Long-term evaluation of a calcium phosphate bone cement with carboxymethyl cellulose in a vertebral defect model

Journal of Biomedical Materials Research - Part A

Volumn 88, Issue 4, 2009, Pages 880-888

  Kobayashi, Hideo ^a   Fujishiro, Takaaki ^a   Belkoff, Stephen M ^b   Kobayashi, Naomi ^a   Turner, A Simon ^c   Seim III, Howard B ^c   Zitelli, Joseph ^d   Hawkins, Monica ^d   Bauer, Thomas W ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Department of Ecosystem Science and Sustainability   (United States)

^d STRYKER ORTHOPAEDICS   (United States)

Author keywords

Calcium phosphate cement; Histology; Mechanical properties; Spinal surgery; Vertebral augmentation

Indexed keywords

BONE FORMATIONS; BONE INGROWTHS; BONE MARROWS; CALCIUM PHOSPHATE BONE CEMENTS; CALCIUM PHOSPHATE CEMENT; CARBOXY METHYL CELLULOSE; COMPRESSIVE PROPERTIES; COMPRESSIVE TESTING; DEFECT MODELS; EMPTY SPACES; FIBROUS TISSUES; HISTOMORPHOMETRY; LONG-TERM EVALUATIONS; NEW JERSEYS; OSTEOCONDUCTIVITY; SPINAL SURGERY; STRYKER; VERTEBRAL AUGMENTATION; VERTEBRAL BODIES; VERTEBRAL BONES; VOID MODELS;

AGRICULTURAL PRODUCTS; ANIMALS; BIOCOMPATIBILITY; BIOLOGICAL RADIATION EFFECTS; BIOMECHANICS; BONE; CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; CELLULOSE; CELLULOSE DERIVATIVES; CEMENTS; COMPRESSIVE STRENGTH; DEFECTS; HISTOLOGY; MECHANICAL PROPERTIES; MECHANICAL TESTING; ORTHOPEDICS; PHOSPHATES; POLYMETHYL METHACRYLATES; STRENGTH OF MATERIALS; SURGERY; WOOL;

BONE CEMENT;

BONE CEMENT; CALCIUM PHOSPHATE; CARBOXYMETHYLCELLULOSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BONE CONDUCTION; BONE GROWTH; BONE MARROW; COMPRESSIVE STRENGTH; CONTROLLED STUDY; EVALUATION; HISTOLOGY; LUMBAR SPINE; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOTOMY; POSTOPERATIVE PERIOD; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SHEEP; SPINE RADIOGRAPHY; SPINE SURGERY; TIME; VERTEBRA; VERTEBRA BODY; VERTEBRA MALFORMATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE CEMENTS; BONE REGENERATION; CALCIFICATION, PHYSIOLOGIC; CARBOXYMETHYLCELLULOSE; COMPRESSIVE STRENGTH; ELASTICITY; FEMALE; HUMANS; LUMBAR VERTEBRAE; MATERIALS TESTING; RANDOM ALLOCATION; SHEEP, DOMESTIC; TENSILE STRENGTH;

ALLOY; ANIMALS; CALCIUM; CALCIUM PHOSPHATE; CELLULOSE; CELLULOSE DERIVATIVES; CEMENT; DEFECTS; MECHANICAL PROPERTIES; MECHANICAL TESTS; PHOSPHATES; POLYMETHYL METHACRYLATE; WOOL;

EID: 60349112497     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31933     Document Type: Article

References (43)

