Non-invasive imaging of beta cell mass: A quantitative analysis

Diabetes Technology and Therapeutics

Volumn 6, Issue 5, 2004, Pages 652-659

  Sweet, Ian R ^a   Cook, Daniel L ^a   Lernmark, Åke ^a   Greenbaum, Carla J ^b   Krohn, Kenneth A ^c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c BENAROYA RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CALCULATION; CELL COMPARTMENTALIZATION; CELL VIABILITY; DIAGNOSTIC IMAGING; HUMAN; HUMAN CELL; IMAGING SYSTEM; INNER CELL MASS; INSULIN DEPENDENT DIABETES MELLITUS; LANGERHANS CELL; LIGAND BINDING; PANCREAS ISLET BETA CELL; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCREENING;

DIABETES MELLITUS, TYPE 1; HUMANS; ISLETS OF LANGERHANS; PANCREAS; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 6044234743     PISSN: 15209156     EISSN: None     Source Type: Journal    
DOI: 10.1089/dia.2004.6.652     Document Type: Article

References (20)

1. Moore A, Bonner-Weir S, Weissleder R: Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes. Diabetes 2001;50:2231-2236.
2. Garnuszek P, Licinska I, Fiedor P, Mazurek AP: The synthesis, radioiodination and preliminary biological study of the new carboxylic derivatives of dithizone. Appl Radiat Isot 1998;49:1563-1571.
3. 18F] fluoroethoxy)benzenesulfonyl)-3-butyl urea: a potential beta-cell imaging agent. J Label Compd Radiopharm 2002;45:763-774.
4. Malaisse WJ: On the track to the beta-cell. Diabetologia 2001;44:393-406.
5. Sweet IR, Cook DL, Lernmark A, Greenbaum CJ, Wallen AR, Marcum ES, Stekhova SA, Krohn KA: Systematic screening of potential beta-cell imaging agents. Biochem Biophys Res Commun 2004;314:976-983.
6. Bailey D, Townsend D, Valk P, Maisey M: Positron Emission Tomography: Principles and Practice. London: Springer Verlag, 2003.
7. Chatham JC, Blackband SJ: Nuclear magnetic resonance spectroscopy and imaging in animal research. ILAR J 2001;42:189-208.
8. Krishna MC, Devasahayam N, Cook JA, Subramanian S, Kuppusamy P, Mitchell JB: Electron paramagnetic resonance for small animal imaging applications. ILAR J 2001;42:209-218.
9. Stefan Y, Orci L, Malaisse-Lagae F, Perrelet A, Patel Y, Unger RH: Quantitation of endocrine cell content in the pancreas of nondiabetic and diabetic humans. Diabetes 1982;31:694-700.
10. Weir GC, Bonner-Weir S, Leahy JL: Islet mass and function in diabetes and transplantation. Diabetes 1990;39:401-405.
11. Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC: Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003;52:102-110.
12. Yoon KH, Ko SH, Cho JH, Lee JM, Ahn YB, Song KH, Yoo SJ, Kang MI, Cha BY, Lee KW, Son HY, Kang SK, Kim HS, Lee IK, Bonner-Weir S: Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 2003;88:2300-2308.
13. 18F]-2-fluoro- 2-deoxy-D-glucose method in resting, healthy human subjects. Eur J Nucl Med 1990;16:267-273.
14. Matschinsky FM, Pagliara AS, Stillings SN, Hover BA: Glucose and ATP levels in pancreatic islet tissue of normal and diabetic rats. J Clin Invest 1976;58:1193-1200.
15. + channels. Neuron 1996;16:1011-1017.
16. Hansen WA, Christie MR, Kahn R, Norgaard A, Abel I, Petersen AM, Jorgensen DW, Baekkeskov S, Nielsen JH, Lernmark A, Egeberg J, Richter-Olesen H, Grainger T, Kristensen JK, Brynitz S, Bilde T: Supravital dithizone staining in the isolation of human and rat pancreatic islets. Diabetes Res 1989;10:53-57.
17. 2 and Fab after intravenous administration in the rat. J Pharm Pharmacol 1997;49:277-281.
18. + channels in pancreatic beta-cells. Spare-channel hypothesis. Diabetes 1988;37:495-498.
19. Gaines KL, Hamilton S, Boyd AE 3rd: Characterization of the sulfonylurea receptor on beta cell membranes. J Biol Chem 1988;263:2589-2592.
20. Olsen KM, Kearns GL, Kemp SF: Glyburide protein binding and the effect of albumin glycation in children, young adults, and older adults with diabetes. J Clin Pharmacol 1995;35:739-745.