A new redox-dependent mechanism of MMP-1 activity control comprising reduced low-molecular-weight thiols and oxidizing radicals

Journal of Molecular Medicine

Volumn 87, Issue 3, 2009, Pages 261-272

  Koch, Sabine ^a,b   Volkmar, Christine M ^c   Kolb Bachofen, Victoria ^b   Korth, Hans Gert ^d   Kirsch, Michael ^e   Horn, Anselm H C ^f   Sticht, Heinrich ^f   Pallua, Norbert ^c   Suschek, Christoph V ^c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e UNIVERSITY HOSPITAL ESSEN   (Germany)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Glutathione; MMP 1; Nitric oxide; Nitrite; UVA

Indexed keywords

ACETYLCYSTEINE; ASCORBIC ACID; CYSTEINE; GLUTATHIONE; HOMOCYSTEIC ACID; INTERSTITIAL COLLAGENASE; NITRIC OXIDE; NITRITE; NITROGEN DIOXIDE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TROLOX C;

ARTICLE; CONTROLLED STUDY; DERIVATIZATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; OXIDATION REDUCTION REACTION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; ULTRAVIOLET A RADIATION;

ANTIOXIDANTS; ASCORBIC ACID; BLOTTING, WESTERN; CATALYSIS; CELLS, CULTURED; CHROMANS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FLUORESCENCE; FREE RADICALS; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMANS; KINETICS; MATRIX METALLOPROTEINASE 1; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NITRITES; OXIDATION-REDUCTION; PEPTIDES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS; ULTRAVIOLET RAYS;

EID: 60549091548     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-008-0420-5     Document Type: Article

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