Autism, fever, epigenetics and the locus coeruleus

Brain Research Reviews

Volumn 59, Issue 2, 2009, Pages 388-392

  Mehler, Mark F ^a   Purpura, Dominick P ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Developmental critical period; Gene environmental interaction; Homeostatic signal; Imprinted gene; Neuromodulator; Pharmacoepigenomic agent; Prenatal stressor; Sensorimotor processing

Indexed keywords

POSTSYNAPTIC RECEPTOR; PRESYNAPTIC RECEPTOR;

AUTISM; COGNITION; EPIGENETICS; FEVER; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; LOCUS CERULEUS; MATERNAL STRESS; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NEUROMODULATION; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; AUTISTIC DISORDER; EPIGENESIS, GENETIC; FEMALE; FEVER; HUMANS; LOCUS COERULEUS; NERVE NET; NEURAL PATHWAYS; NEURONAL PLASTICITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; STRESS, PSYCHOLOGICAL;

EID: 60449085427     PISSN: 01650173     EISSN: 18726321     Source Type: Journal    
DOI: 10.1016/j.brainresrev.2008.11.001     Document Type: Review

References (39)

1. Abrahams B.S., and Geschwind D.H. Advances in autism genetics: on the threshold of a new neurobiology. Nat. Rev., Genet. 9 (2008) 341-355
2. Alikhani-Koopaei R., Fouladkou F., Frey F.J., and Frey B.M. Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. J. Clin. Invest. 114 (2004) 1146-1157
3. Almeida M.C., Steiner A.A., Coimbra N.C., and Branco L.G. Thermoeffector neuronal pathways in fever: a study in rats showing a new role of the locus coeruleus. J. Physiol. 558 (2004) 283-294
4. Amaral D.G., Schumann C.M., and Nordahl C.W. Neuroanatomy of autism. Trends Neurosci. 31 (2008) 137-145
5. Aston-Jones G., and Cohen J.D. An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. Annu. Rev. Neurosci. 28 (2005) 403-450
6. Badcock C., and Crespi B. Imbalanced genomic imprinting in brain development: an evolutionary basis for the aetiology of autism. J. Evol. Biol. 19 (2006) 1007-1032
7. Berridge C.W. Noradrenergic modulation of arousal. Brain Res. Rev. 58 (2008) 1-17
8. Berridge C.W., and Waterhouse B.D. The locus coeruleus-noradrenergic system. modulation of behavioral state and state-dependent cognitive processes. Brain Res. Brain Res. Rev. 42 (2003) 33-84
9. Beversdorf D.Q., Manning S.E., Hillier A., Anderson S.L., Nordgren R.E., Walters S.E., Nagaraja H.N., Cooley W.C., Gaelic S.E., and Bauman M.L. Timing of prenatal stressors and autism. J. Autism. Dev. Disord. 35 (2005) 471-478
10. Bouret S., and Sara S.J. Network reset: a simplified overarching theory of locus coeruleus noradrenaline function. Trends Neurosci. 28 (2005) 574-582
11. Chan C.S., Guzman J.N., Ilijic E., Mercer J.N., Rick C., Tkatch T., Meredith G.E., and Surmeier D.J. 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature 447 (2007) 1081-1086
12. Cheslack-Postava K., Fallin M.D., Avramopoulos D., Connors S.L., Zimmerman A.W., Eberhart C.G., and Newschaffer C.J. Beta2-adrenergic receptor gene variants and risk for autism in the AGRE cohort. Mol. Psychiatry 12 (2007) 283-291
13. Connors S.L., Crowell D.E., Eberhart C.G., Copeland J., Newschaffer C.J., Spence S.J., and Zimmerman A.W. Beta2-adrenergic receptor activation and genetic polymorphisms in autism: data from dizygotic twins. J. Child Neurol. 20 (2005) 876-884
14. Courchesne E., Pierce K., Schumann C.M., Redcay E., Buckwalter J.A., Kennedy D.P., and Morgan J. Mapping early brain development in autism. Neuron 56 (2007) 399-413
15. Curran L.K., Newschaffer C.J., Lee L.C., Crawford S.O., Johnston M.V., and Zimmerman A.W. Behaviors associated with fever in children with autism spectrum disorders. Pediatrics 120 (2007) e1386-92
16. Erickson C.A., Posey D.J., Stigler K.A., and McDougle C.J. Pharmacologic treatment of autism and related disorders. Pediatr. Ann. 36 (2007) 575-585
17. Feleder C., Perlik V., and Blatteis C.M. Preoptic norepinephrine mediates the febrile response of guinea pigs to lipopolysaccharide. Am. J. Physiol., Regul. Integr. Comp. Physiol. 293 (2007) R1135-1143
18. Fischer A., Sananbenesi F., Wang X., Dobbin M., and Tsai L.H. Recovery of learning and memory is associated with chromatin remodeling. Nature 447 (2007) 178-182
19. Foote S.L., Bloom F.E., and Aston-Jones G. Nucleus locus ceruleus: new evidence of anatomical and physiological specificity. Physiol. Rev. 63 (1983) 844-914
