johnson GA. Application of magnetic resonance microscopy to tissue engineering: a polylactide model. J Biomed Mater Res 2002;61:380-390.
10. 1H NMR spectroscopy. Cell Transplantation 2005;14:139-149.
11. Stabler CL, Long Jr RC, Sambanis A, Constantinidis I. Noninvasive measurement of viable cell number in tissue engineered constructs in vitro using 1H NMR spectroscopy. Tissue Eng 2005;11:404-414.
12. Modo M, Hoehn M, Bulte JW. Cellular MR imaging. Mol Imaging 2005;4:143-164.
13. Weissleder R, Cheng HC, Bogdanova A, Bogdanov AJ. Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging 1997;7:258-263.
14. Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, White DL, Jacobs P, Lewis J. Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol 1989;152:167-173.
15. Dodd SJ, Williams M, Suhan JP, Williams DS, Koretsky AP, Ho C. Detection of single mammalian cells by high-resolution magnetic resonance imaging. Biophys J 1999;76:103-109.
16. Foster-Gareau P, Heyn C, Alejski A, Rutt BK. Imaging single cells with a 1.5T clinical MRI scanner. Magn Reson Med 2003;49:968-971.
17. Evgenov NV, Medarova Z, Dai G, Bonner-Weir S, Moore A. In vivo imaging of islet transplantation. Nat Med 2006;12:144-148.
18. Kriz J, Jirak D, Girman P, Berkova Z, Zacharovova K, Honsova E, Lodererova A, Hajek M, Saudek F. Magnetic resonance imaging of pancreatic islets in tolerance and rejection. Transplantation 2005;80:1596-1603.
19. Cahill KS, Gaidosh G, Huard J, Silver X, Byrne BJ, Walter GA. Nonin-vasive monitoring and tracking of muscle stem cell transplants. Transplantation 2004;78:1626-1633.
20. Gupta AK, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 2005;26:3995-4021.
21. Terrovitis JV, Bulte JW, Sarvananthan S, Crowe LA, Sarathchandra P, Batten P, Sachlos E, Chester AH, Czernuszka JT, Firmin DN, Taylor PM, Yacoub MH. Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering. Tissue Eng 2006;12:2765-2775.
22. Ito A, Shinkai M, Honda H, Kobayashi T. Medical application of functionalized magnetic nanoparticles. J Biosci Bioeng 2005;100:1-11.
23. Dobson J, Cartmell SH, Keramane A, El Haj AJ. Principles and design of a novel magnetic force mechanical conditioning bioreactor for tissue engineering, stem cell conditioning, and dynamic in vitro screening. IEEE Trans Nanobiosci 2006;5:173-177.
24. Ino K, Ito A, Honda H. Cell patterning using magnetite nanoparticles and magnetic force. Biotechnol Bioeng 2007;97:1309-1317.
25. Fleischer N, Chen C, Surana M, Leiser M, Rossetti L, Pralong W, Efrat S. Functional analysis of a conditionally transformed pancreatic β-cell line. Diabetes 1998;47:1419-1425.
26. Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980;210:908-910.
27. Sun A.M. Microencapsulation of pancreatic islet cells: a bioartificial endocrine pancreas. Methods Enzymol 1988;137:575-580.
28. i on the mechanism of insulin secretion in the mouse insulinoma βTC3 cell line. Biochem J 1997;326:807-814.
29. Stabler C, Wilks K, Sambanis A, Constantinidis I. The effects of alginate composition on encapsulated βTC3 cells. Biomaterials 2001;22:1301-1310.
30. Sambanis A, Papas KK, Flanders PC, Long Jr RC, Kang H, Constantinidis I. Towards the development of a bioartificial pancreas: immunoiso-lation and NMR monitoring of mouse insulinomas. Cytotechnology 1994;15:351-363.
31. Oca-Cossio J, Mao H, Khokhlova N, Kennedy CM, Kennedy JW, Stabler CL, Hao E, Sambanis A, Simpson NE, Constantinidis I. Magnetically labeled insulin-secreting cells. Biochem Biophys Res Commun 2004;319:569-575.
32. Webb AG, Grant SC. Signal-to-noise and magnetic susceptibility tradeoffs in solenoidal microcoils for NMR. J Magn Reson Part B 1996;113: 83-87.
33. Marquardt DW. An algorithm for least-squares estimation of nonlinear parameters. J Soc Ind App Math 1963;11:431-441.
34. Simpson NE, Khokhlova N, Oca-Cossio JA, McFarlane SS, Simpson CP, Constantinidis I. Effects of regulating conditionally-transformed alginate-entrapped insulin secreting cell lines in vitro. Biomaterials 2005;26:4633-4641.
35. Cheng S-Y, Constantinidis I, Sambanis A. Insulin secretion dynamics of free and alginate-encapsulated insulinoma cells. Cytotechnology 2006;51:159-170.
36. Constantinidis I, Rask I, Long Jr RC, Sambanis A. Effects of alginate encapsulation on the metabolic, secretory, and growth characteristics of entrapped βTC3 mouse insulinoma cells. Biomaterials 1999;20:2019-2027.
37. Papas KK, Long Jr RC, Constantinidis I, Sambanis A. Development of a bioartificial pancreas: I. Long-term propagation and basal and induced secretion from entrapped βTC3 cell cultures. Biotechnol Bioeng 1999;66:219-230.
38. Gross JD, Constantinidis I, Sambanis A. Modeling of encapsulated cell systems. J Theor Biol 2007;244:500-510.
39. Koenig SH, Brown 3rd RD. Relaxation of solvent protons by paramagnetic ions and its dependence on magnetic field and chemical environment: implications for NMR imaging. Magn Reson Med 1984;1:478-495.
40. Gillis P, Koenig SH. Transverse relaxation of solvent protons induced by magnetized spheres: application to ferritin, erythrocytes, and magnetite. Magn Reson Med 1987;5:323-345.
41. Koenig SH, Gillis P. Transverse relaxation (1/T2) of solvent protons induced by magnetized spheres and its relevance to contrast enhancement in MRI. Invest Radiol 1988;23:S224-S228.
42. Delikatny EJ, Poptani H. MR techniques for in vivo molecular and cellular imaging. Radiol Clin North Am 2005;43:205-220.
43. Burtea C, Laurent S, Vander Elst L, Muller RN. Contrast agents: magnetic resonance. Handb Exp Pharmacol 2008;185:135-165.
44. Jirak D, Kriz J, Herynek V, Andersson B, Girman P, Burian M, Saudek F, Hajek M. MRI of transplanted pancreatic islets. Magn Reson Med 2004;52:1228-1233.