Synthesis, characterization and antidiabetic properties of N1-2,4-dihydroxybenzylidene-N4-2-hydroxybenzylidene-S-methyl-thiosemicarbazidato-oxovanadium(IV)

European Journal of Medicinal Chemistry

Volumn 44, Issue 2, 2009, Pages 818-826

  Yanardag, Refiye ^a   Demirci, Tulay Bal ^a   Ülküseven, Bahri ^a   Bolkent, Sema ^b   Tunali, Sevim ^a   Bolkent, Sehnaz ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Antidiabetic effects on pancreas; Biochemical and immunohistochemical studies; In vivo studies; S Methylthiosemicarbazone oxovanadium; Structural characterization

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; N1 2,4 DIHYDROXYBENZYLIDENE N4 2 HYDROXYBENZYLIDENE S METHYLTHIOSEMICARBAZIDATOOXOVANADIUM; SUPEROXIDE DISMUTASE; THIOSEMICARBAZIDE DERIVATIVE; UNCLASSIFIED DRUG; VANADIUM DERIVATIVE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ACTIVITY; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; INFRARED SPECTROSCOPY; MALE; MASS SPECTROMETRY; NONHUMAN; RAT; STREPTOZOCIN DIABETES; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; MOLECULAR MIMICRY; ORGANOMETALLIC COMPOUNDS; PANCREAS; PROTECTIVE AGENTS; RATS; REGENERATION; SPECTRUM ANALYSIS; TREATMENT OUTCOME; VANADATES;

EID: 60149106421     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.04.023     Document Type: Article

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