메뉴 건너뛰기




Volumn 94, Issue 2, 2009, Pages 639-644

Influence of the exon 3-deleted/full-length growth hormone (GH) receptor polymorphism on the response to Gh replacement therapy in adults with severe GH deficiency

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RECEPTOR; SOMATOMEDIN C;

EID: 59749098582     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-0323     Document Type: Article
Times cited : (33)

References (40)
  • 1
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon F, Cuneo RC, Hesp R, Sonksen PH 1989 The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 321:1797-1803
    • (1989) N Engl J Med , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Hesp, R.3    Sonksen, P.H.4
  • 4
    • 0035742620 scopus 로고    scopus 로고
    • Biochemical markers of individual response to growth hormone replacement in adults
    • Monson JP 2001 Biochemical markers of individual response to growth hormone replacement in adults. Horm Res 55(Suppl 2):49-54
    • (2001) Horm Res , vol.55 , Issue.SUPPL. 2 , pp. 49-54
    • Monson, J.P.1
  • 5
    • 17344367528 scopus 로고    scopus 로고
    • Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: A critical appraisal
    • Gibney J, Johannsson G 2004 Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: a critical appraisal. Horm Res 62(Suppl 1):66-72
    • (2004) Horm Res , vol.62 , Issue.SUPPL. 1 , pp. 66-72
    • Gibney, J.1    Johannsson, G.2
  • 6
    • 0029922124 scopus 로고    scopus 로고
    • The individual responsiveness to growth hormone (GH) treatment in GH-deficient adults is dependent on the level of GH-binding protein, body mass index, age, and gender
    • Johannsson G, Bjarnason R, Bramnert M, Carlsson LM, Degerblad M, Manhem P, Rośen T, Thorén M, Bengtsson BA 1996 The individual responsiveness to growth hormone (GH) treatment in GH-deficient adults is dependent on the level of GH-binding protein, body mass index, age, and gender. J Clin Endocrinol Metab 81:1575-1581
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1575-1581
    • Johannsson, G.1    Bjarnason, R.2    Bramnert, M.3    Carlsson, L.M.4    Degerblad, M.5    Manhem, P.6    Rośen, T.7    Thorén, M.8    Bengtsson, B.A.9
  • 8
    • 0033323802 scopus 로고    scopus 로고
    • The effects of treatment and the individual responsiveness to growth hormone (GH) replacement therapy in 665 GH-deficient adults. KIMS Study Group and the KIMS International Board
    • Bengtsson BA, Abs R, Bennmarker H, Monson JP, Feldt-Rasmussen U, Hernberg-Stahl E, Westberg B, Wilton P, Wüster C 1999 The effects of treatment and the individual responsiveness to growth hormone (GH) replacement therapy in 665 GH-deficient adults. KIMS Study Group and the KIMS International Board. J Clin Endocrinol Metab 84:3929-3935
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3929-3935
    • Bengtsson, B.A.1    Abs, R.2    Bennmarker, H.3    Monson, J.P.4    Feldt-Rasmussen, U.5    Hernberg-Stahl, E.6    Westberg, B.7    Wilton, P.8    Wüster, C.9
  • 10
    • 0033343113 scopus 로고    scopus 로고
    • Route of estrogen administration helps to determine growth hormone (GH) replacement dose in GH-deficient adults
    • Cook DM, Ludlam WH, Cook MB 1999 Route of estrogen administration helps to determine growth hormone (GH) replacement dose in GH-deficient adults. J Clin Endocrinol Metab 84:3956-3960
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3956-3960
    • Cook, D.M.1    Ludlam, W.H.2    Cook, M.B.3
  • 11
    • 0034452986 scopus 로고    scopus 로고
