Obesity decreases time to claudication and delays post-exercise hemodynamic recovery in elderly peripheral arterial disease patients

Gerontology

Volumn 55, Issue 1, 2009, Pages 21-26

  Ritti Dias, Raphael Mendes ^a,b   Forjaz, Cláudia Lúcia De Moraes ^a   Cucato, Gabriel Grizzo ^a   Costa, Luis Augusto Riani ^a   Câmara, Lucas Caseri ^a   Wolosker, Nelson ^a   Marucci, Maria De Fátima Nunes ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE   (Brazil)

Author keywords

Ankle brachial index; Exercise tolerance; Intermittent claudication; Pain

Indexed keywords

AGED; ANKLE BRACHIAL INDEX; ARTERY DISEASE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE DURATION; EXERCISE RECOVERY; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEMODYNAMICS; HUMAN; INTERMITTENT CLAUDICATION; MALE; MUSCLE METABOLISM; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RESPIRATORY FUNCTION; TREADMILL; WORKLOAD;

AGED; EXERCISE TEST; FEMALE; HEMODYNAMICS; HUMANS; INTERMITTENT CLAUDICATION; MALE; MIDDLE AGED; OBESITY; OXYGEN CONSUMPTION; PERIPHERAL VASCULAR DISEASES;

EID: 59749092615     PISSN: 0304324X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000155219     Document Type: Article

References (22)

1. Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, Rutherford RB: Inter-society consensus for the management of peripheral arterial disease. Int Angiol 2007;26:81-157.
2. Passos VM, Barreto SM, Guerra HL, Firmo JO, Vidigal PG, Lima-Costa MF: The Bambuí health and aging study (BHAS). Prevalence of intermittent claudication in the aged population of the community of Bambuíand its associated factors. Arq Bras Cardiol 2001;77:453-462.
3. Brevetti G, Schiano V, Chiariello M: Endothelial dysfunction: a key to the pathophysiology and natural history of peripheral arterial disease? Atherosclerosis 2008;197:1-11.
4. Sakamoto S, Ishikawa K, Senda S, Nakajima S, Matsuo H: The effect of obesity on ventilatory response and anaerobic threshold during exercise. J Med Syst 1993;17:227-231.
5. Shankar SS, Steinberg HO: Obesity and endothelial dysfunction. Semin Vasc Med 2005;5:56-64.
6. Hodnett BL, Hester RL: Regulation of muscle blood flow in obesity. Microcirculation 2007;14:273-288.
7. Planas A, ClaráA, Pou JM, Vidal-Barraquer F, Gasol A, de Moner A, Contreras C, Marrugat J: Relationship of obesity distribution and peripheral arterial occlusive disease in elderly men. Int J Obes Relat Metab Disord 2001;25:1068-1070.
8. Stewart KJ, Hiatt WR, Regensteiner JG, Hirsch AT: Exercise training for claudication. N Engl J Med 2002;347:1941-1951.
9. McDermott MM, Criqui MH, Ferrucci L, Guralnik JM, Tian L, Liu K, Greenland P, Tan J, Schneider JR, Clark E, Pearce WH: Obesity, weight change, and functional decline in peripheral arterial disease. J Vasc Surg 2006;43:1198-1204.
10. Fontaine R, Kim M, Kieny R: Surgical treatment of peripheral circulation disorders (in German). Helv Chir Acta 1954;21:499-533.
11. 2003 European Society of Hypertension - European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003;21:1011-1053.
12. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20:1183-1197.
13. Troiano RP, Frongillo EA Jr, Sobal J, Levitsky DA: The relationship between body weight and mortality: a quantitative analysis of combined information from existing studies. Int J Obes Relat Metab Disord 1996;20:63-75.
14. Gardner AW, Skinner JS, Cantwell BW, Smith LK: Progressive vs. single-stage treadmill tests for evaluation of claudication. Med Sci Sports Exerc 1991;23:402-408.
15. Hlavova A, Linhart J, Prerovsky I, Ganz V: Lactate and pyruvate changes in the leg during and after exercise in normal subjects and in patients with femoral artery occlusion. Clin Sci 1968;34:397-409.
16. Khimich S: Level of sensitivity of pain in patients with obesity. Acta Chir Hung 1997;36:166-167.
17. Signorelli SS, Mazzarino MC, Di Pino L, Malaponte G, Porto C, Pennisi G, Marchese G, Costa MP, Digrandi D, Celotta G, Virgilio V: High circulating levels of cytokines (IL-6 and TNF-α), adhesion molecules (VCAM-1 and ICAM-1) and selectins in patients with peripheral arterial disease at rest and after a treadmill test. Vasc Med 2003;8:15-19.
18. Lelkes PI, Hahn KL, Sukovich DA, Karmiol S, Schmidt DH: On the possible role of reactive oxygen species in angiogenesis. Adv Exp Med Biol 1998;454:295-310.
19. Green S, Askew CD, Walker PJ: Effect of type 2 diabetes mellitus on exercise intolerance and the physiological responses to exercise in peripheral arterial disease. Diabetologia 2007;50:859-866.
20. Zwierska I, Walker RD, Choksy SA, Male JS, Pockley AG, Saxton JM: Relative tolerance to upper- and lower-limb aerobic exercise in patients with peripheral arterial disease. Eur J Vasc Endovasc Surg 2006;31:157-163.
21. Opasich C, Pinna GD, Bobbio M, Sisti M, Demichelis B, Febo O, Forni G, Riccardi R, Riccardi PG, Capomolla S, Cobelli F, Tavazzi L: Peak exercise oxygen consumption in chronic heart failure: toward efficient use in the individual patient. J Am Coll Cardiol 1998;31:766-775.
22. Williams IL, Wheatcroft SB, Shah AM, Kearney MT: Obesity, atherosclerosis and the vascular endothelium: mechanisms of reduced nitric oxide bioavailability in obese humans. Int J Obes Relat Metab Disord 2002;26:754-764.