Vitamin D: Current status and perspectives

Clinical Chemistry and Laboratory Medicine

Volumn 47, Issue 2, 2009, Pages 120-127

  Cavalier, Etienne ^a   Delanaye, Pierre ^a   Chapelle, Jean Paul ^a   Souberbielle, Jean Claude ^b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Deficiency; New insights; Non skeletal actions; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; CALCIUM; ERGOCALCIFEROL; VITAMIN D; VITAMIN D RECEPTOR;

AUTOIMMUNE DISEASE; AUTOIMMUNITY; BONE MINERALIZATION; CANCER PREVENTION; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CONFERENCE PAPER; COST BENEFIT ANALYSIS; DIABETES CONTROL; DRUG EFFECT; DRUG MECHANISM; FRAGILITY FRACTURE; HUMAN; HYPERCALCEMIA; IMMUNOMODULATION; INFECTION; INFECTION PREVENTION; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY CALCIFICATION; LACTATION; NON INSULIN DEPENDENT DIABETES MELLITUS; OSTEOLYSIS; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECOMMENDED DRUG DOSE; UNSPECIFIED SIDE EFFECT; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN D METABOLISM; VITAMIN SUPPLEMENTATION;

DIETARY SUPPLEMENTS; HUMANS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 59849083259     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2009.036     Document Type: Conference Paper

References (89)