    • Gender difference in insulin-like growth factor I response to growth hormone (GH) treatment in GH-deficient adults: Role of sex hormone replacement
    • Span JP, Pieters GF, Sweep CG, Hermus AR, Smals AG 2000 Gender difference in insulin-like growth factor I response to growth hormone (GH) treatment in GH-deficient adults: role of sex hormone replacement. J Clin Endocrinol Metab 85:1121-1125
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1121-1125
    • Span, J.P.1    Pieters, G.F.2    Sweep, C.G.3    Hermus, A.R.4    Smals, A.G.5
  • 12
    • 3042780191 scopus 로고    scopus 로고
    • A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone
    • Dos Santos C, Essioux L, Teinturier C, Tauber M, Goffin V, Bougneres P 2004 A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone. Nat Genet 36:720-724
    • (2004) Nat Genet , vol.36 , pp. 720-724
    • Dos Santos, C.1    Essioux, L.2    Teinturier, C.3    Tauber, M.4    Goffin, V.5    Bougneres, P.6
  • 13
    • 0034705518 scopus 로고    scopus 로고
    • Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution
    • Pantel J, Machinis K, Sobrier ML, Duquesnoy P, Goossens M, Amselem S 2000 Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution. J Biol Chem 275:18664-18669
    • (2000) J Biol Chem , vol.275 , pp. 18664-18669
    • Pantel, J.1    Machinis, K.2    Sobrier, M.L.3    Duquesnoy, P.4    Goossens, M.5    Amselem, S.6
  • 14
    • 33644828425 scopus 로고    scopus 로고
    • Growth hormone (GH) pharmacogenetics: Influence of GH receptor exon 3 retention or deletion on first-year growth response and final height in patients with severe GH deficiency
    • Jorge AA, Marchisotti FG, Montenegro LR, Carvalho LR, Mendonca BB, Arnhold IJ 2006 Growth hormone (GH) pharmacogenetics: influence of GH receptor exon 3 retention or deletion on first-year growth response and final height in patients with severe GH deficiency. J Clin Endocrinol Metab 91:1076-1080
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1076-1080
    • Jorge, A.A.1    Marchisotti, F.G.2    Montenegro, L.R.3    Carvalho, L.R.4    Mendonca, B.B.5    Arnhold, I.J.6
  • 16
    • 34548039943 scopus 로고    scopus 로고
    • Tauber M, Ester W, Auriol F, Molinas C, Fauvel J, Caliebe J, Nugent T, Fryklund L, Ranke MB, Savage MO, Clark AJ, Johnston LB, Hokken-Koelega AC; NESTEG Ggroup 2007 GH responsiveness in a large multinational cohort of SGA children with short stature (NESTEGG) is related to the exon 3 GHR polymorphism. Clin Endocrinol (Oxf) 67:457-461
    • Tauber M, Ester W, Auriol F, Molinas C, Fauvel J, Caliebe J, Nugent T, Fryklund L, Ranke MB, Savage MO, Clark AJ, Johnston LB, Hokken-Koelega AC; NESTEG Ggroup 2007 GH responsiveness in a large multinational cohort of SGA children with short stature (NESTEGG) is related to the exon 3 GHR polymorphism. Clin Endocrinol (Oxf) 67:457-461
  • 17
    • 33644831885 scopus 로고    scopus 로고
    • Common polymorphisms of the growth hormone (GH) receptor do not correlate with the growth response to exogenous recombinant human GH in GH-deficient children
    • Pilotta A, Mella P, Filisetti M, Felappi B, Prandi E, Parrinello G, Notarangelo LD, Buzi F 2006 Common polymorphisms of the growth hormone (GH) receptor do not correlate with the growth response to exogenous recombinant human GH in GH-deficient children. J Clin Endocrinol Metab 91:1178-1180
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1178-1180
    • Pilotta, A.1    Mella, P.2    Filisetti, M.3    Felappi, B.4    Prandi, E.5    Parrinello, G.6    Notarangelo, L.D.7    Buzi, F.8
  • 18
