Carbocation rearrangements in aspernomine biosynthesis

Tetrahedron Letters

Volumn 50, Issue 14, 2009, Pages 1578-1581

  Ho, Gregory A ^a   Nouri, Dustin H ^a   Tantillo, Dean J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPERNOMINE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLOADDITION; QUANTUM CHEMISTRY;

EID: 60249084804     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.01.098     Document Type: Article

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14. 2 bridge with two H's) was also located; the computed barrier (not including entropy) for this [4+2] reaction is 10.72 kcal/mol and it is exothermic by 14.87 kcal/mol. See Supplementary data for details.
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19. A-to-B being less polar than A, but also suggesting that the barrier for this reaction is likely to be low in a variety of environments.