-
1
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J., Kleinman W.A., Singh L., Singh G., and Raufman J.P. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 15 (1992) 7402-7405
-
(1992)
J Biol Chem
, vol.15
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
Singh, G.4
Raufman, J.P.5
-
2
-
-
0031040794
-
Tissue-specific expression of unique mRNAs that encode proglucagon-derived peptides or exendin 4 in the lizard
-
Chen Y.E., and Drucker D.J. Tissue-specific expression of unique mRNAs that encode proglucagon-derived peptides or exendin 4 in the lizard. J Biol Chem 272 (1997) 4108-4115
-
(1997)
J Biol Chem
, vol.272
, pp. 4108-4115
-
-
Chen, Y.E.1
Drucker, D.J.2
-
3
-
-
0037850667
-
Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes
-
Fineman M.S., Bicsak T.A., Shen L.Z., Taylor K., Gaines E., Varns A., Kim D., and Baron A.D. Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes. Diabetes Care 26 (2003) 2370-2377
-
(2003)
Diabetes Care
, vol.26
, pp. 2370-2377
-
-
Fineman, M.S.1
Bicsak, T.A.2
Shen, L.Z.3
Taylor, K.4
Gaines, E.5
Varns, A.6
Kim, D.7
Baron, A.D.8
-
4
-
-
0347360186
-
Pharmacology of exenatide (synthetic exedin-4): a potential therapeutic for improved glycemic control of type 2 diabetes
-
Nielsen L.L., Young A.A., and Parkes D.G. Pharmacology of exenatide (synthetic exedin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Regul Pept 117 (2004) 77-88
-
(2004)
Regul Pept
, vol.117
, pp. 77-88
-
-
Nielsen, L.L.1
Young, A.A.2
Parkes, D.G.3
-
5
-
-
0036312680
-
Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4
-
Tourrel C., Bailbe D., Lacorne M., Meile M.J., Kergoat M., and Portha B. Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. Diabetes 51 (2002) 1443-1452
-
(2002)
Diabetes
, vol.51
, pp. 1443-1452
-
-
Tourrel, C.1
Bailbe, D.2
Lacorne, M.3
Meile, M.J.4
Kergoat, M.5
Portha, B.6
-
6
-
-
0030068620
-
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
-
Willms B., Werner J., Holst J.J., Orskov C., Creutzfeldt W., and Nauck M.A. Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab 81 (1996) 327-332
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 327-332
-
-
Willms, B.1
Werner, J.2
Holst, J.J.3
Orskov, C.4
Creutzfeldt, W.5
Nauck, M.A.6
-
7
-
-
23844554610
-
Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice
-
Talsania T., Anini Y., Siu S., Drucker D.J., and Brubaker P.L. Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology 146 (2005) 3748-3756
-
(2005)
Endocrinology
, vol.146
, pp. 3748-3756
-
-
Talsania, T.1
Anini, Y.2
Siu, S.3
Drucker, D.J.4
Brubaker, P.L.5
-
8
-
-
0034456212
-
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
-
Szayna M., Doyle M.E., Betkey J.A., Holloway H.W., Spencer R.G., Greig N.H., and Egan J.M. Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats. Endocrinology 141 (2000) 1936-1941
-
(2000)
Endocrinology
, vol.141
, pp. 1936-1941
-
-
Szayna, M.1
Doyle, M.E.2
Betkey, J.A.3
Holloway, H.W.4
Spencer, R.G.5
Greig, N.H.6
Egan, J.M.7
-
9
-
-
23844526330
-
Effects of GLP-1 and exendins on kinase activity, 2-deoxy-d-glucose transport, lipolysis and lipogenesis in adipocytes from normal and streptozotocin-induced type 2 diabetic rats
-
Sancho V., Trigo M.V., González N., Valverde I., Malaisse W.J., and Villanueva-Peñacarrillo M.L. Effects of GLP-1 and exendins on kinase activity, 2-deoxy-d-glucose transport, lipolysis and lipogenesis in adipocytes from normal and streptozotocin-induced type 2 diabetic rats. J Mol Endocrinol 35 (2005) 27-38
-
(2005)
J Mol Endocrinol
, vol.35
, pp. 27-38
-
-
Sancho, V.1
Trigo, M.V.2
González, N.3
Valverde, I.4
Malaisse, W.J.5
