Growth hormone (GH) dose, but not exon 3-deleted/full-length GH receptor polymorphism genotypes, influences growth response to two-year GH therapy in short small-for-gestational-age children

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 1, 2008, Pages 147-153

  Carrascosa, Antonio ^a,b   Audí, Laura ^a   Esteban, Cristina ^a   Fernández Cancio, Mónica ^a   Andaluz, Pilar ^a   Gussinyé, Miquel ^a   Clemente, María ^a   Yeste, Diego ^a   Albisu, María Angeles ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b HOSPITAL MATERNO INFANTIL VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RECEPTOR;

ARTICLE; BODY MASS; CHILD; CONTROLLED STUDY; EXON; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; GROWTH RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREPUBERTY; PRIORITY JOURNAL; SMALL FOR DATE INFANT; TREATMENT OUTCOME;

EID: 38149004249     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-1182     Document Type: Erratum

References (24)

1. Dos Santos C, Essioux L, Teinturier C, Tauber M, Goffin V, Bougneres P 2004 A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone. Nat Genet 36:720-724
2. Binder G, Baur F, Schweizer R, Ranke MB 2005 The d3-growth hormone receptor polymorphism is associated with increased responsiveness to GH in Turner Syndrome and in short small-for-gestational-age children. J Clin Endocrinol Metab 91:659-664
3. Carrascosa A, Esteban C, Espadero R, Fernandez-Cancio M, Andaluz P, Clemente M, Audi L, Wollmann H, Fryklund L, Parodi L, Spanish SGA Study Group 2006 The d3/fl-growth hormone (GH) receptor polymorphism does not influence the effect of GH treatment (66 μg/kg per day) or the spontaneous growth in short non-GH-deficient small-for-gestational-age children: results from a two-year controlled prospective study in 170 Spanish patients. J Clin Endocrinol Metab 91:3281-3286
4. Lee PA, Chernausek SD, Hokken-Koelega AC, Czernichow P, International Small for Gestational Age Advisory Board International 2003 International Small for Gestational Age Advisory Board consensus development conference statement: management of short children born small for gestational age, April 24-October 1, 2001. Pediatrics 111:1253-1261
5. Carrascosa A, Yeste D, Copil A, Gussinye M 2004 [Secular growth changes. Weight, height and body mass index values in infant, children, adolescent and young adults from Barcelona population]. Med Clin (Barc) 123:445-451 (Spanish)
6. Carrascosa A, Yeste D, Copil A, Almar J, Salcedo S, Gussinyé M 2004 [Anthropometric growth patterns of preterm and full-term newborns (24-42 weeks' gestational age) at the Hospital Materno-Infantil Vall d'Hebron (Barcelona)(1997-2002]. An Pediatr (Barc) 60:406-416 (Spanish)
7. Ferrández-Longas A, Baguer L, Labarta JI, Labena C, Mayayo E, Puga B, Rueda C, Ruiz-Echarri M 2005 Longitudinal study of normal Spanish children from birth to adulthood (anthropometric, pubertal, radiological and intellectual data). Pediatr Endocrinol Rev 2(Suppl 4):423-559
8. Elmlinger MW, Kühnel W, Weber MM, Ranke MB 2004 Reference ranges for two automated chemiluminescent assays for serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3). Clin Chem Lab Med 42:654-664
9. Pantel J, Machinis K, Sobrier ML, Duquesnoy P, Goossens M, Amselem S 2000 Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution. J Biol Chem 275:18664-18669
10. Audí L, Esteban C, Carrascosa A, Espadero R, Perez-Arroyo A, Arjona R, Clemente M, Wollmann H, Fryklund L, Parodi LA, Spanish SGA Study Group 2006 Exon 3-deleted/full-length growth hormone receptor polymorphism genotype frequencies in Spanish short small-for-gestational-age (SGA) children and adolescents (n = 247) and in an adult control population (n = 289) show increased fl/fl in short SGA. J Clin Endocrinol Metab 91:5038-5043
11. Coutant R, Carel JC, Letrait M, Chatelain P, Coste J, Chaussain JL 1998 Short stature associated with intrauterine growth retardation: final height of untreated and growth hormone-treated children. J Clin Endocrinol Metab 83:1070-1074
12. Carel JC, Chatelain P, Rochiccioli P, Chaussain JL 2003 Improvement in adult height after growth hormone treatment in adolescents with short stature born small for gestational age: results of a randomized controlled study. J Clin Endocrinol Metab 88:1587-1593
13. van Pareren Y, Mulder P, Houdijk M, Jansen M, Reeser M, Hokken-Koelega A 2003 Adult height after long-term continuous growth hormone (GH) treatment in short children born small for gestational age: results of a randomized, double-blind, dose-response GH trial. J Clin Endocrinol Metab 88:3584-3590
14. Dahlgren J, Wikland KA, Swedish Study Group for Growth Hormone Treatment 2005 Final height in short children born small for gestational age treated with growth hormone. Pediatr Res 57:216-222
15. Goddard AD, Covello R, Luoh SM, Clackson T, Attie KM, Gesundheit N, Rundle AC, Wells JA, Carlsson LM 1995 Mutations of the growth hormone receptor in children with idiopathic short stature. N Engl J Med 333:1093-1098
16. Sanchez J, Perera E, Baumbach L, Cleveland W 1998 Growth hormone receptor gene mutations in children with idiopathic short stature. J Clin Endocrinol Metab 83:4079-4083
17. Sjoberg M, Salazar T, Espinosa C, Dagnino A, Avila A, Eggers M, Cassorla F, Carvallo P, Mericq MV 2001 Study of GH sensitivity in Chilean patients with idiopathic short stature. J Clin Endocrinol Metab 86:4375-4381
18. Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfaffle R, Raile K, Seidel B, Smith RJ, Chernausek SD; Intrauterine Growth Retardation (IUGR) Study Group 2003 IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. N Engl J Med 349:2211-2222
19. Rosenfeld RG, Hwa V 2004 New molecular mechanisms of GH resistance. Eur J Endocirnol 151(Suppl 1):S11-S15
20. de Zegher F, Hokken-Koelega A 2005 Growth hormone therapy for children born small for gestational age: Height gain is less dose dependent over the long term than over the short term. Pediatrics 115:458-462
21. Jorge AA, Marchisotti FG, Montenegro LR, Carvalho LR, Mendonca BB, Arnhold IJ 2006 Growth hormone (GH) pharmacogenetics: influence of GH receptor exon 3 retention or deletion on first-year growth hormone response and final height in patients with severe GH deficiency. J Clin Endocrinol Metab 91:1076-1080
22. Pilotta A, Mella P, Filisetti M, Felappi B, Prandi E, Parrinello G, Notarangelo LD, Buzi F 2006 Common polymorphisms of the growth hormone (GH) receptor do not correlate with the growth response to exogenous recombinant human GH in GH-deficient children. J Clin Endocrinol Metab 91:1178-1180
23. Blum WF, Macchinis K, Shavrikova EP, Keller A, Stoble H, Phaeffle RW, Amselem S 2006 The growth response to growth hormone (GH) treatment in children with isolated GH deficiency is independent of the presence of the exon 3 minus isoform of the GH receptor. J Clin Endocrinol Metab 91:4171-4174
24. Horan M, Newsway V, Lewis YMD, Easter TE, Rees DA, Mahto A, Millar DS, Procter AM, Scanlon MF, Wilkinson IB, Hall IP, Wheatley A, Blakey J, Bath PMW, Cockcroft JR, Krawczak M, Cooper DN 2006 Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke. Hum Genet 119:527-540