1. Ide M. The bios of Wildiers and the cultivation of yeast. J Biol Chem 1921;XLVI(3):521-3.
2. Funk C. The etiology of deficiency disease. J State Med 1912;XX:341-68.
3. Funk C, Dubin HE. The vitamins of yeast and their role in animal nutrition. Proc Soc Exp Biol 1921;19:15.
4. Heaton TB. On the Vitamin D. Biochem J 1922;16:800-8.
5. Hess AF. The prevention and cure of rickets by sunlight. Am J Public Health (NY) 1922;12:104-7.
6. Hess AF, Weinstock M, Heelman FD. The antirachitic value of irradiated phytosterol and cholesterol. J Biol Chem 1925;63:305-9.
7. Rosenheim O, Webster TA. Further observations on the photo-chemical formation of vitamin D. J Soc Chem Ind 1926;45:932.
8. Rosenheim O, Webster TA. The parent substance of vitamin D. Biochem J 1927;21:389-97.
9. Windaus A, Bock F. Über das Provitamin aus dem Sterin der Schweineschwarte. Z Physiol Chem 1937;245:168-70.
10. Houillier P, Nicolet-Barousse L, Maruani G, Paillard M. What keeps serum calcium levels stable? Joint Bone Spine 2003;70:407-13.
11. Souberbielle JC, Friedlander G, Kahan A, Cormier C. Evaluating vitamin D status. Implications for preventing and managing osteoporosis and other chronic diseases. Joint Bone Spine 2006;73:249-53.
12. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81.
13. Heaney RP. Vitamin D: how much do we need, and how much is too much? Osteoporos Int 2000;11:553-5.
14. Hollis BW. Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D. J Nutr 2005;135:317-22.
15. Zittermann A. Vitamin D in preventive medicine: are we ignoring the evidence? Br J Nutr 2003;89:552-72.
16. Holick MF. Too little vitamin D in premenopausal women: why should we care? Am J Clin Nutr 2002;76:3-4.
17. Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 2001;22:477-501.
18. Lips P, Chapuy MC, Dawson-Hughes B, Pols HA, Holick MF. An international comparison of serum 25-hydroxyvitamin D measurements. Osteoporos Int 1999;9:394-7.
19. Binkley N, Krueger D, Cowgill CS, Plum L, Lake E, Hansen KE, et al. Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab 2004;89:3152-7.
20. Hollis BW. The determination of circulating 25-hydroxyvitamin D: no easy task [editorial]. J Clin Endocrinol Metab 2004;89:3149-51.
21. Cavalier E, Wallace AM, Knox S, Mistretta VI, Cormier C, Souberbielle JC. Serum vitamin D measurement may not reflect what you give to your patients. J Bone Miner Res 2008;23:1864-5.
22. Dawson-Hughes B, Harris SS, Dallal GE. Plasma calcidiol, season, and serum parathyroid hormone concentrations in healthy elderly men and women. Am J Clin Nutr 1997;65:67-71.
23. Malabanan A, Veronikis IE, Holick MF. Redefining vitamin D insufficiency. Lancet 1998;351:805-6.
24. Aloia JF, Talwar SA, Pollack S, Feuerman M, Yeh JK. Optimal vitamin D status and serum parathyroid hormone concentrations in African American women. Am J Clin Nutr 2006;84:602-9.
25. Sahota O, Mundey MK, San P, Godber IM, Hosking DJ. Vitamin D insufficiency and the blunted PTH response in established osteoporosis: the role of magnesium deficiency. Osteoporos Int 2006;17:1013-21.
26. Heaney RP, Dowell MS, Hale CA, Bendich A. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr 2003;22:142-6.
27. Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. J Am Med Assoc 2006;296:2832-8.
28. Garland CF, Gorham ED, Mohr SB, Grant WB, Giovannucci EL, Lipkin M, et al. Vitamin D and prevention of breast cancer: pooled analysis. J Steroid Biochem Mol Biol 2007;103:708-11.
29. Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, et al. Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am J Prev Med 2007;32:210-6.
30. Forman JP, Giovannucci E, Holmes MD, Bischoff-Ferrari HA, Tworoger SS, Willet WC, et al. Plasma 25-hydroxyvitamin D levels and risk of incident hypertension. Hypertension 2007;49:1063-9.
31. Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. J Am Med Assoc 2005;293:2257-64.
32. Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY et al. Effect of vitamin D on falls: a meta-analysis. J Am Med Assoc 2004;291:1999-2006.
33. Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, Heaney RP. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr 2007;85:1586-91.
34. Krall EA, Wehler C, Garcia RI, Harris SS, Dawson-Hughes B. Calcium and vitamin D supplements reduce tooth loss in the elderly. Am J Med 2001;111:452-6.
35. Baynes KC, Boucher BJ, Feskens EJ, Kromhout D. Vitamin D, glucose tolerance and insulinaemia in elderly men. Diabetologia 1997;40:344-7.
36. Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C. Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. J Clin Endocrinol Metab 2001;86:1633-7.
37. Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R. Estimates of optimal vitamin D status. Osteoporos Int 2005;16:713-6.
38. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 2004;80:1678S-88S.
39. Webb AR. Who, what, where and when - influences on cutaneous vitamin D synthesis. Prog Biophys Mol Biol 2006;92:17-25.
40. Institute of Medicine. Dietary reference intakes: calcium, phosphorus, magnesium, vitamin D, fluoride. Washington DC, USA: National Academy Press, 1997.
41. Chambellan-Tison C, Horen B, Plat-Wilson G, Moulin P, Claudet I. [Severe hypercalcemia due to vitamin D intoxication]. Arch Pediatr 2007;14:1328-32 [in French with English abstract].
42. Reginster JY. The high prevalence of inadequate serum vitamin D levels and implications for bone health. Curr Med Res Opin 2005;21:579-86.
43. Favus MJ, Bushinsky DA, Leman J Jr. Regulation of calcium, magnesium, and phosphate metabolism. In: Primer on the metabolic bone diseases and disorders of mineral metabolism, 6th ed. Washington DC, USA: The American Society of Bone and Mineral Research, 2006:76-83.
44. Walters JR, Balesaria S, Khair U, Sangha S, Banks L, Berry JL. The effects of vitamin D metabolites on expression of genes for calcium transporters in human duodenum. J Steroid Biochem Mol Biol 2007;103:509-12.
45. Benn BS, Ajibade D, Porta A, Dhawan P, Hediger M, Peng JB, et al. Active intestinal calcium transport in the absence of TRPV6 and calbindin-D9k. Endocrinology 2008;149:3196-205.