    • 33749545489 scopus 로고    scopus 로고
    • The growth response to growth hormone (GH) treatment in children with isolated GH deficiency is independent of the presence of the exon 3-minus isoform of the GH receptor
    • Blum WF, Machinis K, Shavrikova EP, Keller A, Stobbe H, Pfaeffle RW, Amselem S 2006 The growth response to growth hormone (GH) treatment in children with isolated GH deficiency is independent of the presence of the exon 3-minus isoform of the GH receptor. J Clin Endocrinol Metab 91:4171-4174
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4171-4174
    • Blum, W.F.1    Machinis, K.2    Shavrikova, E.P.3    Keller, A.4    Stobbe, H.5    Pfaeffle, R.W.6    Amselem, S.7
  • 19
    • 33748748058 scopus 로고    scopus 로고
    • Carrascosa A, Esteban C, Espadero R, Fernández-Cancio M, Andaluz P, Clemente M, Audí L, Wollmann H, Fryklund L, Parodi L; Spanish SGA Study Group 2006 The d3/fl-growth hormone (GH) receptor polymorphism does not influence the effect of GH treatment (66 microg/kg per day) or the spontaneous growth in short non-GH-deficient small-for-gestational-age children: results from a two-year controlled prospective study in 170 Spanish patients. J Clin Endocrinol Metab 91:3281-3286
    • Carrascosa A, Esteban C, Espadero R, Fernández-Cancio M, Andaluz P, Clemente M, Audí L, Wollmann H, Fryklund L, Parodi L; Spanish SGA Study Group 2006 The d3/fl-growth hormone (GH) receptor polymorphism does not influence the effect of GH treatment (66 microg/kg per day) or the spontaneous growth in short non-GH-deficient small-for-gestational-age children: results from a two-year controlled prospective study in 170 Spanish patients. J Clin Endocrinol Metab 91:3281-3286
  • 20
    • 38149004249 scopus 로고    scopus 로고
    • Growth hormone (GH) dose, but not exon 3-deleted/full-length GH receptor polymorphism genotypes, influences growth response to two-year GH therapy in short small-for- gestational-age children
    • Carrascosa A, Audi L, Steban C, Fernández-Cancio M, Andaluz P, Gussinyé M, Clemente M, Yeste D, Albisu MA 2008 Growth hormone (GH) dose, but not exon 3-deleted/full-length GH receptor polymorphism genotypes, influences growth response to two-year GH therapy in short small-for- gestational-age children. J Clin Endocrinol Metab 93:147-153
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 147-153
    • Carrascosa, A.1    Audi, L.2    Steban, C.3    Fernández-Cancio, M.4    Andaluz, P.5    Gussinyé, M.6    Clemente, M.7    Yeste, D.8    Albisu, M.A.9
  • 21
    • 40849142096 scopus 로고    scopus 로고
    • The exon 3-deleted/ full-length growth hormone receptor polymorphism did not influence growth response to growth hormone therapy over two years in prepubertal short children born at term with adequate weight and length for gestational age
    • Carrascosa A, Audi L, Fernández-Cancio M, Esteban, C, Andaluz, P, Vilaró, E, Clemente M, Yeste D, Albisu MA, Gussinyé M 2008 The exon 3-deleted/ full-length growth hormone receptor polymorphism did not influence growth response to growth hormone therapy over two years in prepubertal short children born at term with adequate weight and length for gestational age. J Clin Endocrinol Metab 93:764-770
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 764-770
    • Carrascosa, A.1    Audi, L.2    Fernández-Cancio, M.3    Esteban, C.4    Andaluz, P.5    Vilaró, E.6    Clemente, M.7    Yeste, D.8    Albisu, M.A.9    Gussinyé, M.10
  • 22
    • 0027935871 scopus 로고