1. Lieberman I, Reinhardt MK. Vertebroplasty and kyphoplasty for osteolytic vertebral collapse. Clin Orthop Relat Res 2003: S176-S186.
2. Cotten A, Dewatre F, Cortet B, Assaker R, Leblond D, Duquesnoy B, Chastanet P, Clarisse J. Percutaneous vertebroplasty for osteolytic metastases and myeloma: Effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up. Radiology 1996;200:525-530.
3. Mathis JM, Barr JD, Belkoff SM, Barr MS, Jensen ME, Deramond H. Percutaneous vertebroplasty: A developing standard of care for vertebral compression fractures. AJNR Am J Neuroradiol 2001;22:373-81.
4. Heini PF, Berlemann U. Bone substitutes in vertebroplasty. Eur Spine J 2001;10 (Suppl 2):S205-S213.
5. Togawa D, Kovacic JJ, Bauer TW, Reinhardt MK, Brodke DS, Lieberman IH. Radiographic and histologic findings of vertebral augmentation using polymethylmethacrylate in the primate spine: Percutaneous vertebroplasty versus kyphoplasty. Spine 2006;31:E4-E10.
6. Belkoff SM, Molloy S. Temperature measurement during polymerization of polymethylmethacrylate cement used for vertebroplasty. Spine 2003;28:1555-1559.
7. Deramond H, Wright NT, Belkoff SM. Temperature elevation caused by bone cement polymerization during vertebroplasty. Bone 1999;25:17S-21S.
8. Deramond H, Depriester C, Galibert P, Le Gars D. Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results. Radiol Clin North Am 1998;36:533-546.
9. Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: Technical aspects. AJNR Am J Neuroradiol 1997;18:1897-1904.
10. Wenger M, Markwalder TM. Surgically controlled, transpedicular methyl methacrylate vertebroplasty with fluoroscopic guidance. Acta Neurochir (Wien) 1999;141:625-631.
11. Heini PF, Berlemann U, Kaufmann M, Lippuner K, Fankhauser C, van Landuyt P. Augmentation of mechanical properties in osteoporotic vertebral bones - A biomechanical investigation of vertebroplasty efficacy with different bone cements. Eur Spine J 2001;10:164-171.
12. Bai B, Jazrawi LM, Kummer FJ, Spivak JM. The use of an injectable, biodegradable calcium phosphate bone substitute for the prophylactic augmentation of osteoporotic vertebrae and the management of vertebral compression fractures. Spine 1999;24:1521-1526.
13. Lim TH, Brebach GT, Renner SM, Kim WJ, Kim JG, Lee RE, Andersson GB, An HS. Biomechanical evaluation of an injectable calcium phosphate cement for vertebroplasty. Spine 2002;27:1297-1302.
14. Bai B, Kummer FJ, Spivak J. Augmentation of anterior vertebral body screw fixation by an injectable, biodegradable calcium phosphate bone substitute. Spine 2001;26:2679-2683.
15. Verlaan JJ, van Helden WH, Oner FC, Verbout AJ, Dhert WJ. Balloon vertebroplasty with calcium phosphate cement augmentation for direct restoration of traumatic thoracolumbar vertebral fractures. Spine 2002;27:543-548.
16. Frankenburg EP, Goldstein SA, Bauer TW, Harris SA, Poser RD. Biomechanical and histological evaluation of a calcium phosphate cement. J Bone Joint Surg Am 1998;80:1112-1124.
17. Brown WE, Chow LC. A new calcium phosphate, water-setting cement. Cem Res Prog 1986:352-379.
18. Cherng A, Takagi S, Chow LC. Effects of hydroxypropyl methylcellulose and other gelling agents on the handling properties of calcium phosphate cement. J Biomed Mater Res 1997;35:273-277.
19. Chow LC, Markovic M, Takagi S, Cherng M. Injectable calcium phosphate cements. Effect of cement liquid on the physical properties of the cement. Innov Techn Bio Med GRIBOI 1997;18:11-14.
20. Nakano M, Hirano N, Ishihara H, Kawaguchi Y, Watanabe H, Matsuura K. Calcium phosphate cement-based vertebroplasty compared with conservative treatment for osteoporotic compression fractures: A matched case-control study. J Neurosurg Spine 2006;4:110-117.
21. Kobayashi N, Ong K, Villarraga M, Schwardt J, Wenz R, Togawa D, Fujishiro T, Turner AS, Seim HB, III, Bauer TW. Histological and mechanical evaluation of self-setting calcium phosphate cements in a sheep vertebral bone void model. J Biomed Mater Res A 2007;81:838-846.
22. Taniwaki Y, Takemasa R, Tani T, Mizobuchi H, Yamamoto H. Enhancement of pedicle screw stability using calcium phosphate cement in osteoporotic vertebrae: In vivo biomechanical study. J Orthop Sci 2003;8:408-414.
