Rehabilitation of hemianopia

Current Opinion in Neurology

Volumn 22, Issue 1, 2009, Pages 36-40

  Schofield, Thomas M ^a   Leff, Alexander P ^a,b,c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c WTCN   (United Kingdom)

Author keywords

Eye movements; Homonymous hemianopia; Optical; Restoration; Treatment; Vision

Indexed keywords

BEHAVIOR THERAPY; BINOCULAR VISION; EVIDENCE BASED MEDICINE; EYE FIXATION; EYE MOVEMENT; HOMONYMOUS HEMIANOPIA; HUMAN; READING; REHABILITATION CARE; REVIEW; TREATMENT OUTCOME; VISUAL FIELD; VISUAL FIELD RESTITUTION THERAPY;

EYE MOVEMENTS; HEMIANOPSIA; HUMANS; VISUAL FIELDS; VISUAL PERCEPTION;

EID: 60449106017     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/WCO.0b013e32831f1b2c     Document Type: Review

References (52)

1. Zhang X, Kedar S, Lynn MJ, et al. Homonymous hemianopias: clinical-anatomic correlations in 904 cases. Neurology 2006; 66:906-910.
2. Zhang X, Kedar S, Lynn MJ, et al. Natural history of homonymous hemianopia. Neurology 2006; 66:901-905.
3. Friedman PJ. Stroke outcome in elderly people living alone. Disabil Rehabil 1995; 17:90-93.
4. Gray CS, French JM, Bates D, et al. Recovery of visual fields in acute stroke: homonymous hemianopia associated with adverse prognosis. Age Ageing 1989; 18:419-421.
5. Han L, Law-Gibson D, Reding M. Key neurological impairments influence function-related group outcomes after stroke. Stroke 2002; 33:1920-1924.
6. Peli E. Field expansion for homonymous hemianopia by optically induced peripheral exotropia. Optom Vis Sci 2000; 77:453-464.
7. Bowers AR, Keeney K, Peli E. Community-based trial of a peripheral prism visual field expansion device for hemianopia. Arch Ophthalmol 2008; 126:657-664. Certainly, the largest study ever published on therapy for hemianopia (n = 214 with homonymous hemianopia). Whatever the mechanism, this study confirms that VRT can have a meaningful effect on visual function in patients with a HVFD.
8. Martin T, Riley ME, Kelly KN, et al. Visually-guided behavior of homonymous hemianopes in a naturalistic task. Vision Res 2007; 47:3434-3446.
9. Pambakian AL, Wooding DS, Patel N, et al. Scanning the visual world: a study of patients with homonymous hemianopia. J Neural Neurosurg Psychiatry 2000; 69:751-759.
10. Zangemeister WH, Oechsner U, Freksa C. Short-term adaptation of eye movements in patients with visual hemifield defects indicates high level control of human scanpath. Optom Vis Sci 1995; 72:467-477.
11. Kerkhoff G, Bucher L. Line bisection as an early method to assess homon-ymous hemianopia. Cortex 2008; 44:200-205.
12. Nelles G, Esser J, Eckstein A, et al. Compensatory visual field training for patients with hemianopia after stroke. Neurosci Lett 2001; 306:189-192.
13. Pambakian AL, Mannan SK, Hodgson TL, Kennard C. Saccadic visual search training: a treatment for patients with homonymous hemianopia. J Neurol Neurosurg Psychiatry 2004; 75:1443-1448.
14. Henson DB. Corrective saccades: effects of altering visual feedback. Vision Res 1978; 18:63-67.
15. Jacquin-Courtois S, Bays P, Leff A, Husain M. Rehabilitation for visual field defects: a dynamic ramp-step search paradigm. J Rehabil Med 2008; 547:129.
16. Bhogal SK, Teasell R, Speechley M. Intensity of aphasia therapy, impact on recovery. Stroke 2003; 34:987-993.
17. Leff AP, Scott SK, Crewes H, et al. Impaired reading in patients with right hemianopia. Ann Neurol 2000; 47:171-178.
18. Zihl J. Eye movement patterns in hemianopic dyslexia. Brain 1995; 118:891-912.
19. Kang TJ, Muter P. Reading dynamically displayed text. Behav Inf Technol 1989; 8:33-42.
20. Kerkhoff G, Munssinger U, Haaf E, et al. Rehabilitation of homonymous scotomas in patients with postgeniculate damage of the visual-system: saccadic compensation training. Restor Neurol Neurosci 1992; 4:245-254.
21. McDonald SA, Spitsyna G, Shillcock RC, et al. Patients with hemianopic alexia adopt an inefficient eye movement strategy when reading text. Brain 2006; 129:158-167.
22. Spitzyna GA, Wise RJ, McDonald SA, et al. Optokinetic therapy improves text reading in patients with hemianopic alexia: a controlled trial. Neurology 2007; 68:1922-1930. A study of optokinetic nystagmus inducing therapy for hemianopic alexia that largely recapitulates previous findings, but in the context of a controlled trial. Changes in eye movement parameters, including increased amplitude of reading saccades into the damaged but not the undamaged hemifield, correlated with improvements in (oral) text reading speed.
23. Buttner-Ennever JA, Horn AK. Anatomical substrates of oculomotor control. Curr Opin Neurobiol 1997; 7:872-879.
24. Moschovakis AK, Scudder CA, Highstein SM. The microscopic anatomy and physiology of the mammalian saccadic system. Prog Neurobiol 1996; 50:133-254.
25. Schuett S, Heywood CA, Kentridge RW, Zihl J. The significance of visual information processing in reading: insights from hemianopic dyslexia. Neuropsychologia 2008; 46:2445-2462. A comprehensive, well written and balanced review of research into hemianopic alexia from its initial description (1881) to the present day.
