Painful tonic heat stimulation induces GABA accumulation in the prefrontal cortex in man

Pain

Volumn 142, Issue 1-2, 2009, Pages 89-93

  Kupers, Ron ^a,b   Danielsen, Else R ^a   Kehlet, Henrik ^a   Christensen, Rune ^b   Thomsen, Carsten ^a,c  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Anterior cingulate cortex; Brain imaging; GABA; H MRS; Pain

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID;

ADULT; ARTICLE; CINGULATE GYRUS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEAT; HUMAN; MALE; NOCICEPTIVE STIMULATION; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; PAIN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTON NUCLEAR MAGNETIC RESONANCE;

ADULT; BRAIN MAPPING; FEMALE; GAMMA-AMINOBUTYRIC ACID; HOT TEMPERATURE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; OXYGEN; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PREFRONTAL CORTEX; YOUNG ADULT;

EID: 60249096638     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2008.12.008     Document Type: Article

References (39)

1. An X., Bandler R., Ongür D., and Price J.L. Prefrontal cortical projections to longitudinal columns in the midbrain periaqueductal gray in macaque monkeys. J Comp Neurol 401 (1998) 455-479
2. Baliki M.N., Chialvo D.R., Geha P.Y., Levy R.M., Harden R.N., Parrish T.B., et al. Chronic pain and the emotional brain: specific brain activity associated with spontaneous fluctuations of intensity of chronic back pain. J Neurosci 26 (2006) 12165-12173
3. Ballantine Jr. H.T., Cassidy W.L., Flanagan N.B., and Marino Jr. R. Stereotaxic anterior cingulotomy for neuropsychiatric illness and intractable pain. J Neurosurg 26 (1967) 488-495
4. Bozkurt A., Zilles K., Schleicher A., Kamper L., Arigita E.S., Uylings H.B., et al. Distributions of transmitter receptors in the macaque cingulate cortex. Neuroimage 25 (2005) 219-229
5. Büchel C., Bornhovd K., Quante M., Glauche V., Bromm B., and Weiller C. Dissociable neural responses related to pain intensity, stimulus intensity, and stimulus awareness within the anterior cingulate cortex: a parametric single-trial laser functional magnetic resonance imaging study. J Neurosci 22 (2002) 970-976
6. Bush G., Luu P., and Posner M.I. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4 (2000) 215-222
7. Carmichael S.T., and Price J.L. Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys. J Comp Neurol 363 (1995) 615-641
8. Casey K.L., Svensson P., Morrow T.J., Raz J., Jone C., and Minoshima S. Selective opiate modulation of nociceptive processing in the human brain. J Neurophysiol 84 (2000) 525-533
9. Chiou L.C., and Huang L.Y. Mechanism underlying increased neuronal activity in the rat ventrolateral periaqueductal grey by a mu-opioid. J Physiol 518 (2000) 551-559
10. Chu D.C., Albin R.L., Young A.B., and Penney J.B. Distribution and kinetics of GABAB binding sites in rat central nervous system: a quantitative autoradiographic study. Neuroscience 34 (1990) 341-357
11. Davis K.D., Taub E., Duffner F., Lozano A.M., Tasker R.R., Houle S., et al. Activation of the anterior cingulate cortex by thalamic stimulation in patients with chronic pain: a positron emission tomography study. J Neurosurg 92 (2000) 64-69
12. deCharms R.C., Maeda F., Glover G.H., Ludlow D., Pauly J.M., Soneji D., et al. Control over brain activation and pain learned by using real-time functional MRI. Proc Natl Acad Sci USA 102 (2005) 18626-18631
13. Enna S.J., and McCarson K.E. The role of GABA in the mediation and perception of pain. Adv Pharmacol 54 (2006) 1-27
14. Ethofer T., Seeger U., Klose U., Erb M., Kardatzki B., Kraft E., et al. Proton MR spectroscopy in succinic semialdehyde dehydrogenase deficiency. Neurology 62 (2004) 1016-1018
15. Faymonville M.E., Roediger L., Del Fiore G., Delgueldre C., Phillips C., Lamy M., et al. Increased cerebral functional connectivity underlying the antinociceptive effects of hypnosis. Brain Res Cogn Brain Res 17 (2003) 255-262
16. Fritschy J.M., and Mohler H. GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. J Comp Neurol 359 (1995) 154-194
