-
1
-
-
28444439801
-
Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases
-
Fanghänel J, Fischer G (2004) Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases. Front Biosci 9: 3453-3478.
-
(2004)
Front Biosci
, vol.9
, pp. 3453-3478
-
-
Fanghänel, J.1
Fischer, G.2
-
3
-
-
27744499156
-
Intrinsic dynamics of an enzyme underlies catalysis
-
Eisenmesser EZ, Millet O, Labeikovsky W, Korzhnev DM, Wolf-Watz M, Bosco DA, Skalicky JJ, Kay LE, Kern D (2005) Intrinsic dynamics of an enzyme underlies catalysis. Nature 438: 117-121.
-
(2005)
Nature
, vol.438
, pp. 117-121
-
-
Eisenmesser, E.Z.1
Millet, O.2
Labeikovsky, W.3
Korzhnev, D.M.4
Wolf-Watz, M.5
Bosco, D.A.6
Skalicky, J.J.7
Kay, L.E.8
Kern, D.9
-
4
-
-
16244419691
-
Enzyme dynamics during catalysis measured by NMR spectroscopy
-
Kern D, Eisenmesser EZ, Wolf-Watz M (2005) Enzyme dynamics during catalysis measured by NMR spectroscopy. Methods Enzymol 394: 507-524.
-
(2005)
Methods Enzymol
, vol.394
, pp. 507-524
-
-
Kern, D.1
Eisenmesser, E.Z.2
Wolf-Watz, M.3
-
5
-
-
0031568329
-
Cyclophilin A complexed with a fragment of HIV-1 gag protein: Insights into HIV-1 infectious activity
-
Zhao Y, Chen Y, Schutkowski M, Fischer G, Ke H (1997) Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity. Structure 5: 139-146.
-
(1997)
Structure
, vol.5
, pp. 139-146
-
-
Zhao, Y.1
Chen, Y.2
Schutkowski, M.3
Fischer, G.4
Ke, H.5
-
6
-
-
0029982651
-
Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization
-
Zhao Y, Ke H (1996) Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization. Biochemistry 35: 7356-7361.
-
(1996)
Biochemistry
, vol.35
, pp. 7356-7361
-
-
Zhao, Y.1
Ke, H.2
-
7
-
-
0030014678
-
Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes
-
Zhao Y, Ke H (1996) Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes. Biochemistry 35: 7362-7368.
-
(1996)
Biochemistry
, vol.35
, pp. 7362-7368
-
-
Zhao, Y.1
Ke, H.2
-
8
-
-
0027071803
-
Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition
-
Zydowsky LD, Etzkorn FA, Chang HY, Ferguson SB, Stolz LA, Ho SI, Walsh CT (1992) Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition. Protein Sci 1: 1092-1099.
-
(1992)
Protein Sci
, vol.1
, pp. 1092-1099
-
-
Zydowsky, L.D.1
Etzkorn, F.A.2
Chang, H.Y.3
Ferguson, S.B.4
Stolz, L.A.5
Ho, S.I.6
Walsh, C.T.7
-
9
-
-
0037178118
-
The mechanism of cis-trans isomerization of prolyl peptides by cyclophilin
-
Hur S, Bruice TC (2002) The mechanism of cis-trans isomerization of prolyl peptides by cyclophilin. J Am Chem Soc 124: 7303-7313.
-
(2002)
J Am Chem Soc
, vol.124
, pp. 7303-7313
-
-
Hur, S.1
Bruice, T.C.2
-
10
-
-
0345529841
-
What is so special about Arg 55 in the catalysis of cyclophilin A? insights from hybrid QM/MM simulations
-
Li G, Cui Q (2003) What is so special about Arg 55 in the catalysis of cyclophilin A? insights from hybrid QM/MM simulations. J Am Chem Soc 125: 15028-15038.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 15028-15038
-
-
Li, G.1
Cui, Q.2
-
11
-
-
4143095852
-
Protein dynamics and enzymatic catalysis: Investigating the peptidyl-prolyl cis-trans isomerization activity of cyclophilin A
-
Agarwal PK, Geist A, Gorin A (2004) Protein dynamics and enzymatic catalysis: investigating the peptidyl-prolyl cis-trans isomerization activity of cyclophilin A. Biochemistry 43: 10605-10618.