    • Serum insulin-like growth factor I in a random population sample of men and women: Relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid and osteocalcin
    • Landin-Wilhelmsen K, Wilhelmsen L, Lappas G, Rosén T, Lindstedt G, Lundberg PA, Bengtsson BA 1994 Serum insulin-like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid and osteocalcin. Clin Endocrinol (Oxf) 41:351-357
    • (1994) Clin Endocrinol (Oxf) , vol.41 , pp. 351-357
    • Landin-Wilhelmsen, K.1    Wilhelmsen, L.2    Lappas, G.3    Rosén, T.4    Lindstedt, G.5    Lundberg, P.A.6    Bengtsson, B.A.7
  • 23
    • 0030744020 scopus 로고    scopus 로고
    • Insulin-like growth hormone-deficient adults: Relationship to population-based normal values, body composition and insulin tolerance test
    • Svensson J, Johannsson G, Bengtsson BA 1997 Insulin-like growth hormone-deficient adults: relationship to population-based normal values, body composition and insulin tolerance test. Clin Endocrinol (Oxf) 46:579-586
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 579-586
    • Svensson, J.1    Johannsson, G.2    Bengtsson, B.A.3
  • 24
    • 0019310130 scopus 로고
    • Body composition. Prediction of normal body potassium, body water and body fat in adults on the basis of body height, body weight and age
    • Bruce A, Andersson M, Arvidsson B, Isaksson B 1980 Body composition. Prediction of normal body potassium, body water and body fat in adults on the basis of body height, body weight and age. Scand J Clin Lab Invest 40:461-473
    • (1980) Scand J Clin Lab Invest , vol.40 , pp. 461-473
    • Bruce, A.1    Andersson, M.2    Arvidsson, B.3    Isaksson, B.4
  • 25
    • 33845504692 scopus 로고    scopus 로고
    • Audí L, Esteban C, Carrascosa A, Espadero R, Pérez-Arroyo A, Arjona R, Clemente M, Wollmann H, Fryklund L, Parodi LA; Spanish SGA Study Group 2006 Exon 3-deleted/full-length growth hormone receptor polymorphism genotype frequencies in Spanish short small-for- gestational-age (SGA) children and adolescents (n = 247) and in an adult control population (n = 289) show increased fl/fl in short SGA. J Clin Endocrinol Metab 91:5038-5043
    • Audí L, Esteban C, Carrascosa A, Espadero R, Pérez-Arroyo A, Arjona R, Clemente M, Wollmann H, Fryklund L, Parodi LA; Spanish SGA Study Group 2006 Exon 3-deleted/full-length growth hormone receptor polymorphism genotype frequencies in Spanish short small-for- gestational-age (SGA) children and adolescents (n = 247) and in an adult control population (n = 289) show increased fl/fl in short SGA. J Clin Endocrinol Metab 91:5038-5043
  • 29
    • 0028997553 scopus 로고
    • Expression of exon 3-retaining and exon 3-excluding isoforms of the human growth hormone-receptor is regulated in an interindividual, rather than a tissue-specific, manner
    • Wickelgren RB, Landin KL, Ohlsson C, Carlsson LM 1995 Expression of exon 3-retaining and exon 3-excluding isoforms of the human growth hormone-receptor is regulated in an interindividual, rather than a tissue-specific, manner. J Clin Endocrinol Metab 80:2154-2157
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2154-2157
    • Wickelgren, R.B.1    Landin, K.L.2    Ohlsson, C.3    Carlsson, L.M.4
  • 30
    • 32544437508 scopus 로고    scopus 로고
    • The d3-growth hormone (GH) receptor polymorphism is associated with increased responsiveness to GH in Turner syndrome and short small-for-gestational-age children
    • Binder G, Baur F, Schweizer R, Ranke MB 2006 The d3-growth hormone (GH) receptor polymorphism is associated with increased responsiveness to GH in Turner syndrome and short small-for-gestational-age children. J Clin Endocrinol Metab 91:659-664
