HMMC-1: A humanized monoclonal antibody with therapeutic potential against müllerian duct-related carcinomas

Clinical Cancer Research

Volumn 10, Issue 20, 2004, Pages 7071-7078

  Nozawa, Shiro ^a   Aoki, Daisuke ^a   Tsukazaki, Katsumi ^a   Susumu, Nobuyuki ^a   Sakayori, Motoko ^a   Suzuki, Nao ^a   Suzuki, Atsushi ^a   Wakita, Rie ^a   Mukai, Makio ^a   Egami, Yuko ^b   Kojima Aikawa, Kyoko ^b   Ishida, Isao ^c   Belot, Frederic ^d   Hindsgaul, Ole ^d   Fukuda, Minoru ^d   Fukuda, Michiko N ^d  

^a KEIO UNIVERSITY   (Japan)

^b OCHANOMIZU UNIVERSITY   (Japan)

^c KIRIN BREWERY CO LTD   (Japan)

^d BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GLYCOSYLTRANSFERASE; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY HMMC 1; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; ENDOMETRIUM CANCER; ENDOMETRIUM CARCINOMA; GALLBLADDER; GYNECOLOGIC CANCER; HYBRIDOMA; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; MUELLERIAN DUCT; MUELLERIAN DUCT RELATED CARCINOMA; MYELOMA CELL; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; SPLEEN CELL; UTERINE CERVIX;

ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOMA; DNA, COMPLEMENTARY; FEMALE; GENITAL NEOPLASMS, FEMALE; GLYCOSYLTRANSFERASES; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN M; IMMUNOHISTOCHEMISTRY; MICE; MULLERIAN DUCTS; MULTIPLE MYELOMA; SPLEEN; TUMOR CELLS, CULTURED;

EID: 6044234744     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-0802     Document Type: Article

References (29)

1. Hakomori S. Aberrant glycosylation in cancer cell membranes a sfocused on glycolipids: overview and perspectives. Cancer Res 1985; 45:2405-14.
2. Kannagi R. Monoclonal anti-glycolipid antibodies. Method Enzymol 2000;312:160-79.
3. Nakamori S, Kameyama M, Imaoka S, et al. Increased expression of sialyl LewisX antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res 1993;53:3632-7.
4. Kannagi R, Fukushi Y, Tachikawa T, et al. Quantitative and qualitative characterization of human cancer-associated serum glycoprotein antigens expressing fucosyl or sialyl-fucosyl type 2 chain polylactosamine. Cancer Res 1986;46:2619-26.
5. Poropatich C, Nozawa S, Rojas M, Chapman WB, Silverberg SG. MSN-1 antibody in the evaluation of female genital tract adenocarcinomas. Int J Gynecol Pathol 1990;9:73-9.
6. Nozawa S, Narisawa S, Kojima K, et al. Human monoclonal antibody (HMST-1) against lacto-series type 1 chain and expression of the chain in uterine endometrial cancers. Cancer Res 1989;49:6401-6.
7. Tokuda Y. Antibodies as molecular target-based therapy: trastuzumab. Int J Clin Oncol 2003;8:224-9.
8. Wannesson L, Ghielmini M. Overview of antibody therapy in B-cell non-Hodgkin's lymphoma. Clin Lymphoma 2003;4 Suppl 1:S5-12.
9. Tomizuka K, Shinohara T, Yoshida H, et al. Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies. Proc Natl Acad Sci USA 2000;97:722-7.
10. Tomizuka K, Yoshida H, Uejima H, et al. Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat Genet 1997;16:133-43.
11. Ishida I, Tomizuka K, Yoshida H, et al. Production of human monoclonal and polyclonal antibodies in TransChromo animals. Cloning Stem Cells 2002;4:91-102.
12. Nozawa S, Sakayori M, Ohta K, et al. A monoclonal antibody (MSN-1) against a newly established uterine endometrial cancer cell line (SNG-II) and its application to immunohistochemistry and flow cytometry. Am J Obstet Gynecol 1989;161:1079-86.
13. Iwamori M, Sakayori M, Nozawa S, et al. Monoclonal antibody-defined antigen of human uterine endometrial carcinomas is Leb. J Biochem (Tokyo) 1989;105:718-22.
14. Nozawa S, Udagawa Y, Ohta H, Kurihara S, Fishman WH. Newly established uterine cervical cancer cell line (SKG-III) with Regan isoenzyme, human chorionic gonadotropin beta-subunit, and pregnancy-specific beta 1-glycoprotein phenotypes. Cancer Res 1983;43:1748-60.
15. Susumu N, Kawakami H, Aoki D, Hirano H, Nozawa S. Subcellular localization of blood group Leb carbohydrate antigen (MSN-1-reactive antigen) in endometrial cancer cells. Cancer Res 1993;53:3643-8.
16. Kuan SF, Byrd JC, Basbaum C, Kim YS. Inhibition of mucin glycosylation by aryl-N-acetyl-alpha-galactosaminides in human colon cancer cells. J Biol Chem 1989;264:19271-7.
17. Kukowska-Latallo JF, Larsen RD, Nair RP, Lowe JB. A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha (1,3/1,4)fucosyltransferase. Genes Dev 1990;4:1288-303.
18. Iwai T, Inaba N, Naundorf A, et al. Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N- acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. J Biol Chem 2002;277: 12802-9.
19. Bierhuizen MFA, Mattei M-G, Fukuda M. Expression of the developmental I antigen by a cloned human cDNA encoding a member of a beta-1,6-N- acetylglucodsaminyltransferase gene family. Genes Dev 1993;7:468-78.
20. Yeh JC, Ong E, Fukuda M. Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches. J Biol Chem 1999:274:3215-21.
21. Yeh JC, Hiraoka N, Petryniak B, et al. Novel sulfated lymphocyte homing receptors and their control by a corel extension beta 1,3-N- acetylglucosaminyltransferase. Cell 2001;105:957-69.
22. Larsen RD, Ernst LK, Nair RP, Lowe JB. Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L- fucosyltransferase cDNA that can form the H blood group antigen. Proc Natl Acad Sci USA 1990;87:6674-8.
23. Isshiki S, Togayachi A, Kudo T, et al. Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom. J Biol Chem 1999;274:12499-507.
24. Akama TO, Nakagawa H, Sugihara K, et al. Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science 2002;295:124-7.
25. Hirano T, Takasaki S, Hedrick JL, Wardrip NJ, Amano J, Kobata A. O-linked neutral sugar chains of porcine zona pellucida glycoproteins. Eur J Biochem 1993;214:763-9.
26. Hokke CH, Damm JB, Penninkhof B, Aitken RJ, Kamerling JP, Vliegenthart JF. Structure of the O-linked carbohydrate chains of porcine zona pellucida glycoproteins. Eur J Biochem 1994;221:491-512.
27. Capon C, Wieruszeski JM, Lemoine J, Byrd JC, Leffler H, Kim YS. Sulfated lewis X determinants as a major structural motif in glycans from LS174T-HM7 human colon carcinoma mucin. J Biol Chem 1997; 272:31957-68.
28. Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001:344:783-92.
29. Kawashima I, Yoshida Y, Taya C, et al. Expansion of natural killer cells in mice transgenic for IgM antibody to ganglioside GD2: demonstration of prolonged survival after challenge with syngeneic tumor cells. Int J Oncol 2003;23:381-8.