26. Rutishauser U, Koch C. Probabilistic modeling of eye movement data during conjunction search via feature-based attention. J Vis 2007; 7:5.
27. Schuett S, Heywood CA, Kentridge RW, Zihl J. Rehabilitation of hemianopic dyslexia: are words necessary for re-learning oculomotor control? Brain 2008 [Epub ahead of print], doi: 10.1093/brain/awn285.
28. Mueller I, Mast H, Sabel BA. Recovery of visual field defects: a large clinical observational study using vision restoration therapy. Restor Neurol Neurosci 2007; 25:563-572. A nicely carried out, community-based study (n = 43); it demonstrates the functional utility and general acceptability of monocular, peripheral prism glasses as a mobility aid for patients with hemianopia.
29. Sahraie A, Trevethan CT, MacLeod MJ, et al. Increased sensitivity after repeated stimulation of residual spatial channels in blindsight. Proc Natl Acad Sci U S A 2006; 103:14971-14976.
30. Schmielau F, Wong EK Jr. Recovery of visual fields in brain-lesioned patients by reaction perimetry treatment. J Neuroeng Rehabil 2007; 4:31.
31. Kasten E, Wust S, Behrens-Baumann W, Sabel BA. Computer-based training for the treatment of partial blindness. Nat Med 1998; 4:1083-1087.
32. Sabel BA. Vision restoration therapy and raising red flags too early. Br J Ophthalmol 2006; 90:659-660.
33. Glisson CC. Capturing the benefit of vision restoration therapy. Curr Opin Ophthalmol 2006; 17:504-508.
34. Horton JC. Disappointing results from Nova Vision's visual restoration therapy. Br J Ophthalmol 2005; 89:1-2.
35. Horton JC. Vision restoration therapy: confounded by eye movements. Br J Ophthalmol 2005; 89:792-794.
36. McFadzean RM. NovaVision: vision restoration therapy. Curr Opin Ophthalmol 2006; 17:498-503.
37. Pambakian A, Currie J, Kennard C. Rehabilitation strategies for patients with homonymous visual field defects. J Neuroophthalmol 2005; 25:136-142.
38. Pelak VS, Dubin M, Whitney E. Homonymous hemianopia: a critical analysis of optical devices, compensatory training, and NovaVision. Curr Treat Options Neurol 2007; 9:41-47.
39. Plant GT. A work out for hemianopia. Br J Ophthalmol 2005; 89:2.
40. Sabel BA, Kenkel S, Kasten E. Vision restoration therapy. Br J Ophthalmol 2005; 89:522-524.
41. Reinhard J, Schreiber A, Schiefer U, et al. Does visual restitution training change absolute homonymous visual field defects? A fundus controlled study. Br J Ophthalmol 2005; 89:30-35.
42. Sabel BA, Kenkel S, Kasten E. Vision restoration therapy (VRT) efficacy as assessed by comparative perimetric analysis and subjective questionnaires. Restor Neurol Neurosci 2004; 22:399-420.
43. Schreiber A, Vonthein R, Reinhard J, et al. Effect of visual restitution training on absolute homonymous scotomas. Neurology 2006; 67:143-145.
44. Duffau H. Brain plasticity: from pathophysiological mechanisms to therapeutic applications. J Clin Neurosci 2006; 13:885-897.
45. Cowey A. The 30th Sir Frederick Bartlett lecture. Fact, artefact, and myth about blindsight. Q J Exp Psychol A 2004; 57:577-609.
46. Sahraie A, Trevethan CT, MacLeod MJ. Temporal properties of spatial channel of processing in hemianopia. Neuropsychologia 2008; 46:879-885. Three experiments performed across eight cortically blind patients demonstrate the optimum spatial and temporal characteristics that stimuli should have for investigating blindsight.
47. Henriksson L, Raninen A, Nasanen R, et al. Training-induced cortical representation of a hemianopic hemifield. J Neurol Neurosurg Psychiatry 2007; 78:74-81.
48. Marshall RS, Ferrera JJ, Barnes A, et al. Brain activity associated with stimulation therapy of the visual borderzone in hemianopic stroke patients. Neurorehabil Neural Repair 2008; 22:136-144.
49. Nelles G, de Greift A, Pscherer A, et al. Cortical activation in hemianopia after stroke. Neurosci Lett 2007; 426:34-38. A meticulously carried out experiment on two hemianopic patients who underwent training using flicker stimuli. Long-term training improved residual visual function (as measured using flicker sensitivity) and magnetoencephalography measurements, but not with Goldmann perimetry. This demonstrates how functional imaging measures, which may turn out to be very useful in charting visual field rehabilitation, can identify improvements in nonstriate vision.
50. Raninen A, Vanni S, Hyvarinen L, Nasanen R. Temporal sensitivity in a hemianopic visual field can be improved by long-term training using flicker stimulation. J Neurol Neurosurg Psychiatry 2007; 78:66-73.
51. Watanabe K, Shinoda K, Kimura I, et al. Discordance between subjective perimetric visual fields and objective multifocal visual evoked potential-determined visual fields in patients with hemianopsia. Am J Ophthalmol 2007; 143:295-304.
52. Logothetis NK. What we can do and what we cannot do with fMRI. Nature 2008; 453:869-878. A good piece of bedtime reading for those wanting to revisit exactly what neural processes are represented in functional imaging data.