20. Hashemi E., Sahbaie P., Davies M.F., Clark J.D., and DeLorey T.M. Gabrb3 gene deficient mice exhibit increased risk assessment behavior, hypotonia and expansion of the plexus of locus coeruleus dendrites. Brain Res. 1129 (2007) 191-199
21. Holm P.C., Rodriguez F.J., Kele J., Castelo-Branco G., Kitajewski J., and Arenas E. BMPs, FGF8 and Wnts regulate the differentiation of locus coeruleus noradrenergic neuronal precursors. J. Neurochem. 99 (2006) 343-352
22. Holmes M.C., Abrahamsen C.T., French K.L., Paterson J.M., Mullins J.J., and Seckl J.R. The mother or the fetus? 11Beta-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids. J. Neurosci. 26 (2006) 3840-3844
23. Kinney D.K., Miller A.M., Crowley D.J., Huang E., and Gerber E. Autism prevalence following prenatal exposure to hurricanes and tropical storms in Louisiana. J. Autism Dev. Disord. 38 (2008) 481-488
24. Linthorst A.C., Flachskamm C., Holsboer F., and Reul J.M. Intraperitoneal administration of bacterial endotoxin enhances noradrenergic neurotransmission in the rat preoptic area: relationship with body temperature and hypothalamic-pituitary-adrenocortical axis activity. Eur. J. Neurosci. 7 (1995) 2418-2430
25. Martchek M., Thevarkunnel S., Bauman M., Blatt G., and Kemper T. Lack of evidence of neuropathology in the locus coeruleus in autism. Acta Neuropathol. 111 (2006) 497-499
26. McGill B.E., Bundle S.F., Yaylaoglu M.B., Carson J.P., Thaller C., and Zoghbi H.Y. Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 18267-18272
27. Mehler M.F., and Mattick J.S. Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease. Physiol. Rev. 87 (2007) 799-823
28. Moriceau S., and Sullivan R.M. Neurobiology of infant attachment. Dev. Psychobiol. 47 (2005) 230-242
29. Morrow E.M., Yoo S.Y., Flavell S.W., Kim T.K., Lin Y., Hill R.S., Mukaddes N.M., Balkhy S., Gascon G., Hashmi A., Al-Saad S., Ware J., Joseph R.M., Greenblatt R., Gleason D., Ertelt J.A., Apse K.A., Bodell A., Partlow J.N., Barry B., Yao H., Markianos K., Ferland R.J., Greenberg M.E., and Walsh C.A. Identifying autism loci and genes by tracing recent shared ancestry. Science 321 (2008) 218-223
30. Oleskevich S., Descarries L., and Lacaille J.C. Quantified distribution of the noradrenaline innervation in the hippocampus of adult rat. J. Neurosci. 9 (1989) 3803-3815
31. Ovadia H., Abramsky O., and Weidenfeld J. Evidence for the involvement of the central adrenergic system in the febrile response induced by interleukin-1 in rats. J. Neuroimmunol. 25 (1989) 109-116
32. Persico A.M., and Bourgeron T. Searching for ways out of the autism maze: genetic, epigenetic and environmental clues. Trends Neurosci. 29 (2006) 349-358
33. Plagge A., Isles A.R., Gordon E., Humby T., Dean W., Gritsch S., Fischer-Colbrie R., Wilkinson L.S., and Kelsey G. Imprinted Nesp55 influences behavioral reactivity to novel environments. Mol. Cell. Biol. 25 (2005) 3019-3026
34. Schanen N.C. Epigenetics of autism spectrum disorders. Hum. Mol. Genet. 15 Spec No 2 (2006) R138-150
35. Sebat J., Lakshmi B., Malhotra D., Troge J., Lese-Martin C., Walsh T., Yamrom B., Yoon S., Krasnitz A., Kendall J., Leotta A., Pai D., Zhang R., Lee Y.H., Hicks J., Spence S.J., Lee A.T., Puura K., Lehtimaki T., Ledbetter D., Gregersen P.K., Bregman J., Sutcliffe J.S., Jobanputra V., Chung W., Warburton D., King M.C., Skuse D., Geschwind D.H., Gilliam T.C., Ye K., and Wigler M. Strong association of de novo copy number mutations with autism. Science 316 (2007) 445-449
36. Sridharan D., Levitin D.J., and Menon V. A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 12569-12574
37. Steininger T.L., Gong H., McGinty D., and Szymusiak R. Subregional organization of preoptic area/anterior hypothalamic projections to arousal-related monoaminergic cell groups. J. Comp. Neurol. 429 (2001) 638-653
38. Van Bockstaele E.J., Bajic D., Proudfit H., and Valentino R.J. Topographic architecture of stress-related pathways targeting the noradrenergic locus coeruleus. Physiol. Behav. 73 (2001) 273-283
39. Viemari J.C., Roux J.C., Tryba A.K., Saywell V., Burnet H., Pena F., Zanella S., Bevengut M., Barthelemy-Requin M., Herzing L.B., Moncla A., Mancini J., Ramirez J.M., Villard L., and Hilaire G. Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice. J. Neurosci. 25 (2005) 11521-11530