메뉴 건너뛰기




Volumn 84, Issue 2, 2009, Pages 102-108

Platelet turnover, coagulation factors, and soluble markers of platelet and endothelial activation in essential thrombocythemia: Relationship with thrombosis occurrence and JAK2 V617F allele burden

Author keywords

[No Author keywords available]

Indexed keywords

ACENOCOUMAROL; ACETYLSALICYLIC ACID; ANAGRELIDE; BIOLOGICAL MARKER; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 13; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; CD40 LIGAND; D DIMER; HEMOGLOBIN; HYDROXYUREA; JANUS KINASE 2; PADGEM PROTEIN; PHOSPHORUS; PROTEIN C; PROTEIN S; PROTHROMBIN; THROMBOMODULIN; THROMBOPLASTIN; TICLOPIDINE; VON WILLEBRAND FACTOR;

EID: 59949089238     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21338     Document Type: Article
Times cited : (113)

References (45)
  • 1
    • 43949103121 scopus 로고    scopus 로고
    • Life expectancy and prognostic factors in the classic BCR/ABL-negative myeloproliferative disorders
    • Cervantes F, Passamonti F, Barosi G. Life expectancy and prognostic factors in the classic BCR/ABL-negative myeloproliferative disorders. Leukemia 2008;22:905-914.
    • (2008) Leukemia , vol.22 , pp. 905-914
    • Cervantes, F.1    Passamonti, F.2    Barosi, G.3
  • 2
    • 0034672149 scopus 로고    scopus 로고
    • Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera
    • Falanga A, Marchetti M, Evangelista V, et al. Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera. Blood 2000;96:4261-4266.
    • (2000) Blood , vol.96 , pp. 4261-4266
    • Falanga, A.1    Marchetti, M.2    Evangelista, V.3
  • 3
    • 17844390356 scopus 로고    scopus 로고
    • Leukocyte-platelet interaction in patients with essential thrombocythemia and polycythemia vera
    • Falanga A, Marchetti M, Vignoli A, et al. Leukocyte-platelet interaction in patients with essential thrombocythemia and polycythemia vera. Exp Hematol 2005;33:523-530.
    • (2005) Exp Hematol , vol.33 , pp. 523-530
    • Falanga, A.1    Marchetti, M.2    Vignoli, A.3
  • 4
    • 33644501833 scopus 로고    scopus 로고
    • Increased platelet and leukocyte activation as contributing mechanisms for thrombosis in essential thrombocythemia and correlation with the JAK2 mutational status
    • Arellano-Rodrigo E, Alvarez-Larrán A, Reverter JC, et al. Increased platelet and leukocyte activation as contributing mechanisms for thrombosis in essential thrombocythemia and correlation with the JAK2 mutational status. Haematologica 2006;91:169-175.
    • (2006) Haematologica , vol.91 , pp. 169-175
    • Arellano-Rodrigo, E.1    Alvarez-Larrán, A.2    Reverter, J.C.3
  • 5
    • 0032400835 scopus 로고    scopus 로고
    • P-selectin and platelet clearance
    • Berger G, Hartwell DW, Wagner DD. P-selectin and platelet clearance. Blood 1998;92:4446-4452.
    • (1998) Blood , vol.92 , pp. 4446-4452
    • Berger, G.1    Hartwell, D.W.2    Wagner, D.D.3
  • 6
    • 0037877918 scopus 로고    scopus 로고
    • CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation
    • Inwald DP, McDowall A, Peters MJ, et al. CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. Circ Res 2003;92:1041-1048.