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 659-664
    • Binder, G.1    Baur, F.2    Schweizer, R.3    Ranke, M.B.4
  • 31
    • 40749100650 scopus 로고    scopus 로고
    • Homozygosity of the d3-growth hormone receptor polymorphism is associated with a high total effect of GH on growth and a low BMI in girls with Turner syndrome
    • Binder G, Trebar B, Baur F, Schweizer R, Ranke MB 2008 Homozygosity of the d3-growth hormone receptor polymorphism is associated with a high total effect of GH on growth and a low BMI in girls with Turner syndrome. Clin Endocrinol (Oxf) 68:567-572
    • (2008) Clin Endocrinol (Oxf) , vol.68 , pp. 567-572
    • Binder, G.1    Trebar, B.2    Baur, F.3    Schweizer, R.4    Ranke, M.B.5
  • 33
    • 0026044443 scopus 로고
    • Growth hormone regulation of insulin-like growth factor-I mRNA in rat adipose tissue and isolated rat adipocytes
    • Vikman K, Isgaard J, Eden S 1991 Growth hormone regulation of insulin-like growth factor-I mRNA in rat adipose tissue and isolated rat adipocytes. J Endocrinol 131:139-145
    • (1991) J Endocrinol , vol.131 , pp. 139-145
    • Vikman, K.1    Isgaard, J.2    Eden, S.3
  • 34
    • 0030724963 scopus 로고    scopus 로고
    • Individualized dose titration of growth hormone (GH) during GH replacement in hypopituitary adults
    • Johannsson G, Rosen T, Bengtsson BA 1997 Individualized dose titration of growth hormone (GH) during GH replacement in hypopituitary adults. Clin Endocrinol (Oxf) 47:571-581
    • (1997) Clin Endocrinol (Oxf) , vol.47 , pp. 571-581
    • Johannsson, G.1    Rosen, T.2    Bengtsson, B.A.3
  • 36
    • 0034043541 scopus 로고    scopus 로고
    • Pre-treatment IGF-I level is the major determinant of GH dosage in adult GH deficiency
    • Murray RD, Howell SJ, Lisset CA, Shalet SM 2000 Pre-treatment IGF-I level is the major determinant of GH dosage in adult GH deficiency. Clin Endocrinol (Oxf) 52:537-542
    • (2000) Clin Endocrinol (Oxf) , vol.52 , pp. 537-542
    • Murray, R.D.1    Howell, S.J.2    Lisset, C.A.3    Shalet, S.M.4
  • 37
    • 33847249410 scopus 로고    scopus 로고
    • Management of adult growth hormone deficiency
    • Johannsson G 2007 Management of adult growth hormone deficiency. Endocrinol Metab Clin North Am 36:203-220
    • (2007) Endocrinol Metab Clin North Am , vol.36 , pp. 203-220
    • Johannsson, G.1
  • 39
    • 13244275093 scopus 로고    scopus 로고
    • One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults
    • Boguszewski CL, Meister LH, Zaninelli DC, Radominski RB 2005 One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults. Eur J Endocrinol 152:67-75
    • (2005) Eur J Endocrinol , vol.152 , pp. 67-75
    • Boguszewski, C.L.1    Meister, L.H.2    Zaninelli, D.C.3    Radominski, R.B.4
  • 40
    • 34447123266 scopus 로고    scopus 로고
    • The presence of the d3-growth hormone receptor polymorphism is negatively associated with fetal growth but positively associated with postnatal growth in healthy subjects
    • Jensen RB, Vielwerth S, Larsen T, Greisen G, Leffers H, Juul A 2007 The presence of the d3-growth hormone receptor polymorphism is negatively associated with fetal growth but positively associated with postnatal growth in healthy subjects. J Clin Endocrinol Metab 92:2758-2763
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 2758-2763
    • Jensen, R.B.1    Vielwerth, S.2    Larsen, T.3    Greisen, G.4    Leffers, H.5    Juul, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.