Villanueva-Peñacarrillo, M.L.6
-
10
-
-
0031149863
-
Exendin-4 agonist and exendin(9-39)amide antagonist of the GLP-1(7-36)amide effects in liver and muscle
-
Alcántara A.I., Morales M., Delgado E., López-Delgado M.I., Clemente F., Luque M.A., Malaisse W.J., Valverde I., and Villanueva-Peñacarrillo M.L. Exendin-4 agonist and exendin(9-39)amide antagonist of the GLP-1(7-36)amide effects in liver and muscle. Arch Biochem Biophys 341 (1997) 1-7
-
(1997)
Arch Biochem Biophys
, vol.341
, pp. 1-7
-
-
Alcántara, A.I.1
Morales, M.2
Delgado, E.3
López-Delgado, M.I.4
Clemente, F.5
Luque, M.A.6
Malaisse, W.J.7
Valverde, I.8
Villanueva-Peñacarrillo, M.L.9
-
11
-
-
0036305993
-
GLP-1 and glucose metabolism in human myocytes
-
Luque M.A., González N., Márquez L., Acitores A., Redondo A., Morales M., Valverde I., and Villanueva-Peñacarrillo M.L. GLP-1 and glucose metabolism in human myocytes. J Endocrinol 173 (2002) 465-473
-
(2002)
J Endocrinol
, vol.173
, pp. 465-473
-
-
Luque, M.A.1
González, N.2
Márquez, L.3
Acitores, A.4
Redondo, A.5
Morales, M.6
Valverde, I.7
Villanueva-Peñacarrillo, M.L.8
-
12
-
-
0028925896
-
Glucagon-like peptide-1 binding to rat skeletal muscle
-
Delgado E., Luque M.A., Alcántara A., Trapote M.A., Clemente F., Galera C., Valverde I., and Villanueva-Peñacarrillo M.L. Glucagon-like peptide-1 binding to rat skeletal muscle. Peptides 16 (1995) 225-229
-
(1995)
Peptides
, vol.16
, pp. 225-229
-
-
Delgado, E.1
Luque, M.A.2
Alcántara, A.3
Trapote, M.A.4
Clemente, F.5
Galera, C.6
Valverde, I.7
Villanueva-Peñacarrillo, M.L.8
-
13
-
-
0026775150
-
Expression clonning of the pancreatic beta-cell receptor for the gluco-incretin hormone glucagon-like peptide-1
-
Thorens B. Expression clonning of the pancreatic beta-cell receptor for the gluco-incretin hormone glucagon-like peptide-1. Proc Natl Acad Sci U S A 89 (1992) 8641-8645
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8641-8645
-
-
Thorens, B.1
-
14
-
-
52049122152
-
Characteristics of the GLP-1 and exendins action upon glucose transport and metabolism in type 2 diabetic rat skeletal muscle
-
Arnés L., González N., Tornero-Esteban P., Sancho V., Acitores A., Valverde I., Delgado E., and Villanueva-Peñacarrillo M.L. Characteristics of the GLP-1 and exendins action upon glucose transport and metabolism in type 2 diabetic rat skeletal muscle. Int J Mol Med 22 (2008) 127-132
-
(2008)
Int J Mol Med
, vol.22
, pp. 127-132
-
-
Arnés, L.1
González, N.2
Tornero-Esteban, P.3
Sancho, V.4
Acitores, A.5
Valverde, I.6
Delgado, E.7
Villanueva-Peñacarrillo, M.L.8
-
15
-
-
1842478323
-
Cell signalling of the glucagon like peptide-1 action in rat skeletal muscle
-
Acitores A., González N., Sancho V., Valverde I., and Villanueva-Peñacarrillo M.L. Cell signalling of the glucagon like peptide-1 action in rat skeletal muscle. J Endocrinol 180 (2004) 389-398
-
(2004)
J Endocrinol
, vol.180
, pp. 389-398
-
-
Acitores, A.1
González, N.2
Sancho, V.3
Valverde, I.4
Villanueva-Peñacarrillo, M.L.5
-
16
-
-
12344301360
-
Effect of GLP-1 on glucose transport and its cell signalling in human myocytes
-
González N., Acitores A., Sancho V., Valverde I., and Villanueva-Peñacarrillo M.L. Effect of GLP-1 on glucose transport and its cell signalling in human myocytes. Regul Pept 126 (2005) 203-211
-
(2005)
Regul Pept
, vol.126
, pp. 203-211
-
-
González, N.1
Acitores, A.2
Sancho, V.3
Valverde, I.4
Villanueva-Peñacarrillo, M.L.5
-
17
-
-
0034780586
-
Effect of GLP-1 treatment on GLUT2 and GLUT4 expression in NIDDM and IDDM rats
-
Villanueva-Peñacarrillo M.L., Puente J., Redondo A., Clemente F., and Valverde I. Effect of GLP-1 treatment on GLUT2 and GLUT4 expression in NIDDM and IDDM rats. Endocrine 15 (2001) 241-248