    • (2003) Circ Res , vol.92 , pp. 1041-1048
    • Inwald, D.P.1    McDowall, A.2    Peters, M.J.3
  • 7
    • 0033782228 scopus 로고    scopus 로고
    • Role of P-selectin and CD40 ligand in the induction of monocyte tissue factor expression
    • Lindmark E, Tenno T, Seigbahn A. Role of P-selectin and CD40 ligand in the induction of monocyte tissue factor expression. Arterioscler Thromb Vasc Biol 2000;20:2322-2328.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2322-2328
    • Lindmark, E.1    Tenno, T.2    Seigbahn, A.3
  • 8
    • 0142091359 scopus 로고    scopus 로고
    • Soluble CD40 ligand induces β3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling
    • Prasad KSS, Andre P, He M, et al. Soluble CD40 ligand induces β3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling. Proc Natl Acad Sci USA 2003;100:12367-12371.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12367-12371
    • Prasad, K.S.S.1    Andre, P.2    He, M.3
  • 9
    • 50449098285 scopus 로고    scopus 로고
    • Mechanisms of thrombus formation
    • Furie B, Furie BC. Mechanisms of thrombus formation. N Engl J Med 2008;359:938-949.
    • (2008) N Engl J Med , vol.359 , pp. 938-949
    • Furie, B.1    Furie, B.C.2
  • 10
    • 0037456769 scopus 로고    scopus 로고
    • Soluble CD40 ligand in acute coronary syndromes
    • Heeschen C, Dimmeler S, Hamm CW, et al. Soluble CD40 ligand in acute coronary syndromes. N Engl J Med 2003;348:1104-1111.
    • (2003) N Engl J Med , vol.348 , pp. 1104-1111
    • Heeschen, C.1    Dimmeler, S.2    Hamm, C.W.3
  • 11
    • 0038652166 scopus 로고    scopus 로고
    • Upregulation of CD40 - CD40 ligand (CD154) in patients with acute cerebral ischemia
    • Garlichs CD, Kozina S, Fateh-Moghadam S, et al. Upregulation of CD40 - CD40 ligand (CD154) in patients with acute cerebral ischemia. Stroke 2003;34:1412-1418.
    • (2003) Stroke , vol.34 , pp. 1412-1418
    • Garlichs, C.D.1    Kozina, S.2    Fateh-Moghadam, S.3
  • 12
    • 33645456050 scopus 로고    scopus 로고
    • Can haematological tests predict cardiovascular risk? The 2005 Kettle lecture
    • Lowe GDO. Can haematological tests predict cardiovascular risk? The 2005 Kettle lecture. Br J Haematol 2006;133:232-250.
    • (2006) Br J Haematol , vol.133 , pp. 232-250
    • Lowe, G.D.O.1
  • 13
    • 0032519972 scopus 로고    scopus 로고
    • Correlation of thrombosis with increased platelet turnover in thrombocytosis
    • Rinder HM, Schuster JE, Rinder CS, et al. Correlation of thrombosis with increased platelet turnover in thrombocytosis. Blood 1998;91:1288-1294.
    • (1998) Blood , vol.91 , pp. 1288-1294
    • Rinder, H.M.1    Schuster, J.E.2    Rinder, C.S.3
  • 14
    • 0031757218 scopus 로고    scopus 로고
    • Differences in platelet α-granule release between normals and immune thrombocytopenic patients and between young and old platelets
    • Rinder HM, Tracey JB, Recht M, et al. Differences in platelet α-granule release between normals and immune thrombocytopenic patients and between young and old platelets. Thromb Haemost 1998;80:457-462.
    • (1998) Thromb Haemost , vol.80 , pp. 457-462
    • Rinder, H.M.1    Tracey, J.B.2    Recht, M.3
  • 15
    • 0032817084 scopus 로고    scopus 로고
    • Relationship between size and thiazole orange fluorescence of platelets in patients undergoing high-dose chemotherapy
    • Balduini CL, Noris P, Spedini P, et al. Relationship between size and thiazole orange fluorescence of platelets in patients undergoing high-dose chemotherapy. Br J Haematol 1999;106:202-207.
