Effects of haemofiltration and mannitol treatment on cardiopulmonary-bypass induced immunosuppression

Scandinavian Journal of Immunology

Volumn 69, Issue 3, 2009, Pages 234-241

  Ziegeler, S ^a   Raddatz, A ^a   Schneider, S O ^a   Sandmann, I ^a   Sasse, H ^a   Bauer, I ^a   Kubulus, D ^a   Mathes, A ^a   Lausberg, H F ^a   Rensing, H ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CEFUROXIM INFUS; CEFUROXIME; FENTANYL; FENTANYL CURAMED; FLUNITRAZEPAM; HLA DR ANTIGEN; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MANNITOL; MIDAZOLAM; MIDAZOLAM MALEATE; NORADRENALIN; PANCURONIUM; PANCURONIUM CURAMED; THOMAEMANNIT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ANESTHESIA INDUCTION; ANTIBIOTIC PROPHYLAXIS; ANTIGEN EXPRESSION; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; CELLULAR IMMUNITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ELECTIVE SURGERY; HEART SURGERY; HEMOFILTRATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTOPERATIVE PERIOD; PREMEDICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD14; CARDIOPULMONARY BYPASS; FLOW CYTOMETRY; HEMOFILTRATION; HLA-DR ANTIGENS; HUMANS; INTERLEUKIN-10; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; MANNITOL; MIDDLE AGED; PROSPECTIVE STUDIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 60349129301     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2008.02216.x     Document Type: Article

References (32)

