Long-term follow-up of 111 patients with persistent polyclonal B-cell lymphocytosis with binucleated lymphocytes

Leukemia

Volumn 23, Issue 2, 2009, Pages 419-422

  Cornet, E ^a   Lesesve, J F ^b   Mossafa, H ^c   Sebahoun G ^d   Levy, V ^e   Davi, F ^f   Troussard, X ^a  

^a CAEN UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY HOSPITAL OF NANCY   (France)

^c LABORATOIRE CERBA   (France)

^d HÔPITAL NORD   (France)

^e SAINT LOUIS HOSPITAL   (France)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; CYTARABINE; DOXORUBICIN; ETOPOSIDE; FLUDARABINE; METHOTREXATE; PREDNISONE; RITUXIMAB; VINDESINE;

ADULT; AGED; B CELL LYMPHOMA; BLOOD SMEAR; CANCER COMBINATION CHEMOTHERAPY; CHROMOSOMAL INSTABILITY; CYTOGENETICS; DIAGNOSTIC PROCEDURE; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GENE AMPLIFICATION; GENE REARRANGEMENT; HUMAN; ISOCHROMOSOME; LARGE CELL LYMPHOMA; LETTER; LYMPHOCYTE COUNT; LYMPHOCYTOSIS; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; NONHODGKIN LYMPHOMA; PERSISTENT POLYCLONAL B CELL LYMPHOCYTOSIS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SMOKING CESSATION; SPLENOMEGALY;

EID: 60149095545     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2008.208     Document Type: Letter

References (11)

1. Gordon DS, Jones BM, Browing SW, Spira TJ, Laurence DN. Persistent polyclonal lymphocytosis of B-lymphocytes. New Engl J Med 1982; 307: 232-236.
2. Mossafa H, Malaure H, Maynadie M, Valensi F, Schillinger F, Garand R, et al., and the Groupe Française d'Hématologie Cellulaire (GFHC). Persistent polyclonal B lymphocytosis with binucleated lymphocytes: A study of 25 cases. Br J Haematol 1999; 104: 486-493.
3. Lawlor E, Murray M, O'Brian DS, Blaney C, Foroni L, Sarsfield P et al. Persistent polyclonal B lymphocytosis with Epstein-Barr virus antibodies and subsequent malignant pulmonary blastoma. J Clin Pathol 1991; 44: 341-342.
4. Roy J, Ryckman C, Bernier V, Whittom R, Delage R. Large cell lymphoma complicating persistent polyclonal B cell lymphocytosis. Leukemia 1998; 12: 1026-1030.
5. Chan MA, Benedict SH, Carstairs KC, Francombe WH, Gelfand EW. Expansion of B-lymphocytes with an unusual immunoglobulin rearrangment associated with atypical lymphocytosis and cigarette smoking. Am J Respir Cell Mol Biol 1990; 2: 549-552.
6. Delage B, Darveau A, Jacques L, Huot A, Delage JM. Chronic B-cell lymphocytosis of the young woman: Clinical, phenotypic, and molecular studies. Blood 1992; 80 (Suppl 1): 447a.
7. Feugier P, Kennel de March A, Lesesve JF, Monhoven N, Dorvaux V, Braun F et al. Intravascular bone marrow accumulation in persistent polyclonal lymphocytosis: A misleading feature for B-cell neoplasm. Mod Pathol 2004; 17: 1087-1096.
8. Troussard X, Valensi F, Debert C, Maynadie M, Schillinger F, Bonnet P et al. Polyclonal lymphocytosis with binucleated lymphocytes: A genetic predisposition. Br J Haematol 1994; 88: 275-280.
9. Mossafa H, Tapia S, Flandrin G, Troussard X and the groupe français d'hématologie cellulaire (GFHC). Chromosomal instability and ATR amplification gene in patients with persistent polyclonal B-cell lymphocytosis (PPBL). Leuk Lymphoma 2004; 45: 1401-1406.
10. Smith L, Liu SJ, Goodrich L, Jacobson D, Degnin C, Bentley N et al. Duplication of ATR inhibits MyoD, induces aneuploidy and eliminates radiation-induced G1 arrest. Nat Genet 1998; 19: 39-46.
11. van Dongen JJ, Langerak AW, Brüggemann M, Evans PA, Hummel M, Lavender FL et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 concerted action BMH4-CT98-3936. Leukemia 2003; 17: 2257-2317.