    • (1999) Br J Haematol , vol.106 , pp. 202-207
    • Balduini, C.L.1    Noris, P.2    Spedini, P.3
  • 16
    • 0030794650 scopus 로고    scopus 로고
    • The origin of P-selectin as a circulating plasma protein
    • Fijnheer R, Frijns CJ, Korteweg J, et al. The origin of P-selectin as a circulating plasma protein. Thromb Haemost 1997;77:181-185.
    • (1997) Thromb Haemost , vol.77 , pp. 181-185
    • Fijnheer, R.1    Frijns, C.J.2    Korteweg, J.3
  • 17
    • 0036529828 scopus 로고    scopus 로고
    • Increased soluble and platelet-associated CD40 ligand in essential thrombocythemia and reactive thrombocytosis
    • Viallard JF, Solanilla A, Gauthier B, et al. Increased soluble and platelet-associated CD40 ligand in essential thrombocythemia and reactive thrombocytosis. Blood 2002;99:2612-2614.
    • (2002) Blood , vol.99 , pp. 2612-2614
    • Viallard, J.F.1    Solanilla, A.2    Gauthier, B.3
  • 18
    • 0033976695 scopus 로고    scopus 로고
    • Markers of endothelial and platelet status in patients with essential thrombocythemia and polycythemia vera
    • Musolino C, Alonci A, Bellomo G, et al. Markers of endothelial and platelet status in patients with essential thrombocythemia and polycythemia vera. Hematology 2000;4:397-402.
    • (2000) Hematology , vol.4 , pp. 397-402
    • Musolino, C.1    Alonci, A.2    Bellomo, G.3
  • 19
    • 0034610379 scopus 로고    scopus 로고
    • Pro-coagulant state resulting from high levels of soluble P-selectin in blood
    • André P, Hartwell D, Hrachovinová I, et al. Pro-coagulant state resulting from high levels of soluble P-selectin in blood. Proc Natl Acad Sci USA 2000;97:13835-13840.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13835-13840
    • André, P.1    Hartwell, D.2    Hrachovinová, I.3
  • 20
    • 18244378804 scopus 로고    scopus 로고
    • Effect of P-selectin on phosphatidylserine exposure and surface-dependent thrombin generation on monocytes
    • del Conde I, Nabi F, Tonda R, et al. Effect of P-selectin on phosphatidylserine exposure and surface-dependent thrombin generation on monocytes. Arterioscler Thromb Vasc Biol 2005;25:1065-1070.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1065-1070
    • del Conde, I.1    Nabi, F.2    Tonda, R.3
  • 21
    • 27644446835 scopus 로고    scopus 로고
    • CD40 ligand influences platelet release of reactive oxygen intermediates
    • Chakrabarti S, Varghese S, Vitseva O, et al. CD40 ligand influences platelet release of reactive oxygen intermediates. Arterioscler Thromb Vasc Biol 2005;25:2428-2434.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2428-2434
    • Chakrabarti, S.1    Varghese, S.2    Vitseva, O.3
  • 22
    • 33749346098 scopus 로고    scopus 로고
    • Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury
    • Khan SY, Kelher MR, Heal JM, et al. Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury. Blood 2006;108:2455-2462.
    • (2006) Blood , vol.108 , pp. 2455-2462
    • Khan, S.Y.1    Kelher, M.R.2    Heal, J.M.3
  • 23
    • 33750991098 scopus 로고    scopus 로고
    • Inhibition of tissue factor expression by hydroxyurea in polymorphonuclear leukocytes from patients with myeloproliferative disorders: A new effect for an old drug?
    • Maugeri N, Giordano G, Petrilli MP, et al. Inhibition of tissue factor expression by hydroxyurea in polymorphonuclear leukocytes from patients with myeloproliferative disorders: A new effect for an old drug? J Thromb Haemost 2006;3:245-250.