46. Basha B, Rao DS, Han ZH, Parfitt AM. Osteomalacia due to vitamin D depletion: a neglected consequence of intestinal malabsorption. Am J Med 2000;108:296-300.
47. Takahashi N, Udagawa N, Takami M, Suda T. Cells of bone: osteoclast generation. In: Bilezikian JP, Raisz LG, Rodan GA, editors. Principles of bone biology. New York, NY, USA: Academic Press, 2005:109-26.
48. Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999;20:345-57.
49. Reginster JY. Calcium and vitamin D for osteoporotic fracture risk. Lancet 2007;370:632-4.
50. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Dawson-Hughes B. Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults. Am J Med 2004;116:634-9.
51. Rizzoli R, Boonen S, Brandi ML, Burlet N, Delmas P, Reginster JY. The role of calcium and vitamin D in the management of osteoporosis. Bone 2008;42:246-9.
52. Hypponen E, Laara E, Reunanen A, Jarvelin MR, Virtanen SM. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 2001;358:1500-3.
53. Pittas AG, Dawson-Hughes B, Li T, Van Dam RM, Willett WC, Manson JE, et al. Vitamin D and calcium intake in relation to type 2 diabetes in women. Diabetes Care 2006;29:650-6.
54. Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006;311:1770-3.
55. Smolders J, Damoiseaux J, Menheere P, Hupperts R. Vitamin D as an immune modulator in multiple sclerosis, a review. J Neuroimmunol 2008;194:7-17.
56. Merlino LA, Curtis J, Mikuls TR, Cerhan JR, Criswell LA, Saag KG. Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study. Arthritis Rheum 2004;50:72-7.
57. Garland FC, Garland CF, Gorham ED, Young JF. Geographic variation in breast cancer mortality in the United States: a hypothesis involving exposure to solar radiation. Prev Med 1990;19:614-22.
58. Lefkowitz ES, Garland CF. Sunlight, vitamin D, and ovarian cancer mortality rates in US women. Int J Epidemiol 1994;23:1133-6.
59. Garland CF, Garland FC. Do sunlight and vitamin D reduce the likelihood of colon cancer? Int J Epidemiol 1980;9:227-31.
60. Schwartz GG, Hulka BS. Is vitamin D deficiency a risk factor for prostate cancer? (hypothesis). Anticancer Res 1990;10:1307-11.
61. Giovannucci E. Vitamin D and cancer incidence in the Harvard cohorts. Ann Epidemiol 2008;Feb 19. [Epub ahead of print].
62. Giovannucci E. The epidemiology of vitamin D and cancer incidence and mortality: a review (United States). Cancer Causes Control 2005;16:83-95.
63. Martins D, Wolf M, Pan D, Zadshir A, Tareen N, Thadhani R, et al. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Arch Intern Med 2007;167:1159-65.
64. Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation 2008;117:503-11.
65. Li YC, Kong J, Wei M, Chen ZF, Liu SQ, Cao LP. 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest 2002;110:229-38.
66. O'Connell TD, Berry JE, Jarvis AK, Somerman MJ, Simpson RU. 1,25-Dihydroxyvitamin D3 regulation of cardiac myocyte proliferation and hypertrophy. Am J Physiol 1997;272:H1751-8.
67. Kristal-Boneh E, Froom P, Harari G, Ribak J. Association of calcitriol and blood pressure in normotensive men. Hypertension 1997;30:1289-94.
68. Lind L, Hanni A, Lithell H, Hvarfner A, Sorensen OH, Ljunghall S. Vitamin D is related to blood pressure and other cardiovascular risk factors in middle-aged men. Am J Hypertens 1995;8:894-901.
69. Watson KE, Abrolat ML, Malone LL, Hoeg JM, Doherty T, Detrano R, et al. Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation 1997;96:1755-60.
70. Scragg R, Jackson R, Holdaway IM, Lim T, Beaglehole R. Myocardial infarction is inversely associated with plasma 25-hydroxyvitamin D3 levels: a community-based study. Int J Epidemiol 1990;19:559-63.
71. Poole KE, Loveridge N, Barker PJ, Halsall DJ, Rose C, Reeve J, et al. Reduced vitamin D in acute stroke. Stroke 2006;37:243-5.
72. Zittermann A, Schleithoff SS, Tenderich G, Berthold HK, Korfer R, Stehle P. Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure? J Am Coll Cardiol 2003;41:105-12.
73. Dawodu A, Agarwal M, Hossain M, Kochiyil J, Zayed R. Hypovitaminosis D and vitamin D deficiency in exclusively breast-feeding infants and their mothers in summer: a justification for vitamin D supplementation of breast-feeding infants. J Pediatr 2003;142:169-73.
74. Cavalier E, Delanaye P, Morreale A, Carlisi A, Mourad I, Chapelle JP et al. La carence en vitamine D chez les femmes enceintes en région liégeoise: un problème méconnu. Rev Med Liege 2008;74:87-91.
75. Javaid MK, Crozier SR, Harvey NC, Gale CR, Dennison EM, Boucher BJ, et al. Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet 2006;367:36-43.
76. Dijkstra SH, van Beek A, Janssen JW, de Vleeschouwer LH, Huysman WA, van den Akker EL. High prevalence of vitamin D deficiency in newborn infants of high-risk mothers. Arch Dis Child 2007;92:750-3.
77. Pawley N, Bishop NJ. Prenatal and infant predictors of bone health: the influence of vitamin D. Am J Clin Nutr 2004;80:1748S-51S.
78. Bodnar LM, Catov JM, Simhan HN, Holick MF, Powers RW, Roberts JM. Maternal vitamin D deficiency increases the risk of preeclampsia. J Clin Endocrinol Metab 2007;92:3517-22.
79. Camargo CA Jr, Rifas-Shiman SL, Litonjua AA, Rich-Edwards JW, Weiss ST, Gold DR, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr 2007;85:788-95.
80. Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol 2007;120:1031-5.
81. McGrath JJ, Welham JL. Season of birth and schizophrenia: a systematic review and meta-analysis of data from the Southern Hemisphere. Schizophr Res 1999;35:237-42.
82. Altschuler EL. Low maternal vitamin D and schizophrenia in offspring. Lancet 2001;358:1464.
83. Cannell JJ. Autism and vitamin D. Med Hypotheses 2008;70:750-9.
84. Hollis BW. Vitamin D requirement during pregnancy and lactation. J Bone Miner Res 2007;22(Suppl 2):V39-V44.
85. Diamond J. Evolutionary biology: geography and skin colour. Nature 2005;435:283-4.
86. Jablonski NG, Chaplin G. The evolution of human skin coloration. J Hum Evol 2000;39:57-106.
87. Jablonski NG, Chaplin G. Skin deep. Sci Am 2002;287:74-81.
88. Relethford JH. Hemispheric difference in human skin color. Am J Phys Anthropol 1997;104:449-57.
89. Vieth R. What is the optimal vitamin D status for health? Prog Biophys Mol Biol 2006;92:26-32.