Preventive effect of Co-administration of water containing magnesium ion on indomethacin induced lesions of gastric mucosa in adjuvant-induced arthritis rat

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 1, 2009, Pages 116-120

  Nagai, Noriaki ^a   Fukuhata, Takashi ^a   Ito, Yoshimasa ^a   Usui, Shigeyuki ^b   Hirano, Kazuyuki ^b  

^a KINKI UNIVERSITY   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Adjuvant induced arthritis; Gastric lesion; Indomethacin; Magnesium ion; Rheumatoid arthritis

Indexed keywords

BITTER WATER; CALCIUM ION; INDOMETACIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MAGNESIUM ION; NIGARI SUI; NITRIC OXIDE; POTASSIUM ION; SODIUM ION; UNCLASSIFIED DRUG; WATER;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; GENE EXPRESSION; MALE; MYCOBACTERIUM BUTYRICUM; NONHUMAN; NUCLEOTIDE SEQUENCE; PAW EDEMA; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; STOMACH HEMORRHAGE; STOMACH LESION; STOMACH PROTECTION; ULCEROGENESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; EDEMA; GASTRIC MUCOSA; GENE EXPRESSION REGULATION; INDOMETHACIN; MAGNESIUM; MALE; MINERAL WATERS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RNA, MESSENGER; STOMACH DISEASES; TIME FACTORS;

EID: 59949102062     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.116     Document Type: Article

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