Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controls

Journal of Clinical Virology

Volumn 44, Issue 2, 2009, Pages 164-166

  Bluemn, Eric G ^a   Paulson, Kelly G ^b   Higgins, Erin E ^b   Sun, Yu ^a   Nghiem, Paul ^b   Nelson, Peter S ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

MCPyV; MCV; Merkel cell; Polyomavirus; Prostate cancer

Indexed keywords

ARTICLE; CARCINOGENESIS; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; MALE; MERKEL CELL POLYOMAVIRUS; MERKEL CELL TUMOR; POLYOMA VIRUS; PRIORITY JOURNAL; PROSTATE CANCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS DETECTION; VIRUS TRANSMISSION;

ANTIGENS, POLYOMAVIRUS TRANSFORMING; HUMANS; MALE; POLYOMAVIRUS; POLYOMAVIRUS INFECTIONS; PROSTATE; PROSTATIC NEOPLASMS; RNA, MESSENGER; RNA, VIRAL; TUMOR VIRUS INFECTIONS;

EID: 59849104443     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2008.11.008     Document Type: Article

References (14)

1. Nelson W.G., De Marzo A.M., and Isaacs W.B. Prostate cancer. N Engl J Med 349 July (4) (2003) 366-381
2. Urisman A., Molinaro R.J., Fischer N., Plummer S.J., Casey G., Klein E.A., et al. Identification of a novel gammaretrovirus in prostate tumors of patients homozygous for R462q rnasel variant. PLoS Pathog 2 March (3) (2006) e25
3. Dong B., Kim S., Hong S., Das Gupta J., Malathi K., Klein E.A., et al. An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors. Proc Natl Acad Sci USA 104 January (5) (2007) 1655-1660
4. Fischer N., Hellwinkel O., Schulz C., Chun F.K., Huland H., Aepfelbacher M., et al. Prevalence of human gammaretrovirus Xmrv in sporadic prostate cancer. J Clin Virol 43 November (3) (2008) 277-283
5. Das D., Wojno K., and Imperiale M.J. Bk virus as a cofactor in the etiology of prostate cancer in its early stages. J Virol 82 March (6) (2008) 2705-2714
6. Aus G., Robinson D., Rosell J., Sandblom G., and Varenhorst E. Survival in prostate carcinoma-outcomes from a prospective, population-based cohort of 8887 men with up to 15 years of follow-up: results from three countries in the population-based national prostate cancer registry of Sweden. Cancer 103 March (5) (2005) 943-951
7. Heath M., Jaimes N., Lemos B., Mostaghimi A., Wang L.C., Penas P.F., et al. Clinical characteristics of merkel cell carcinoma at diagnosis in 195 patients: the aeiou features. J Am Acad Dermatol 58 March (3) (2008) 375-381
8. Agelli M., and Clegg L.X. Epidemiology of primary merkel cell carcinoma in the United States. J Am Acad Dermatol 49 November (5) (2003) 832-841
9. Feng H., Shuda M., Chang Y., and Moore P.S. Clonal integration of a polyomavirus in human merkel cell carcinoma. Science 319 February (5866) (2008) 1096-1100
10. Garneski K.M., Warcola A.H., Feng Q., Kiviat N.B., Leonard J.H., and Nghiem P. Merkel cell polyomavirus is more frequently present in North American than Australian Merkel cell carcinoma tumors. J Invest Dermatol 129 (2009) 246-248
11. Becker J.C., Houben R., Ugurel S., Trefzer U., Pfohler C., and Schrama D. Mc polyomavirus is frequently present in Merkel cell carcinoma of European patients. J Invest Dermatol 129 (2009) 248-250
12. Shuda M., Feng H., Kwun H.J., Rosen S.T., Gjoerup O., Moore P.S., et al. T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus. Proc Natl Acad Sci USA 105 October (42) (2008) 16272-16277
13. True L., Coleman I., Hawley S., Huang C.Y., Gifford D., Coleman R., et al. A molecular correlate to the gleason grading system for prostate adenocarcinoma. Proc Natl Acad Sci USA 103 July (29) (2006) 10991-10996
14. Mostaghel E.A., Page S.T., Lin D.W., Fazli L., Coleman I.M., True L.D., et al. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res 67 May (10) (2007) 5033-5041