-
(2001)
Endocrine
, vol.15
, pp. 241-248
-
-
Villanueva-Peñacarrillo, M.L.1
Puente, J.2
Redondo, A.3
Clemente, F.4
Valverde, I.5
-
18
-
-
0018690111
-
Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes
-
Portha B., Picon L., and Rosselin G. Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes. Diabetologia 17 (1979) 371-377
-
(1979)
Diabetologia
, vol.17
, pp. 371-377
-
-
Portha, B.1
Picon, L.2
Rosselin, G.3
-
19
-
-
0027935452
-
Impaired in vivo insulin secretion in response to non-glucidic secretagogues in adult rats after neonatal streptozotocin
-
Vicent D., Villanueva-Peñacarrillo M.L., Valverde I., and Malaisse W.J. Impaired in vivo insulin secretion in response to non-glucidic secretagogues in adult rats after neonatal streptozotocin. Acta Diabetol 31 (1994) 133-137
-
(1994)
Acta Diabetol
, vol.31
, pp. 133-137
-
-
Vicent, D.1
Villanueva-Peñacarrillo, M.L.2
Valverde, I.3
Malaisse, W.J.4
-
20
-
-
0031918704
-
Glycogen assay for diagnosis of female genital Chlamydia trachomatis infection
-
Chun Y., and Yin Z.D. Glycogen assay for diagnosis of female genital Chlamydia trachomatis infection. J Clin Microbiol 36 (1998) 1081-1082
-
(1998)
J Clin Microbiol
, vol.36
, pp. 1081-1082
-
-
Chun, Y.1
Yin, Z.D.2
-
22
-
-
0023902258
-
Stimulation by d-glucose of protein biosynthesis in tumoral insulin-producing cells (RINm5F line)
-
Valverde I., Barreto M., and Malaisse W.J. Stimulation by d-glucose of protein biosynthesis in tumoral insulin-producing cells (RINm5F line). Endocrinology 122 (1988) 1443-1448
-
(1988)
Endocrinology
, vol.122
, pp. 1443-1448
-
-
Valverde, I.1
Barreto, M.2
Malaisse, W.J.3
-
23
-
-
0028139157
-
Potent glycogenic effect of GLP-1 (7-36) amide in rat skeletal muscle
-
Villanueva-Peñacarrillo M.L., Alcántara A., Clemente F., Delgado E., and Valverde I. Potent glycogenic effect of GLP-1 (7-36) amide in rat skeletal muscle. Diabetologia 37 (1994) 1163-1166
-
(1994)
Diabetologia
, vol.37
, pp. 1163-1166
-
-
Villanueva-Peñacarrillo, M.L.1
Alcántara, A.2
Clemente, F.3
Delgado, E.4
Valverde, I.5
-
24
-
-
0017184389
-
A rapid and sensitive method for the quantization of microgram quantities of protein utilizing the principle of protein dye binding
-
Bradford M.M. A rapid and sensitive method for the quantization of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72 (1976) 248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
25
-
-
0023683874
-
An in vitro human muscle preparation suitable for metabolic studies
-
Dohm G.L., Tapscott E.B., Pories W.J., Dabbs D.J., Flickinger E.G., Meelheim T.F., Atkinson S.M., Elton C.W., and Caro J.F. An in vitro human muscle preparation suitable for metabolic studies. J Clin Invest 82 (1988) 486-494
-
(1988)
J Clin Invest
, vol.82
, pp. 486-494
-
-
Dohm, G.L.1
Tapscott, E.B.2
Pories, W.J.3
Dabbs, D.J.4
Flickinger, E.G.5
Meelheim, T.F.6
Atkinson, S.M.7
Elton, C.W.8
Caro, J.F.9
-
26
-
-
1542286874
-
Soy protein affects serum insulin and hepatic SREBP-1 mRNA and reduces fatty liver in rats
-
Ascencio C., Torres N., Isoard-Acosta F., Gómez-Pérez F.J., Hernández-Pando R., and Tovar A.R. Soy protein affects serum insulin and hepatic SREBP-1 mRNA and reduces fatty liver in rats. J Nutr 134 (2004) 522-529
-
(2004)
J Nutr
, vol.134
, pp. 522-529
-
-
Ascencio, C.1
Torres, N.2
Isoard-Acosta, F.3
Gómez-Pérez, F.J.4
Hernández-Pando, R.5
Tovar, A.R.6
-
27
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
28
-
-
0038445987
-
Cell signalling of the GLP-1 action in rat liver
-