    • (2006) J Thromb Haemost , vol.3 , pp. 245-250
    • Maugeri, N.1    Giordano, G.2    Petrilli, M.P.3
  • 24
    • 0030883109 scopus 로고    scopus 로고
    • Enhanced generation of monocyte tissue factor and increased plasma prothrombin fragment 1 +2levels in patients with polycythemia vera: Mechanism of activation of blood coagulation
    • Kornberg A, Rahimi-Levene N, Yona R, et al. Enhanced generation of monocyte tissue factor and increased plasma prothrombin fragment 1 +2levels in patients with polycythemia vera: Mechanism of activation of blood coagulation. Am J Hematol 1997;56:5-11.
    • (1997) Am J Hematol , vol.56 , pp. 5-11
    • Kornberg, A.1    Rahimi-Levene, N.2    Yona, R.3
  • 25
    • 34247155769 scopus 로고    scopus 로고
    • V617F JAK-2 mutation in patients with essential thrombocythemia: Relation to platelet, granulocyte, and plasma hemostatic and inflammatory molecules
    • Falanga A, Marchetti M, Vignoli A, et al. V617F JAK-2 mutation in patients with essential thrombocythemia: Relation to platelet, granulocyte, and plasma hemostatic and inflammatory molecules. Exp Hematol 2007;35:702-711.
    • (2007) Exp Hematol , vol.35 , pp. 702-711
    • Falanga, A.1    Marchetti, M.2    Vignoli, A.3
  • 26
    • 58149145904 scopus 로고    scopus 로고
    • Marchetti M, Castoldi E, Spronk HMH, et al. Thrombin generation and activated protein C resistance in patients with essential thrombocythemia and polycythemia vera. Blood 2008;112:4061-4068; Prepublished on September 3, 2008, as DOI 10.1182/blood-2008-06-164087.
    • Marchetti M, Castoldi E, Spronk HMH, et al. Thrombin generation and activated protein C resistance in patients with essential thrombocythemia and polycythemia vera. Blood 2008;112:4061-4068; Prepublished on September 3, 2008, as DOI 10.1182/blood-2008-06-164087.
  • 27
    • 0029877730 scopus 로고    scopus 로고
    • Reduction of antithrombin III, protein C, and protein S levels and activated protein C resistance in polycythemia vera and essential thrombocythemia patients with thrombosis
    • Bucalossi A, Marotta G, Bigazzi C, et al. Reduction of antithrombin III, protein C, and protein S levels and activated protein C resistance in polycythemia vera and essential thrombocythemia patients with thrombosis. Am J Hematol 1996;52:14-20.
    • (1996) Am J Hematol , vol.52 , pp. 14-20
    • Bucalossi, A.1    Marotta, G.2    Bigazzi, C.3
  • 28
    • 49849093307 scopus 로고    scopus 로고
    • Increased acquired activated protein C resistance in unselected patients with hematological malignances
    • Negaard HFS, Iversen PO, Østenstad B, et al. Increased acquired activated protein C resistance in unselected patients with hematological malignances. J Thromb Haemost 2008;6:1482-1487.
    • (2008) J Thromb Haemost , vol.6 , pp. 1482-1487
    • Negaard, H.F.S.1    Iversen, P.O.2    Østenstad, B.3
  • 29
    • 0036176284 scopus 로고    scopus 로고
    • Frequent occurrence of anticardiolipin antibodies, factor V Leiden mutation, and perturbed endothelial function in chronic myeloproliferative disorders
    • Jensen MK, de Nully Brown P, Thorsen S, Hasselbalch HC. Frequent occurrence of anticardiolipin antibodies, factor V Leiden mutation, and perturbed endothelial function in chronic myeloproliferative disorders. Am J Hematol 2002;69:185-191.
    • (2002) Am J Hematol , vol.69 , pp. 185-191
    • Jensen, M.K.1    de Nully Brown, P.2    Thorsen, S.3    Hasselbalch, H.C.4
  • 30
    • 18744408753 scopus 로고    scopus 로고
    • Clinical significance of acquired activated protein C resistance in patients with systemic lupus erythematosus
    • Munõz-Rodríguez FJ, Reverter JC, Font J, et al. Clinical significance of acquired activated protein C resistance in patients with systemic lupus erythematosus. Lupus 2002;11:730-735.
