Synthesis of sulfonyl curcumin mimics exerting a vasodilatation effect on the basilar artery of rabbits

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 5, 2009, Pages 1481-1483

  Ahn, Chan Mug ^a   Park, Byong Gon ^b   Woo, Ho Bum ^a   Ham, Jungyeob ^c   Shin, Woon Seob ^b   Lee, Seokjoon ^b  

^a Yonsei University Wonju College of Medicine   (South Korea)

^b Kwandong University College of Medicine   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

Basilar artery; Curcumin; Organic synthesis; Sulfonyl curcumin mimics; Vasodilatation

Indexed keywords

AMIDE; CURCUMIN; SULFANILAMIDE;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; BASILAR ARTERY; COMPARATIVE STUDY; CONCENTRATION RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; MALE; NONHUMAN; RABBIT; VASCULAR DISEASE;

ANIMALS; BASILAR ARTERY; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MOLECULAR MIMICRY; RABBITS; SULFINIC ACIDS; VASODILATION; VASODILATOR AGENTS;

ORYCTOLAGUS CUNICULUS;

EID: 60449116666     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.01.019     Document Type: Article

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19. + solution (50 mM), which was prepared by replacing NaCl with an equimolar concentration of KCl in PSS, until the responses became stable.
20. Structure of asymmetric alkyl or aryl amide curcumin mimics with weak vasodilatation effect on the basilar artery of the rabbits.{A figure is presented}