Synthesis and pharmacokinetic evaluation of novel N-acyl-cordycepin derivatives with a normal alkyl chain

European Journal of Medicinal Chemistry

Volumn 44, Issue 2, 2009, Pages 665-669

  Wei, H P ^a,b   Ye, X L ^a   Chen, Z ^a   Zhong, Y J ^a   Li, P M ^b   Pu, S C ^b   Li, X G ^a  

^a SOUTHWEST UNIVERSITY   (China)

^b Chongqing Institute of Herb Planting   (China)

Author keywords

Cordycepin; N acyl modification; Pharmacokinetics

Indexed keywords

CORDYCEPIN DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN;

ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; AREA UNDER CURVE; DEOXYADENOSINES; HALF-LIFE; METABOLIC CLEARANCE RATE; PHARMACOKINETICS; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 60149086011     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.05.013     Document Type: Article

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