Intravascular bone marrow accumulation in persistent polyclonal lymphocytosis: A misleading feature for B-cell neoplasm

Modern Pathology

Volumn 17, Issue 9, 2004, Pages 1087-1096

  Feugier, Pierre ^a   De March, Anne Kennel ^a   Lesesve, Jean F ^a   Monhoven, Nathalie ^a   Dorvaux, Véronique ^b   Braun, Françoise ^b   Grégoire, Marie J ^a   Jonveaux, Philippe ^a   Lederlin, Pierre ^a   Béné, Marie C ^a   Labouyrie, Eric ^a,c  

^a UNIVERSITY HOSPITAL OF NANCY   (France)

^b Hospital Metz   (France)

^c CHU NANCY BRABOIS   (France)

Author keywords

Bone marrow; Intravascular; Polyclonal B cell lymphocytosis

Indexed keywords

CELL ADHESION MOLECULE; IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN BCL 2;

ADULT; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL MIGRATION; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CLONE; DIAGNOSTIC ERROR; FEMALE; GENE EXPRESSION; GENE REARRANGEMENT; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEUKEMIA; LYMPHOCYTIC INFILTRATION; LYMPHOCYTOSIS; LYMPHOPROLIFERATIVE DISEASE; MALE; NEOPLASM; NONHODGKIN LYMPHOMA; POLYCLONAL B CELL LYMPHOCYTOSIS; PRECANCER; PRIORITY JOURNAL; SMOKING; SYNDROME;

ADULT; ANTIGENS, CD; B-LYMPHOCYTES; BLOOD VESSELS; BONE MARROW; CYTOGENETIC ANALYSIS; FEMALE; GENE REARRANGEMENT; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOPHENOTYPING; KARYOTYPING; LYMPHOCYTOSIS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA;

EID: 4344709058     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3800156     Document Type: Article

References (36)