Redondo A., Trigo V., Acitores A., Valverde I., and Villanueva-Peñacarrillo M.L. Cell signalling of the GLP-1 action in rat liver. Mol Cell Endocrinol 204 (2003) 43-50
-
(2003)
Mol Cell Endocrinol
, vol.204
, pp. 43-50
-
-
Redondo, A.1
Trigo, V.2
Acitores, A.3
Valverde, I.4
Villanueva-Peñacarrillo, M.L.5
-
29
-
-
0027184119
-
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1 (7-36)-amide receptor of insulin-secreting β-cells
-
Göke R., Fehmann H.C., Linn T., Schmidt H., Krause M., and Eng J. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1 (7-36)-amide receptor of insulin-secreting β-cells. J Biol Chem 268 (1993) 19650-19655
-
(1993)
J Biol Chem
, vol.268
, pp. 19650-19655
-
-
Göke, R.1
Fehmann, H.C.2
Linn, T.3
Schmidt, H.4
Krause, M.5
Eng, J.6
-
30
-
-
0032960834
-
Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 9-39
-
Edwards C.M., Todd J.F., Mahmoudi M., Wang Z., Wang R.M., and Ghatei M. Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 9-39. Diabetes 48 (1999) 86-93
-
(1999)
Diabetes
, vol.48
, pp. 86-93
-
-
Edwards, C.M.1
Todd, J.F.2
Mahmoudi, M.3
Wang, Z.4
Wang, R.M.5
Ghatei, M.6
-
31
-
-
0035434115
-
Glucose competence of the heptoportal vein sensor requires the presence of an activated glucagon-like peptide 1 receptor
-
Burcelin R., Da Costa A., Drucker D., and Thorens B. Glucose competence of the heptoportal vein sensor requires the presence of an activated glucagon-like peptide 1 receptor. Diabetes 50 (2001) 1720-1728
-
(2001)
Diabetes
, vol.50
, pp. 1720-1728
-
-
Burcelin, R.1
Da Costa, A.2
Drucker, D.3
Thorens, B.4
-
32
-
-
0027425034
-
Cloning and functional expression of the human islet GLP-1 receptor: demonstration that exendin-4 is an agonist and exendin(9-39) an antagonist of the receptor
-
Thorens B., Porret A., Bühler L., Deng S.P., Morel P., and Widmann C. Cloning and functional expression of the human islet GLP-1 receptor: demonstration that exendin-4 is an agonist and exendin(9-39) an antagonist of the receptor. Diabetes 42 (1993) 1678-1682
-
(1993)
Diabetes
, vol.42
, pp. 1678-1682
-
-
Thorens, B.1
Porret, A.2
Bühler, L.3
Deng, S.P.4
Morel, P.5
Widmann, C.6
-
33
-
-
0036496551
-
Exendin-4 increases insulin sensitivity via a PI-3-Kinase-dependent mechanism: contrasting effects of GLP-1
-
Idris I., Patiag D., Gray S., and Donelly R. Exendin-4 increases insulin sensitivity via a PI-3-Kinase-dependent mechanism: contrasting effects of GLP-1. Biochem Pharmacol 63 (2002) 993-996
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 993-996
-
-
Idris, I.1
Patiag, D.2
Gray, S.3
Donelly, R.4
-
34
-
-
33644688228
-
GLP-1 signalling and effects on glucose metabolism in myocytes from type 2 diabetic patients
-
González N., Sancho V., Martín-Duce A., Tornero-Esteban P., Valverde I., Malaisse W.J., and Villanueva-Peñacarrillo M.L. GLP-1 signalling and effects on glucose metabolism in myocytes from type 2 diabetic patients. Int J Mol Med 16 (2005) 747-752
-
(2005)
Int J Mol Med
, vol.16
, pp. 747-752
-
-
González, N.1
Sancho, V.2
Martín-Duce, A.3
Tornero-Esteban, P.4
Valverde, I.5
Malaisse, W.J.6
Villanueva-Peñacarrillo, M.L.7
-
35
-
-
34748898831
-
Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats
-
Vahl T.P., Tauchi M., Durler T.S., Elfers E.E., Fernandes T.M., Bitner R.D., Ellis K.S., Woods S.C., Seeley R.J., Herman J.P., and D'Alessio D.A. Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. Endocrinology 148 (2007) 4965-4973
-
(2007)
Endocrinology
, vol.148
, pp. 4965-4973
-
-
Vahl, T.P.1
Tauchi, M.2
Durler, T.S.3
Elfers, E.E.4
Fernandes, T.M.5
Bitner, R.D.6
Ellis, K.S.7
Woods, S.C.8
Seeley, R.J.9
Herman, J.P.10
D'Alessio, D.A.11
|