17. Fuchs P.N., Balinsky M., and Melzack R. Electrical stimulation of the cingulum bundle and surrounding cortical tissue reduces formalin-test pain in the rat. Brain Res 743 (1996) 116-123
18. Gigg J., Tan A.M., and Finch D.M. Glutamatergic excitatory responses of anterior cingulate neurons to stimulation of the mediodorsal thalamus and their regulation by GABA: an in vivo iontophoretic study. Cereb Cortex 2 (1992) 477-484
19. 1H NMR measurements of 2-pyrrolidinone in human brain in vivo. Magn Reson Med 41 (1999) 889-896
20. Ipponi A., Lamberti C., Medica A., Bartolini A., and Malmberg-Aiello P. Tiagabine antinociception in rodents depends on GABA(B) receptor activation: parallel antinociception testing and medial thalamus GABA microdialysis. Eur J Pharmacol 368 (1999) 205-211
21. Jasmin L., Rabkin S.D., Granato A., Boudah A., and Ohama P.T. Analgesia and hyperalgesia from GABA mediated modulation of the cerebral cortex. Nature 424 (2003) 316-320
22. Jasmin L., Wu M.V., and Ohara P.T. GABA puts a stop to pain. Curr Drug Targets CNS Neurol Disord 3 (2004) 487-505
23. Johansen J.P., Fields H.L., and Manning B.H. The affective component of pain in rodents: direct evidence for a contribution of the anterior cingulate cortex. Proc Natl Acad Sci USA 98 (2001) 8077-8082
24. Kulkarni B., Bentley D.E., Elliott R., Julyan P.J., Boger E., Watson A., et al. Arthritic pain is processed in brain areas concerned with emotions and fear. Arthritis Rheum 56 (2007) 1345-1354
25. Kulkarni B., Bentley D.E., Elliott R., Youell P., Watson A., Derbyshire S.W., et al. Attention to pain localization and unpleasantness discriminates the functions of the medial and lateral pain systems. Eur J Neurosci 21 (2005) 3133-3142
26. Kupers R., and Kehlet H. Brain imaging of clinical pain states: a critical review and strategies for future studies. Lancet Neurol 5 (2006) 1033-1044
27. LaGraize S.C., Borzan J., Peng Y.B., and Fuchs P.N. Selective regulation of pain affect following activation of the opioid anterior cingulate cortex system. Exp Neurol 197 (2006) 22-30
28. LaGraize S., and Fuchs P.N. GABAA but not GABAB receptors in the rostral anterior cingulate cortex selectively modulate pain-induced escape/avoidance behavior. Exp Neurol 204 (2007) 182-194
29. Mullins P.G., Rowland L.M., Jung R.E., and Sibbitt Jr. W.L. A novel technique to study the brain's response to pain: proton magnetic resonance spectroscopy. Neuroimage 26 (2005) 642-646
30. Naert A.L., Kehlet H., and Kupers R. Characterization of a novel model of tonic heat pain stimulation in healthy volunteers. Pain 138 (2008) 163-171
31. Petrovic P., Kalso E., Petersson K.M., and Ingvar M. Placebo and opioid analgesia - imaging a shared neuronal network. Science 295 (2002) 1737-1740
32. Peyron R., Faillenot I., Mertens P., Laurent B., and Garcia-Larrea L. Motor cortex stimulation in neuropathic pain. Correlations between analgesic effect and hemodynamic changes in the brain. A PET study. Neuroimage 34 (2007) 310-321
33. Provencher S. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 30 (1993) 672-679
34. Rainville P., Duncan G.H., Price D.D., Carrier B., and Bushnell M.C. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 277 (1997) 968-971
35. Ray J.P., and Price J.L. The organization of projections from the mediodorsal nucleus of the thalamus to orbital and medial prefrontal cortex in macaque monkeys. J Comp Neurol 337 (1993) 1-31
36. 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo. Proc Natl Acad Sci USA 90 (1993) 5662-5666
37. Vogt B.A. Pain and emotion interactions in subregions of the cingulate gyrus. Nat Rev Neurosci 6 (2005) 533-544
38. Vogt B.A., Derbyshire S., and Jones A.K.P. Pain processing in four regions of human cingulate cortex localized with co-registered PET and MR imaging. Eur J Neurosci 8 (1996) 1461-1473
39. Vogt B.A., Vogt L., Farber N.B., and Bush G. Architecture and neurocytology of monkey cingulate gyrus. J Comp Neurol 485 (2005) 218-239