The flexibility of the LeaLex Tumor Associated Antigen central fragment studied by systematic and stochastic searches as well as dynamic simulations

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 4, 2009, Pages 1514-1526

  Jackson, Trudy A ^a   Robertson, Valerie ^a   Imberty, Anne ^b   Auzanneau, France Isabelle ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b CENTRE DE RECHERCHES SUR LES MACROMOLÉCULES VÉGÉTALES CERMAV CNRS   (France)

Author keywords

Carbohydrate based anti cancer vaccines; Conformational analysis; LeaLex; Molecular dynamics; NMR spectroscopy; Stochastic search; Synthesis; Systematic search

Indexed keywords

TUMOR ANTIGEN;

ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; SIMULATION; STOCHASTIC MODEL; STRUCTURE ANALYSIS;

ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; COMPUTER SIMULATION; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOSACCHARIDES; STOCHASTIC PROCESSES; THERMODYNAMICS; TRISACCHARIDES;

EID: 60049091638     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.01.020     Document Type: Article

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