1. Wan S, LeClerc JL, Vincent JL. Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest 1997 112 : 676 92.
2. Grundmann U, Rensing H, Adams HA et al. Endotoxin desensitization of human mononuclear cells after cardiopulmonary bypass: role of humoral factors. Anesthesiology 2000 93 : 359 69.
3. Wilhelm W, Grundmann U, Rensing H et al. Monocyte deactivation in severe human sepsis or following cardiopulmonary bypass. Shock 2002 17 : 354 60.
4. Kleinschmidt S, Wanner GA, Bussmann D et al. Proinflammatory cytokine gene expression in whole blood from patients undergoing coronary artery bypass surgery and its modulation by pentoxifylline. Shock 1998 9 : 12 20.
5. Ziegenfuss T, Wanner GA, Grass C et al. Mixed agonistic-antagonistic cytokine response in whole blood from patients undergoing abdominal aortic aneurysm repair. Intensive Care Med 1999 25 : 279 87.
6. Larsen B, Hoff G, Wilhelm W, Buchinger H, Wanner GA, Bauer M. Effect of intravenous anesthetics on spontaneous and endotoxin-stimulated cytokine response in cultured human whole blood. Anesthesiology 1998 89 : 1218 27.
7. Bauer M, Rensing H, Ziegenfuss T. Anesthesia and perioperative immune function. Anaesthesist 1998 47 : 538 56.
8. Ziegeler S, Raddatz A, Hoff G et al. Antibiotics modulate the stimulated cytokine response to endotoxin in a human ex vivo, in vitro model. Acta Anaesthesiol Scand 2006 50 : 1103 10.
9. Ferreira R, Burgos M, Llesuy S et al. Reduction of reperfusion injury with mannitol cardioplegia. Ann Thorac Surg 1989 48 : 77 83.
10. Fitzgerald DJ, Cecere G. Hemofiltration and inflammatory mediators. Perfusion 2002 17 (Suppl. 23 8.
11. Mojcik CF, Levy JH. Aprotinin and the systemic inflammatory response after cardiopulmonary bypass. Ann Thorac Surg 2001 71 : 745 54.
12. Englberger L, Kipfer B, Berdat PA, Nydegger UE, Carrel TP. Aprotinin in coronary operation with cardiopulmonary bypass: does "low-dose" aprotinin inhibit the inflammatory response? Ann Thorac Surg 2002 73 : 1897 904.
13. Schmartz D, Tabardel Y, Preiser JC et al. Does aprotinin influence the inflammatory response to cardiopulmonary bypass in patients? J Thorac Cardiovasc Surg 2003 125 : 184 90.
14. Wilson BM, Severn A, Rapson NT, Chana J, Hopkins P. A convenient human whole blood culture system for studying the regulation of tumour necrosis factor release by bacterial lipopolysaccharide. J Immunol Methods 1991 139 : 233 40.
15. Bauer I, Wanner GA, Rensing H et al. Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver. Hepatology 1998 27 : 829 38.
16. Frankenberger M, Sternsdorf T, Pechumer H, Pforte H, Ziegler-Heitbrock HW. Differential cytokine expression in human blood monocyte subpopulations: a polymerase chain reaction analysis. Blood 1996 87 : 373 7.
17. Monneret G, Lepape A, Voirin N et al. Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock. Intensive Care Med 2006 32 : 1175 83.
18. Huang H, Yao T, Wang W et al. Continuous ultrafiltration attenuates the pulmonary injury that follows open heart surgery with cardiopulmonary bypass. Ann Thorac Surg 2003 76 : 136 40.
19. Oliver WC Jr., Nuttall GA, Orszulak TA et al. Hemofiltration but not steroids results in earlier tracheal extubation following cardiopulmonary bypass: a prospective, randomized double-blind trial. Anesthesiology 2004 101 : 327 39.
20. Millar AB, Armstrong L, van der Linden J et al. Cytokine production and hemofiltration in children undergoing cardiopulmonary bypass. Ann Thorac Surg 1993 56 : 1499 502.
21. Journois D, Pouard P, Greeley W, Mauriat P, Vouhe P, Sufron D. Hemofiltration during cardiopulmonary bypassin pediatric cardiac surgery. Anesthesiology 1994 81 : 1181 9.
22. Larsen M, Webb G, Kennington S et al. Mannitol in cardioplegia as an oxygen free radical scavenger measured by malondialdehyde. Perfusion 2002 17 : 51 5.
23. Burns KE, Chu MW, Novick RJ et al. Perioperative N-acetylcysteine to prevent renal dysfunction in high-risk patients undergoing cabg surgery: a randomized controlled trial. JAMA 2005 294 : 342 50.
24. Rubens FD, Mesana T. The inflammatory response to cardiopulmonary bypass: a therapeutic overview. Perfusion 2004 19 (Suppl. 1 S5 12.
25. Kilger E, Weis F, Briegel J et al. Stress doses of hydrocortisone reduce severe systemic inflammatory response syndrome and improve early outcome in a risk group of patients after cardiac surgery. Crit Care Med 2003 31 : 1068 74.
26. Weis F, Kilger E, Roozendaal B et al. Stress doses of hydrocortisone reduce chronic stress symptoms and improve health-related quality of life in high-risk patients after cardiac surgery: a randomized study. J Thorac Cardiovasc Surg 2006 131 : 277 82.
27. Verrier ED, Shernan SK, Taylor KM et al. Terminal complement blockade with pexelizumab during coronary artery bypass graft surgery requiring cardiopulmonary bypass: a randomized trial. JAMA 2004 291 : 2319 27.
28. Alexiou C, Tang AA, Sheppard SV et al. The effect of leucodepletion on leucocyte activation, pulmonary inflammation and respiratory index in surgery for coronary revascularisation: a prospective randomised study. Eur J Cardiothorac Surg 2004 26 : 294 300.
29. Tang AT, Alexiou C, Hsu J, Sheppard SV, Haw MP, Ohri SK. Leukodepletion reduces renal injury in coronary revascularization: a prospective randomized study. Ann Thorac Surg 2002 74 : 372 7.
30. Echtenacher B, Falk W, Mannel DN, Krammer PH. Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. J Immunol 1990 145 : 3762 6.
31. Tracey KJ, Fong Y, Hesse DG et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 1987 330 : 662 4.
32. Levin M, Quint PA, Goldstein B et al. Recombinant bactericidal/ permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group. Lancet 2000 356 : 961 7.