The CYP26 inhibitor R115866 potentiates the effects of all-trans retinoic acid on cultured human epidermal keratinocytes

British Journal of Dermatology

Volumn 160, Issue 3, 2009, Pages 505-513

  Giltaire, S ^a   Herphelin, F ^a   Frankart, A ^a   Herin M ^a   Stoppie, P ^b   Poumay, Y ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b Barrier Therapeutics NV   (Belgium)

Author keywords

Epidermal differentiation; HB EGF; Keratinocyte; R115866; Retinoic acid

Indexed keywords

CYTOCHROME P450 26A1; CYTOKERATIN 10; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INVOLUCRIN; MESSENGER RNA; N [4 [2 ETHYL 1 (1H 1,2,4 TRIAZOL 1 YL)BUTYL]PHENYL] 2 BENZOTHIAZOLAMINE; RETINOIC ACID;

ARTICLE; AUTOCRINE EFFECT; DRUG EFFECT; DRUG POTENTIATION; EPIDERMIS CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; KERATINOCYTE; METABOLISM; PRIORITY JOURNAL;

ADULT; BENZOTHIAZOLES; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INHIBITORS; EPIDERMIS; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATIN-10; KERATINOCYTES; PROTEIN PRECURSORS; TRETINOIN; TRIAZOLES;

EID: 60449106395     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2008.08960.x     Document Type: Article

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