-
(2004)
Biochemistry
, vol.43
, pp. 10605-10618
-
-
Agarwal, P.K.1
Geist, A.2
Gorin, A.3
-
12
-
-
33751099086
-
Catalytic mechanism of cyclophilin as observed in molecular dynamics simulations: Pathway prediction and reconciliation of Xray crystallographic and NMR solution data
-
Trzesniak D, van Gunsteren WF (2006) Catalytic mechanism of cyclophilin as observed in molecular dynamics simulations: pathway prediction and reconciliation of Xray crystallographic and NMR solution data. Protein Sci 15: 2544-2551.
-
(2006)
Protein Sci
, vol.15
, pp. 2544-2551
-
-
Trzesniak, D.1
van Gunsteren, W.F.2
-
13
-
-
0026463503
-
Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes
-
Häkansson K, Carlsson M, Svensson LA, Liljas A (1992) Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes. J Mol Biol 227: 1192-1204.
-
(1992)
J Mol Biol
, vol.227
, pp. 1192-1204
-
-
Häkansson, K.1
Carlsson, M.2
Svensson, L.A.3
Liljas, A.4
-
14
-
-
0026526853
-
Cis-trans isomerization is rate-determining in the reactivation of denatured human carbonic anhydrase II as evidenced by proline isomerase
-
Fransson C, Freskga°rd P-O, Herbertsson H, Johansson A, Jonasson P, Ma°rtensson L-G, Svensson M, Jonsson B-H, Carlsson U (1992) Cis-trans isomerization is rate-determining in the reactivation of denatured human carbonic anhydrase II as evidenced by proline isomerase. FEBS Lett 296: 90-94.
-
(1992)
FEBS Lett
, vol.296
, pp. 90-94
-
-
Fransson, C.1
Freskga°rd, P.-O.2
Herbertsson, H.3
Johansson, A.4
Jonasson, P.5
Ma°rtensson, L.-G.6
Svensson, M.7
Jonsson, B.-H.8
Carlsson, U.9
-
15
-
-
0026499641
-
Isomerase and chaperone activity of prolyl isomerase in the folding of carbonic anhydrase
-
Freskga°rd P-O, Bergenhem N, Jonsson B-H, Svensson M, Carlsson U (1992) Isomerase and chaperone activity of prolyl isomerase in the folding of carbonic anhydrase. Science 258: 466-468.
-
(1992)
Science
, vol.258
, pp. 466-468
-
-
Freskga°rd, P.-O.1
Bergenhem, N.2
Jonsson, B.-H.3
Svensson, M.4
Carlsson, U.5
-
16
-
-
0028278089
-
Reassessment of the putative chaperone function of prolyl-cis/ trans-isomerases
-
Kern G, Kern D, Schmid FX, Fischer G (1994) Reassessment of the putative chaperone function of prolyl-cis/ trans-isomerases. FEBS Lett 348: 145-148.
-
(1994)
FEBS Lett
, vol.348
, pp. 145-148
-
-
Kern, G.1
Kern, D.2
Schmid, F.X.3
Fischer, G.4
-
17
-
-
0028928739
-
A kinetic analysis of the folding of human carbonic anhydrase II and its catalysis by cyclophilin
-
Kern G, Kern D, Schmid FX, Fischer G (1995) A kinetic analysis of the folding of human carbonic anhydrase II and its catalysis by cyclophilin. J Biol Chem 270: 740-745.
-
(1995)
J Biol Chem
, vol.270
, pp. 740-745
-
-
Kern, G.1
Kern, D.2
Schmid, F.X.3
Fischer, G.4
-
18
-
-
0027389744
-
Characterization of folding intermediates of human carbonic anhydrase II: Probing substructure by chemical labeling of SH groups introduced by site-directed mutagenesis
-
Ma°rtensson L-G, Jonsson B-H, Freskga°rd PO, Kihlgren A, Svensson M, Carlsson U (1993) Characterization of folding intermediates of human carbonic anhydrase II: probing substructure by chemical labeling of SH groups introduced by site-directed mutagenesis. Biochemistry 32: 224-231.
-
(1993)
Biochemistry
, vol.32
, pp. 224-231
-
-
Ma°rtensson, L.-G.1
Jonsson, B.-H.2
Freskga°rd, P.O.3
Kihlgren, A.4
Svensson, M.5
Carlsson, U.6
-
19
-
-
0025005004
-
Mechanistic studies of peptidyl prolyl cis-trans isomerase: Evidence for catalysis by distortion
-
Harrison RK, Stein RL (1990) Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion. Biochemistry 29: 1684-1689.
