Lack of laminin γ1 in embryonic stem cell-derived cardiomyocytes causes inhomogeneous electrical spreading despite intact differentiation and function

Stem Cells

Volumn 27, Issue 1, 2009, Pages 88-99

  Malan, Daniela ^a,b   Reppel, Michael ^c   Dobrowolski, Radoslaw ^a   Roell, Wilhelm ^a   Smyth, Neil ^c,d   Hescheler, Juergen ^c   Paulsson, Mats ^c   Bloch, Wilhelm ^b   Fleischmann, Bernd K ^a  

^a UNIVERSITY OF BONN   (Germany)

^b GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Embryonic stem derived cardiomyocytes; Extracellular matrix; Hormonal regulation; Laminin 1

Indexed keywords

INTEGRIN; LAMININ GAMMA1; CADHERIN; LAMININ;

ARTICLE; BASEMENT MEMBRANE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; ELECTRIC ACTIVITY; EMBRYONIC STEM CELL; EXTRACELLULAR MATRIX; HEART MUSCLE CELL; HORMONAL REGULATION; PROTEIN EXPRESSION; SARCOMERE; SINUS NODE; ACTION POTENTIAL; ANIMAL; CYTOLOGY; CYTOSKELETON; ELECTRIC CONDUCTIVITY; METABOLISM; MOUSE; UPREGULATION;

ACTION POTENTIALS; ANIMALS; BASEMENT MEMBRANE; CADHERINS; CELL DIFFERENTIATION; CYTOSKELETON; ELECTRIC CONDUCTIVITY; EMBRYONIC STEM CELLS; EXTRACELLULAR MATRIX; INTEGRINS; LAMININ; MICE; MYOCYTES, CARDIAC; UP-REGULATION;

EID: 59849091056     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2008-0335     Document Type: Article

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