The need for realism in reproductive toxicity testing

Alternatives to Laboratory Animals

Volumn 36, Issue 6, 2008, Pages 717-

  Bremer, Susanne ^a  

^a JOINT RESEARCH CENTRE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

THALIDOMIDE;

ANIMAL USE; EMBRYO DEVELOPMENT; NONHUMAN; NOTE; PHENOTYPE; PRACTICE GUIDELINE; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; TERATOGENICITY; TOXICITY TESTING;

EID: 59849089046     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290803600617     Document Type: Note

References (4)

1. Moxon, M. (2008). Developmental and reproductive toxicity testing: a potted history. Lab Animal Europe 8(3), 3.
2. Janer, G., Hakkert, B.C., Slob, W., Vermeire, T. &Piersma, A.H. (2007). A retrospective analysis of the two-generation study: what is the added value of the second generation? Reproductive Toxicology 24, 97-102.
3. Anon. (2008). DRAFT Extended One-Generation Reproductive Toxicity TEST GUIDELINE, 37pp. Paris, France: OECD. Available at: http://www.oecd.org/ dataoecd/22/20/40899803.pdf (Accessed 28.07.08).
4. Janer, G., Slob, W., Hakkert, B.C., Vermeire, T. &Piersma, A.H. (2008). Retrospective analysis of developmental toxicity studies in rat and rabbit: what is the added value of the rabbit as an additional test species? Regulatory Toxicology &Pharmacology 50, 206-217.