1. Hamblin. TJ. Achieving optimal outcomes in chronic lymphocytic leukaemia. Drugs 2001;61:593-611.
2. Wilkinson LS, Tang A, Gjedsted A. Marked lymphocytosis suggesting chronic lymphocytic leukemia in three patients with hyposplenism. Am J Med 1983;75:1053-1056.
3. Berthelot JM, Bataille R, Maugars Y, et al. Rheumatoid arthritis as a bone marrow disorder. Semin Arthritis Rheum 1996;26:505-514.
4. Marti GE, Ryan ET, Papadopoulos NM, et al. Polyclonal B-cell lymphocytosis and hypergammaglobulinemia in patients with Gaucher disease. Am J Hematol 1988;29:189-194.
5. Gordon DS, Jones BM, Browning SW, et al. Persistent polyclonal lymphocytosis of B lymphocytes. N Engl J Med 1982;307:232-236.
6. Troussard X, Valensi F, Debert C, et al. Persistent polyclonal lymphocytosis with binucleated B lymphocytes: a genetic predisposition. Br J Haematol 1994;88:275-280.
7. Carr R, Fishlock K, Matutes E. Persistent polyclonal B-cell lymphocytosis in identical twins. Br J Haematol 1997;96:272-274.
8. Delage R, Jacques L, Massinga-Loembe M, et al. Persistent polyclonal B-cell lymphocytosis: further evidence for a genetic disorder associated with B-cell abnormalities. Br J Haematol 2001;114:666-670.
9. Delage R, Darveau A, Jacques L, et al. Chronic B cell lymphocytosis of the young woman: clinical, phenotypic and molecular studies in 5 cases. Blood 1992;80(Suppl 1):447a (abstract).
10. Chan MA, Benedict SH, Carstairs KC, et al. Expansion of B lymphocytes with an unusual immunoglobulin rearrangement associated with atypical lymphocytosis and cigarette smoking. Am J Respir Cell Mol Biol 1990;2:549-552.
11. Mossafa H, Troussard X, Valensi F, et al. Isochromosome i(3q) and premature chromosome condensation are recurrent findings in chronic B-cell lymphocytosis with binucleate lymphocytes. Leuk Lymphoma 1996;20:267-273.
12. Perreault C, Boileau J, Gyger M, et al. Chronic B-cell lymphocytosis. Eur J Hematol 1989;42:361-367.
13. Kennel-De March A, Béné MC, Renoult E, et al. Low levels of spontaneously activated peripheral IgA-secreting cells in non transplanted IgA nephropathy patients. Am J Kidney Dis 1997;30:64-70.
14. Dean PN, Jett JH. Mathematical analysis of DNA distributions derived from flow microfluorometry. J Cell Biol 1974;60:523-527.
15. Delabie J, Tierens A, Wu G, et al. Lymphocyte predominance Hodgkin's disease: lineage and clonality determination using a single-cell assay. Blood 1994;84:3291-3298.
16. Diss TC, Peng H, Wotherspoon AC, et al. Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J Pathol 1993;169: 291-295.
17. McCarthy KP, Sloane JP, Kabarowski JH, et al. A simplified method for the detection of clonal rearrangements of the T-cell receptor-gamma chain gene. Diagn Mol Pathol 1992;1:173-179.
18. Gribben JG, Freedman AS, Woo SD, et al. All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment. Blood 1991;78: 3275-3280.
19. Caspersson T, Zech L, Johansson C, et al. Identification of human chromosomes by DNA-binding fluorescent agents. Chromosoma 1970;30:215-227.
20. Franco V, Florena Ada Maria, Lannitto E. Splenic marginal zone lymphoma. Blood 2003;101:2464-2472.
21. Labouyrie E, Marit G, Vial J-P, et al. Intrasinusoidal bone marrow involvement by splenic lymphoma with villous lymphocytes: a helpful immunohistologic feature. Mod Pathol 1997;10:1015-1020.
22. Audouin J, Le Tourneau A, Molina T, et al. Patterns of bone marrow involvement in 58 patients presenting primary splenic marginal zone lymphoma with or without circulating villous lymphocytes. Br J Haematol 2003;122:404-412.
23. Milicevic NM, Milicevic Z, Westermann J. Lymphocyte function-associated antigen-1 and intercellular adhesion molecule-1 expression on B-cell subsets and the effect of splenectomy-experimental studies. Leuk Lymphoma 2002;43:2071-2074.
24. Nadkarni JJ, Perambakam SM, Rathore V-B, et al. Expression of adhesion molecules in B-cell chronic lymphocytic leukaemia: an analysis in lymphoid compartments: peripheral blood, bone marrow and lymph node. Cancer Biother Radiopharm 1998;4: 269-274.
25. Roussel M, Roue G, Sola B, et al. Dysfunction of the Fas apoptotic signaling pathway in persistent polyclonal B-cell lymphocytosis. Haematologica 2003;88:239-240.
26. Lancry L, Roulland S, Roue G, et al. No BCL-2 protein over expression but BCL-2/IgH rearrangements in B cells of patients with persistent polyclonal B-cell lymphocytosis. Hematol J 2001;2:228-233.
27. Mossafa H, Malaure H, Maynadie M, et al. Persistent polyclonal B lymphocytosis with binucleated lymphocytes: a study of 25 cases. Groupe Français d'Hématologie Cellulaire. Br J Haematol 1999;104:486-493.
28. Samson T, Mossafa H, Lusina D, et al. Dicentric chromosome 3 associated with binucleated lymphocytes in atypical B-cell chronic lymphoproliferative disorder. Leuk Lymphoma 2002;43:1749-1754.
29. Salcedo I, Campos-Caro A, Sampalo A, et al. Persistent polyclonal B lymphocytosis: an expansion of cells showing IgVH gene mutations and phenotypic features of normal lymphocytes from the CD27+ marginal zone B-cell compartment. Br J Haematol 2002;116:662-666.
30. Delage R, Roy J, Jacques L, et al. All patients with persistent polyclonal B cell lymphocytosis present Bcl-2/Ig gene rearrangements. Leuk Lymphoma 1998;31:567-574.
31. Callet-Bauchu E, Renard N, Gazzo S, et a]. Distribution of the cytogenetic abnormality +i(3)(q10) in persistent polyclonal B-cell lymphocytosis: a FICTION study in three cases. Br J Haematol 1997;99:531-536.
32. Lawlor E, Murray M, O'Briain DS, et al. Persistent polyclonal B lymphocytosis with Epstein-Barr virus antibodies and subsequent malignant pulmonary blastoma. J Clin Pathol 1991;44:341-342.
33. Roy J, Ryckman C, Bernier V, et al. Large cell lymphoma complicating persistent polyclonal B cell lymphocytosis. Leukemia 1998;12:1026-1030.
34. Himmelmann A, Gautschi O, Nawrath M, et al. Persistent polyclonal B-cell lymphocytosis is an expansion of functional IgD(+) CD27(+) memory B cells. Br J Haematol 2001;114:400-405.
35. Loembe MM, Neron S, Delage R, et al. Analysis of expressed V(H) genes in persistent polyclonal B cell lymphocytosis reveals absence of selection in CD27+IgM+IgD+ memory B cells. Eur J Immunol 2002;32:3678-3688.
36. Mitterer M, Pescosta N, Fend F, et al. Chronic active Epstein-Barr virus disease in a case of persistent polyclonal B-cell lymphocytosis. Br J Haematol 1995;90:526-531.