Biochemical evidence of translational infidelity and decreased peptidyltransferase activity by a sarcin/ricin domain mutation of yeast 25S rRNA

Nucleic Acids Research

Volumn 32, Issue 18, 2004, Pages 5398-5408

  Panopoulos, Panagiotis ^a   Dresios, John ^a,b   Synetos, Dennis ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; ELONGATION FACTOR 2; PAROMOMYCIN; PEPTIDYLTRANSFERASE; RIBOSOME PROTEIN; RIBOSOME RNA; RICIN; RNA 25S; S12 PROTEIN; S23 PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SARCIN; TRANSFER RNA; UNCLASSIFIED DRUG; URACIL; ALPHA SARCIN; ALPHA-SARCIN; ANTIINFECTIVE AGENT; FUNGAL PROTEIN; PEPTIDE; POLYPHENYLALANINE; PROTEIN SYNTHESIS INHIBITOR; RIBONUCLEASE; RNA, RIBOSOMAL, 25S;

ACCURACY; ANALYTICAL ERROR; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOCHEMISTRY; CALCULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EUKARYOTE; FREQUENCY ANALYSIS; GENETIC CONSERVATION; IN VITRO STUDY; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RIBOSOME; RNA TRANSLATION; RNA TRANSPORT; SACCHAROMYCES CEREVISIAE; WILD TYPE; CELL DIVISION; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MUTATION; POLYSOME; PROTEIN SYNTHESIS;

ESCHERICHIA COLI; EUKARYOTA;

ANTI-BACTERIAL AGENTS; CELL DIVISION; DRUG RESISTANCE, FUNGAL; ENDORIBONUCLEASES; FUNGAL PROTEINS; MUTATION; PAROMOMYCIN; PEPTIDES; PEPTIDYL TRANSFERASES; POLYRIBOSOMES; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMAL PROTEINS; RIBOSOMES; RICIN; RNA, RIBOSOMAL; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE;

EID: 6044278241     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh860     Document Type: Article

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