Synthesis and evaluation of ligands for D2-like receptors: The role of common pharmacophoric groups

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 4, 2009, Pages 1716-1723

  Sikazwe, Donald M N ^a   Nkansah, Nancy T ^a   Altundas, Ramazan ^a   Zhu, Xue Y ^a   Roth, Bryan L ^b   Setola, Vincent ^b   Ablordeppey, Seth Y ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Antipsychotics; Bicyclic analogs; Butyrophenone; D2 like receptor ligands; Diazepane; Dopamine receptor ligands; Haloperidol analog

Indexed keywords

BUTYROPHENONE DERIVATIVE; CLOZAPINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; INDOLE DERIVATIVE;

ARTICLE; DRUG ACCUMULATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; PHARMACOPHORE; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANTIPSYCHOTIC AGENTS; BINDING SITES; BUTYROPHENONES; HALOPERIDOL; HUMANS; INDOLES; KINETICS; LIGANDS; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 60249103815     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.12.054     Document Type: Article

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