-
(1990)
Biochemistry
, vol.29
, pp. 1684-1689
-
-
Harrison, R.K.1
Stein, R.L.2
-
20
-
-
0025801571
-
Analogues of intermediates in the action of pig kidney prolidase
-
Radzicka A, Wolfenden R (1991) Analogues of intermediates in the action of pig kidney prolidase. Biochemistry 30: 4160-4164.
-
(1991)
Biochemistry
, vol.30
, pp. 4160-4164
-
-
Radzicka, A.1
Wolfenden, R.2
-
21
-
-
0030848403
-
Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate
-
Scholz C, Schindler T, Dolinski K, Heitman J, Schmid FX (1997) Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate. FEBS Lett 414: 69-73.
-
(1997)
FEBS Lett
, vol.414
, pp. 69-73
-
-
Scholz, C.1
Schindler, T.2
Dolinski, K.3
Heitman, J.4
Schmid, F.X.5
-
22
-
-
33144467755
-
Amyloid formation under physiological conditions proceeds via a native-like folding intermediate
-
Jahn TR, Parker MJ, Homans SW, Radford SE (2006) Amyloid formation under physiological conditions proceeds via a native-like folding intermediate. Nat Struct Mol Biol 13: 195-201.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 195-201
-
-
Jahn, T.R.1
Parker, M.J.2
Homans, S.W.3
Radford, S.E.4
-
23
-
-
33644813233
-
A native to amyloidogenic transition regulated by a backbone trigger
-
Eakin CM, Berman AJ, Miranker AD (2006) A native to amyloidogenic transition regulated by a backbone trigger. Nat Struct Mol Biol 13: 202-208.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 202-208
-
-
Eakin, C.M.1
Berman, A.J.2
Miranker, A.D.3
-
24
-
-
33645300736
-
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production
-
Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP (2006) The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. Nature 440: 528-534.
-
(2006)
Nature
, vol.440
, pp. 528-534
-
-
Pastorino, L.1
Sun, A.2
Lu, P.J.3
Zhou, X.Z.4
Balastik, M.5
Finn, G.6
Wulf, G.7
Lim, J.8
Li, S.H.9
Li, X.10
Xia, W.11
Nicholson, L.K.12
Lu, K.P.13
-
25
-
-
33846799138
-
Essential role of proline isomerization in stefin B tetramer formation
-
Jenko Kokalj S, Guncar G, Stern I, Morgan G, Rabzelj S, Kenig M, Staniforth RA, Waltho JP, Zerovnik E, Turk D (2007) Essential role of proline isomerization in stefin B tetramer formation. J Mol Biol 366: 1569-1579.
-
(2007)
J Mol Biol
, vol.366
, pp. 1569-1579
-
-
Jenko Kokalj, S.1
Guncar, G.2
Stern, I.3
Morgan, G.4
Rabzelj, S.5
Kenig, M.6
Staniforth, R.A.7
Waltho, J.P.8
Zerovnik, E.9
Turk, D.10
-
26
-
-
40449090759
-
A conformationally isoformic thermophilic protein with high kinetic unfolding barriers
-
Mishra R, Olofsson L, Karlsson M, Carlsson U, Nicholls IA, Hammarström P (2008) A conformationally isoformic thermophilic protein with high kinetic unfolding barriers. Cell Mol Life Sci 65: 827-839.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 827-839
-
-
Mishra, R.1
Olofsson, L.2
Karlsson, M.3
Carlsson, U.4
Nicholls, I.A.5
Hammarström, P.6
-
27
-
-
0038780573
-
Structural insights into the catalytic mechanism of cyclophilin A
-
Howard BR, Vajdos FF, Li S, Sundquist WI, Hill CP (2003) Structural insights into the catalytic mechanism of cyclophilin A. Nat Struct Biol 10: 475-481.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 475-481
-
-
Howard, B.R.1
Vajdos, F.F.2
Li, S.3
Sundquist, W.I.4
Hill, C.P.5
-
28
-
-
0026047767
-
Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121
-
Nair SK, Calderone TL, Christanson DW, Fierke C (1991) Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121. J Biol Chem 266: 17320-17325.
-
(1991)
J Biol Chem
, vol.266
, pp. 17320-17325
-
-
Nair, S.K.1
Calderone, T.L.2
Christanson, D.W.3
Fierke, C.4
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