23. Rodgers JB, Vasconez HC, Wells MD, DeLuca PP, Faugere MC, Fink BF, Hamilton D. Two lyophilized polymer matrix recombinant human bone morphogenetic protein-2 carriers in rabbit calvarial defects. J Craniofac Surg 1998;9:147-153.
24. Aspenberg P, Lohmander LS. Fibroblast growth factor stimulates bone formation. Bone induction studied in rats. Acta Orthop Scand 1989;60:473-476.
25. Ambard AJ, Mueninghoff L. Calcium phosphate cement: Review of mechanical and biological properties. J Prosthodont 2006;15:321-328.
26. Friedman CD, Costantino PD, Takagi S, Chow LC. BoneSource hydroxyapatite cement: A novel biomaterial for craniofacial skeletal tissue engineering and reconstruction. J Biomed Mater Res 1998;43:428-432.
27. Ishikawa K, Asaoka K. Estimation of ideal mechanical strength and critical porosity of calcium phosphate cement. J Biomed Mater Res 1995;29:1537-1543.
28. Stankewich CJ, Swiontkowski MF, Tencer AF, Yetkinler DN, Poser RD. Augmentation of femoral neck fracture fixation with an injectable calcium-phosphate bone mineral cement. J Orthop Res 1996;14:786-793.
29. Van Heest A, Swiontkowski M. Bone-graft substitutes. Lancet 1999;353(Suppl 1):SI28-SI29.
30. Cassidy C, Jupiter JB, Cohen M, Delli-Santi M, Fennell C, Leinberry C, Husband J, Ladd A, Seitz WR, Constanz B. Norian SRS cement compared with conventional fixation in distal radial fractures. A randomized study. J Bone Joint Surg Am 2003;85-A:2127-2137.
31. Goodman SB, Bauer TW, Carter D, Casteleyn PP, Goldstein SA, Kyle RF, Larsson S, Stankewich CJ, Swiontkowski MF, Tencer AF, Yetkinler DN, Poser RD. Norian SRS cement augmentation in hip fracture treatment. Laboratory and initial clinical results. Clin Orthop Relat Res 1998:42-50.
32. Lieberman IH, Togawa D, Kayanja MM. Vertebroplasty and kyphoplasty: Filler materials. Spine J 2005;5:305S-316S.
33. Verlaan JJ, Oner FC, Slootweg PJ, Verbout AJ, Dhert WJ. Histologic changes after vertebroplasty. J Bone Joint Surg Am 2004;86-A:1230-1238.
34. Libicher M, Hillmeier J, Liegibel U, Sommer U, Pyerin W, Vetter M, Meinzer HP, Grafe I, Meeder P, Noldge G, Nawroth P, Kasperk C. Osseous integration of calcium phosphate in osteoporotic vertebral fractures after kyphoplasty: Initial results from a clinical and experimental pilot study. Osteoporos Int 2006;17:1208-1215.
35. Mattsson P, Alberts A, Dahlberg G, Sohlman M, Hyldahl HC, Larsson S. Resorbable cement for the augmentation of internally-fixed unstable trochanteric fractures. A prospective, randomised multicentre study. J Bone Joint Surg Br 2005;87:1203-1209.
36. Dickson KF, Friedman J, Buchholz JG, Flandry FD. The use of BoneSource hydroxyapatite cement for traumatic metaphyseal bone void filling. J Trauma 2002;53:1103-1108.
37. Aerssens J, Boonen S, Lowet G, Dequeker J. Interspecies differences in bone composition, density, and quality: Potential implications for in vivo bone research. Endocrinology 1998;139:663-670.
38. Hartke JR. Preclinical development of agents for the treatment of osteoporosis. Toxicol Pathol 1999;27:143-147.
39. Belkoff SM, Mathis JM, Deramond H, Jasper LE. An ex vivo biomechanical evaluation of a hydroxyapatite cement for use with kyphoplasty. AJNR Am J Neuroradiol 2001;22:1212-1216.
40. Belkoff SM, Mathis JM, Jasper LE, Deramond H. An ex vivo biomechanical evaluation of a hydroxyapatite cement for use with vertebroplasty. Spine 2001;26:1542-1546.
41. Kobayashi N, Togawa D, Fujishiro T, Powell KA, Turner AS, Seim HB III, Bauer TW. Histological and radiographic evaluation of polymethylmethacrylate with two different concentrations of barium sulfate in a sheep vertebroplasty model. J Biomed Mater Res A 2005;75:123-127.
42. Aebli N, Krebs J, Schwenke D, Davis G, Theis JC. Cardiovascular changes during multiple vertebroplasty with and without vent-hole: An experimental study in sheep. Spine 2003;28:1504-1511. Discussion 11-12.
43. Aebli N, Goss BG, Thorpe P, Williams R, Krebs J. In vivo temperature profile of intervertebral discs and vertebral endplates during vertebroplasty: An experimental study in sheep. Spine 2006;31:1674-1678. Discussion 9.