Effective use of JC virus PCR for diagnosis of progressive multifocal leukoencephalopathy

Journal of Medical Microbiology

Volumn 58, Issue 2, 2009, Pages 253-255

  Wang, Yihong ^a   Kirby, James E ^a   Qian, Qinfang ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CD4 LYMPHOCYTE COUNT; CEREBROSPINAL FLUID ANALYSIS; DIAGNOSTIC VALUE; HIGH RISK PATIENT; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNOCOMPROMISED PATIENT; JC VIRUS; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; PROTEIN CEREBROSPINAL FLUID LEVEL;

CD4 LYMPHOCYTE COUNT; CEREBROSPINAL FLUID; HIV INFECTIONS; HUMANS; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDIES;

EID: 59949086428     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.004432-0     Document Type: Article

References (14)

1. Antinori, A., Ammassari, A., De Luca, A., Cingolani, A., Murri, R., Scoppettuolo, G., Fortini, M., Tartaglione, T., Larocca, L. M. & other authors (1997). Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiologic characteristics combined with polymerase chain reaction assays in CSF. Neurology 48, 687-694.
2. Berger, J. R., Kaszovitz, B., Post, M. J. & Dickinson, G. (1987). Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. A review of the literature with a report of sixteen cases. Ann Intern Med 107, 78-87.
3. Berger, J. R., Pall, L., Lanska, D. & Whiteman, M. (1998). Progressive multifocal leukoencephalopathy in patients with HIV infection. J Neurovirol 4, 59-68.
4. Cinque, P., Vago, L., Dahl, H., Brytting, M., Terreni, M. R., Fornara, C., Racca, S., Castagna, A., Monforte, A. D. & other authors (1996). Polymerase chain reaction on cerebrospinal fluid for diagnosis of virus-associated opportunistic diseases of the central nervous system in HIV-infected patients. AIDS 10, 951-958.
5. Di Giambenedetto, S., Vago, G., Pompucci, A., Scoppettuolo, G., Cingolani, A., Marzocchetti, A., Tumbarello, M., Cauda, R. & De Luca, A. (2004). Fatal inflammatory AIDS-associated PML with high CD4 counts on HAART: a new clinical entity? Neurology 63, 2452-2453.
6. Koralnik, I. J. (2006). Progressive multifocal leukoencephalopathy revisited: has the disease outgrown its name? Ann Neurol 60, 162-173.
7. Koralnik, I. J., Boden, D., Mai, V. X., Lord, C. L. & Letvin, N. L. (1999). JC virus DNA load in patients with and without progressive multifocal leukoencephalopathy. Neurology 52, 253-260.
8. Martínez, A. J., Sell, M., Mitrovics, T., Stoltenburg- Didinger, G., Iglesias-Rozas, J. R., Giraldo-Velásquez, M. A., Gosztonyi, G., Schneider, V. & Cenrós-Navarro, J. (1995). The neuropathology and epidemiology of AIDS. A Berlin experience. A review of 200 cases. Pathol Res Pract 191, 427-443.
9. Marzocchetti, A., Di Giambenedetto, S., Cingolani, A., Ammassari, A., Cauda, R. & De Luca, A. (2005). Reduced rate of diagnostic positive detection of JC virus DNA in cerebrospinal fluid in cases of suspected progressive multifocal leukoencephalopathy in the era of potent antiretroviral therapy. J Clin Microbiol 43, 4175-4177.
10. Miralles, P., Berenguer, J., Garcýa de Viedma, D., Padilla, B., Cosin, J., López-Bernaldo de Quirós, J. C., Muñoz, L., Moreno, S. & Bouza, E. (1998). Treatment of AIDS-associated progressive multifocal leukoencephalopathy with highly active antiretroviral therapy. AIDS 12, 2467-2472.
11. Murphy, D. G., Côte, L., Fauvel, M., René, P. & Vincelette, J. (2000). Multicenter comparison of Roche COBAS AMPLICOR MONITOR version 1.5, Organon Teknika NucliSens QT with Extractor, and Bayer Quantiplex version 3.0 for quantification of human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 38, 4034-4041.
12. Olsen, W. L., Longo, F. M., Mills, C. M. & Norman, D. (1988). White matter disease in AIDS: findings at MR imaging. Radiology 169, 445-448.
13. Ryschkewitsch, C., Jensen, P., Hou, J., Gahle, G., Fischer, S. & Major, E. O. (2004). Comparison of PCR- Southern hybridization and quantitative real-time PCR for the detection of JC and BK viral nucleotide sequences in urine and cerebrospinal fluid. JVirol Methods 121, 217-221.
14. Tang, Y. W., Jr, Hibbs, K., Tau, R., Qian, Q., Skarhus, H. A., Amith, T. F. & Persing, D. H. (1999). Effective use ofpolymerase chain reaction for diagnosis of central nervous system infections. Clin Infect Dis 29, 803-806.