    • (2002) Lupus , vol.11 , pp. 730-735
    • Munõz-Rodríguez, F.J.1    Reverter, J.C.2    Font, J.3
  • 31
    • 34447619693 scopus 로고    scopus 로고
    • Platelet and coagulation activation markers in myeloproliferative diseases: Relationships with JAK2 V617F status, clonality and antiphospholipid antibodies
    • Robertson B, Urquhart C, Ford I, et al. Platelet and coagulation activation markers in myeloproliferative diseases: Relationships with JAK2 V617F status, clonality and antiphospholipid antibodies. J Thromb Haemost 2007;5:1679-1685.
    • (2007) J Thromb Haemost , vol.5 , pp. 1679-1685
    • Robertson, B.1    Urquhart, C.2    Ford, I.3
  • 32
    • 0036433010 scopus 로고    scopus 로고
    • Kinetics of thrombomodulin release and endothelial cell injury by neutrophil-derived proteases and oxygen radicals
    • Boehme MWJ, Galle P, Stremmel W. Kinetics of thrombomodulin release and endothelial cell injury by neutrophil-derived proteases and oxygen radicals. Immunology 2002;107:340-349.
    • (2002) Immunology , vol.107 , pp. 340-349
    • Boehme, M.W.J.1    Galle, P.2    Stremmel, W.3
  • 33
    • 33646406275 scopus 로고    scopus 로고
    • Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders
    • Passamonti F, Rumi E, Pietra D, et al. Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders. Blood 2006;107:3676-3682.
    • (2006) Blood , vol.107 , pp. 3676-3682
    • Passamonti, F.1    Rumi, E.2    Pietra, D.3
  • 34
    • 41249088995 scopus 로고    scopus 로고
    • Increased platelet, leukocyte and coagulation activation in primary myelofibrosis
    • Alvarez-Larrán A, Arellano-Rodrigo E, Reverter JC, et al. Increased platelet, leukocyte and coagulation activation in primary myelofibrosis. Ann Hematol 2008;87:269-276.
    • (2008) Ann Hematol , vol.87 , pp. 269-276
    • Alvarez-Larrán, A.1    Arellano-Rodrigo, E.2    Reverter, J.C.3
  • 35
    • 0026662994 scopus 로고
    • Human neutrophils synthesize thrombomodulin that does not promote thrombin-dependent protein C activation
    • Conway EM, Nowakowski B, Steiner-Mosonyi M. Human neutrophils synthesize thrombomodulin that does not promote thrombin-dependent protein C activation. Blood 1992;80:1254-1263.
    • (1992) Blood , vol.80 , pp. 1254-1263
    • Conway, E.M.1    Nowakowski, B.2    Steiner-Mosonyi, M.3
  • 36
    • 33646546386 scopus 로고    scopus 로고
    • The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
    • Jamieson CH, Gotlib J, Durocher JA, et al. The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci USA 2006;103:6224-6229.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6224-6229
    • Jamieson, C.H.1    Gotlib, J.2    Durocher, J.A.3
  • 37
    • 53449099681 scopus 로고    scopus 로고
    • Sozer S, Wang X, Zhang W, et al. Circulating angiogenic monocyte progenitor cells are reduced in JAK2V617F high allele burden myeloproliferative disorders. Blood Cells Mol Dis 2008;41:284-291; Prepublished on August 19, 2008, as DOI 10.1016/j.bcmd. 2008.06.008.
    • Sozer S, Wang X, Zhang W, et al. Circulating angiogenic monocyte progenitor cells are reduced in JAK2V617F high allele burden myeloproliferative disorders. Blood Cells Mol Dis 2008;41:284-291; Prepublished on August 19, 2008, as DOI 10.1016/j.bcmd. 2008.06.008.
