A physiologically based pharmacokinetic model linking plasma protein binding interactions with drug disposition

Research in Veterinary Science

Volumn 86, Issue 2, 2009, Pages 293-301

  Buur, J L ^a   Baynes, R E ^a   Smith, G W ^a   Riviere, J E ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Drug drug interaction; Flunixin meglumine; Physiologically based pharmacokinetic model (PBPK); Plasma protein binding; Sulfamethazine

Indexed keywords

FLUNIXIN MEGLUMINE; SULFADIMIDINE;

ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL MODEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISPOSITION; DRUG INHIBITION; DRUG METABOLISM; DRUG PROTEIN BINDING; FEMALE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PLASMA PROTEIN BINDING; SWINE;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOOD PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONIXIN; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FEMALE; MODELS, BIOLOGICAL; PHARMACOKINETICS; PROTEIN BINDING; SULFAMETHAZINE; SWINE; TISSUE DISTRIBUTION;

SUIDAE;

EID: 60249087465     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2008.07.003     Document Type: Article

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