  • 38
    • 50849103654 scopus 로고    scopus 로고
    • Effect of JAK2 V617F on thrombotic risk in patients with essential thrombocythemia: Measuring the uncertain
    • Ziakas PD. Effect of JAK2 V617F on thrombotic risk in patients with essential thrombocythemia: Measuring the uncertain. Haematologica 2008;93:1412-1414.
    • (2008) Haematologica , vol.93 , pp. 1412-1414
    • Ziakas, P.D.1
  • 39
    • 54049086618 scopus 로고    scopus 로고
    • Thrombocytosis and leukocytosis interaction in vascular complications of essential thrombocythemia
    • Carobbio A, Finazzi G, Antonioli E, et al. Thrombocytosis and leukocytosis interaction in vascular complications of essential thrombocythemia. Blood 2008;112:3135-3137.
    • (2008) Blood , vol.112 , pp. 3135-3137
    • Carobbio, A.1    Finazzi, G.2    Antonioli, E.3
  • 40
    • 34249071097 scopus 로고    scopus 로고
    • Clinical correlates of JAK2 V617F allele burden in essential thrombocythemia
    • Kittur J, Knudson RA, Lasho TL, et al. Clinical correlates of JAK2 V617F allele burden in essential thrombocythemia. Cancer 2007;109:2279-2284.
    • (2007) Cancer , vol.109 , pp. 2279-2284
    • Kittur, J.1    Knudson, R.A.2    Lasho, T.L.3
  • 41
    • 38549135526 scopus 로고    scopus 로고
    • Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia
    • Antonioli E, Guglielmelli P, Poli G, et al. Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia. Haematologica 2008;93:41-48.
    • (2008) Haematologica , vol.93 , pp. 41-48
    • Antonioli, E.1    Guglielmelli, P.2    Poli, G.3
  • 42
    • 45749098579 scopus 로고    scopus 로고
    • Leukocytosis and risk stratification assessment in essential thrombocythemia
    • Carobbio A, Antonioli E, Guglielmelli P, et al. Leukocytosis and risk stratification assessment in essential thrombocythemia. J Clin Oncol 2008;26:2732-2736.
    • (2008) J Clin Oncol , vol.26 , pp. 2732-2736
    • Carobbio, A.1    Antonioli, E.2    Guglielmelli, P.3
  • 43
    • 34548242134 scopus 로고    scopus 로고
    • The quantitative JAK2 V617F neutrophil allele burden does not correlate with thrombotic risk in essential thrombocytosis
    • Pemmaraju N, Moliterno AR, Williams DM, et al. The quantitative JAK2 V617F neutrophil allele burden does not correlate with thrombotic risk in essential thrombocytosis. Leukemia 2007;21:2210-2212.
    • (2007) Leukemia , vol.21 , pp. 2210-2212
    • Pemmaraju, N.1    Moliterno, A.R.2    Williams, D.M.3
  • 44
    • 0031046485 scopus 로고    scopus 로고
    • Experience of the Polycythemia vera study group with essential thrombocythemia: A final report on diagnostic criteria, survival, and leukemic transition by treatment
    • Murphy S, Peterson P, Iland H, Laszlo J. Experience of the Polycythemia vera study group with essential thrombocythemia: A final report on diagnostic criteria, survival, and leukemic transition by treatment. Semin Hematol 1997; 34:29-39.
    • (1997) Semin Hematol , vol.34 , pp. 29-39
    • Murphy, S.1    Peterson, P.2    Iland, H.3    Laszlo, J.4
  • 45
    • 33645400695 scopus 로고    scopus 로고
    • X-inactivation based clonality analysis and quantitative JAK2V617F assessment reveals a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F negative ET and MMM patients with clonal hematopoiesis
    • Levine RL, Belisle C, Wadleigh M, et al. X-inactivation based clonality analysis and quantitative JAK2V617F assessment reveals a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F negative ET and MMM patients with clonal hematopoiesis. Blood 2006;107:4139-4141.
    • (2006) Blood , vol.107 , pp. 4139-4141
    • Levine, R.L.1    Belisle, C.2    Wadleigh, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.